Results 41 to 50 of about 65,828 (262)
Biology Direct, 2021 Background Human bone marrow-derived mesenchymal stem cells (hBMSCs) are the primary source of osteoblasts in vivo. Emerging literatures have unveiled that circular RNAs (circRNAs) are actively drawn in the osteogenic differentiation of mesenchymal stem ...
Yuansheng Huang, Su Wan, Min Yang
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2021 Objective To investigate the association between the osteogenic differentiation in the soft tissue lump and the clinicopathological characteristics of osteosarcoma patients.
WU Zhaoyang +6 more
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Ghrelin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the ERK pathway. [PDF]
PLoS ONE, 2012 Vascular calcification results from osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and is a major risk factor for cardiovascular events. Ghrelin is a newly discovered bioactive peptide that acts as a natural endogenous ligand of the
Qiu-Hua Liang +12 more
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Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]
, 2017 Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu +4 more
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Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells
Cell Communication and Signaling, 2019 Background/aim Autophagy is a macromolecular degradation process playing a pivotal role in the maintenance of stem-like features and in the morpho-functional remodeling of the tissues undergoing differentiation.
Chiara Vidoni +7 more
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JAK2-STAT5B pathway and osteoblast differentiation [PDF]
JAK-STAT, 2013 Osteoblast differentiation is a critical step in the maintenance of bone homeostasis. Osteoblast differentiation is generally maintained by growth hormone (GH) and various other endocrine and autocrine/paracrine factors. JAK2-STAT5B pathway is a central axis in the mechanism of GH signaling.
Darvin, Pramod +2 more
openaire +2 more sources
The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]
, 2018 Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin +6 more
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Journal of Orthopaedic Surgery and Research, 2022 Background Emerging evidence has correlated the human antigen R (HuR) with the low-density lipoprotein receptor-related protein 6 (LRP6) gene, an important therapeutic target for osteoporosis.
Zelin Liu +4 more
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Bioactive sphene-based ceramic coatings on cpTi substrates for dental implants: An in vitro study [PDF]
, 2018 Titanium implant surface modifications have been widely investigated to favor the process of osseointegration. The present work aimed to evaluate the effect of sphene (CaTiSiO5) biocoating, on titanium substrates, on the in vitro osteogenic ...
Badocco, Denis +8 more
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Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition [PDF]
, 2019 Undernutrition in children is a pressing global health problem, manifested in part by impaired linear growth (stunting). Current nutritional interventions have been largely ineffective in overcoming stunting, emphasizing the need to obtain better ...
Ahern, Philip P. +13 more
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