Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen +5 more
wiley +1 more source
The iron-ferroptosis axis in bone homeostasis: a potential complementary pathway for osteoporosis in endometriosis. [PDF]
Motafeghi F +2 more
europepmc +1 more source
ABSTRACT Objectives This multicentre randomized controlled clinical trial aims to investigate the regenerative effects of various thicknesses and types of barrier materials with and without bone grafting in a rabbit calvaria model. Materials and Methods One hundred male rabbits were partitioned into two groups: one without bone graft (NB) and one with ...
Abdelsalam Elaskary +10 more
wiley +1 more source
Effects of Mechanical Stress on Bone and Cartilage Metabolism: How Mechanical Stress Affects Energy Metabolism in Bone and Cartilage Tissues (Our Research Overview): Mini Review. [PDF]
Iwata H +8 more
europepmc +1 more source
ABSTRACT Objectives This study aims to compare the efficacy of heterologous bone grafts to autologous dentine‐derived grafts (processed with the Tooth Transformer) in promoting bone regeneration in patients with posterior maxillary atrophy. Materials and Methods A prospective, split‐mouth study was performed on 15 patients (mean age 52 ± 8 years) with ...
Francesco Ferragina +3 more
wiley +1 more source
SLC25A mitochondrial carriers as biomarkers and therapeutic targets of spaceflight-induced dysfunction: the ADP/ATP carrier (AAC3) as a structural case study. [PDF]
D'Addabbo P +10 more
europepmc +1 more source
ABSTRACT Background Nutritional weight‐loss interventions are known to reduce bone mineral density (BMD), which can be prevented by adding (resistance) exercise training. However, this combined effect is not well studied in non‐obese adults. In addition, the association between biomarkers and metabolite‐based composite health markers with changes in ...
F. A. Bogaards +8 more
wiley +1 more source
Meta-Analysis of Ocy-454 Showed Interrupted Osteocyte Maturation in Spaceflight Affects SOST Expression and Hypoxic Response. [PDF]
Honjo M +3 more
europepmc +1 more source
Dental pulp stem cellderived exosomes and folic acid are evaluated for their effects on gene expression in an in‐vitro periodontal injury model. Human gingival fibroblasts subjected to oxidative and mechanical injury are treated with folic acid, exosomes, or their combination.
Saghar Zarei +4 more
wiley +1 more source
Effects of gold nanoparticles and apricot seeds on bone healing in New Zealand rabbits. [PDF]
Wally ZJ +6 more
europepmc +1 more source

