Results 31 to 40 of about 913,373 (166)

Radial Migration Dynamics Is Modulated in a Laminar and Area-Specific Manner During Primate Corticogenesis

Frontiers in Cell and Developmental Biology, 2020
The orderly radial migration of cortical neurons from their birthplace in the germinal zones to their final destination in the cortical plate is a prerequisite for the functional assembly of microcircuits in the neocortex.
Veronique Cortay, Delphine Delaunay, Dorothée Patti, Elodie Gautier, Nathalie Doerflinger, Pascale Giroud, Kenneth Knoblauch, Cyril Huissoud, Cyril Huissoud, Henry Kennedy, Henry Kennedy, Colette Dehay   +11 more
doaj   +1 more source

Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish

Neural Regeneration Research, 2023
The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development. However, its function in retina regeneration remains elusive.
Kaida Song, Zihao Lin, Lining Cao, Bowen Lu, Yuxi Chen, Shuqiang Zhang, Jianfeng Lu, Hui Xu   +7 more
doaj   +1 more source

Follow-up study of subventricular zone progenitors with multiple rounds of cell division during sulcogyrogenesis in the ferret cerebral cortex

IBRO Reports, 2019
The subventricular zone (SVZ) of the developing cerebral cortex appears transiently during cortical neurogenesis and is known as the second proliferative zone that contains intermediate progenitor cells and self-renewable neuronal stem cells—the so ...
Kazuhiko Sawada
doaj   +1 more source

Changes in the Localization of Polyamine Spermidine in the Rat Retina with Age

Biomedicines, 2023
Polyamines (PAs) in the nervous system has a key role in regeneration and aging. Therefore, we investigated age-related changes in the expression of PA spermidine (SPD) in the rat retina.
David S. Ríos, Christian J. Malpica-Nieves, Amanda Díaz-García, Misty J. Eaton, Serguei N. Skatchkov   +4 more
doaj   +1 more source

HOPX Defines Heterogeneity of Postnatal Subventricular Zone Neural Stem Cells

Stem Cell Reports, 2018
Summary: The largest diversity of neural lineages generated from the subventricular zone (SVZ) occurs early after birth and is regulated in a spatiotemporal manner depending on the expression of specific transcriptional cues.
Stefan Zweifel, Guillaume Marcy, Quentin Lo Guidice, Deqiang Li, Christophe Heinrich, Kasum Azim, Olivier Raineteau   +6 more
doaj   +1 more source

Outer brain barriers in rat and human development

Frontiers in Neuroscience, 2015
Complex barriers at the brain’s surface, particularly in development, are poorly defined. In the adult, arachnoid blood-cerebrospinal fluid (CSF) barrier separates the fenestrated dural vessels from the CSF by means of a cell layer joined by tight ...
Christian Beltoft Brøchner, Camilla Bjørnbak Holst, Kjeld eMøllgård   +2 more
doaj   +1 more source

What Makes Organoids Good Models of Human Neurogenesis?

Frontiers in Neuroscience, 2022
Human neurogenesis occurs mainly in embryonic, fetal, and neonatal stages and generates tremendously diverse neural cell types that constitute the human nervous system.
Qian Yang, Yan Hong, Ting Zhao, Hongjun Song, Hongjun Song, Hongjun Song, Hongjun Song, Guo-li Ming, Guo-li Ming, Guo-li Ming, Guo-li Ming   +10 more
doaj   +1 more source

Aluminum hydroxide exposure induces neurodevelopmental impairment in hESC-derived cerebral organoids

Ecotoxicology and Environmental Safety, 2023
Aluminum (Al) has been classified as a cumulative environmental pollutant that endangers human health. There is increasing evidence to suggest the toxic effects of Al, but the specific action on human brain development remains unclear.
Liuyongwei Wang, Linqiang Mei, Zhenle Zang, Yun Cai, Peiyan Jiang, Lianyu Zhou, Zhulin Du, Ling Yang, Zhanjun Gu, Tianyao Liu, Xiaotang Fan   +10 more
doaj   +1 more source

Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. [PDF]

, 2005
Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymmetric divisions.
Luciano Conti, Thorsten Gorba (59561), Mauro Toselli, Biella, G, Sanzone Sveva, Toselli, M, Austin Smith, Reitano Erika, Reitano, E, T. Gorba, Smith Austin, Steven M Pollard, E. Reitano, Sveva Sanzone (59566), BIELLA, GERARDO ROSARIO, Smith A., Reitano E, Gorba T, Ying Ql, Ying Qi-Long, Conti, L, Conti L, Sun Y, Sanzone, S, L. Conti, S. Sanzone, Toselli Mauro, Steven M Pollard (59560), Qi-Long Ying (59567), Q. L. Ying, Cattaneo Elena, Pollard, S M, Luciano Conti (59559), Y. R. Sun, Pollard Sm, Cattaneo E, Sun, Y R, Sveva Sanzone, Smith, A, Erika Reitano, Pollard Steven M, Yirui Sun, TOSELLI, MAURO GIUSEPPE, Thorsten Gorba, Ying, Q L, Yirui Sun (59565), Ying, QL, Conti Luciano, Gerardo Biella, Sun Yirui, Elena Cattaneo, E. Cattaneo, Mauro Toselli (59563), Austin Smith (59569), Qi-Long Ying, Biella Gerardo, Erika Reitano (59562), Pollard, SM, Cattaneo, E, Sanzone S, G. Biella, Gerardo Biella (59564), Gorba Thorsten, Gorba, T, A. Smith, Elena Cattaneo (59568), Sun, Y, S. M. Pollard, M. Toselli   +68 more
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Studying Human Outer Radial Glia Development in Pluripotent Stem Cells-derived Neural Cultures [PDF]

, 2022
The human neocortex is highly expanded and distinct from other species. Outer radial glia (oRG), a type of neural precursor (NPs), are thought to be responsible for the expansion of the human neocortex. Challenges remain in investigating oRG because they
Vu, Liona
core   +1 more source