Results 41 to 50 of about 913,373 (166)

Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development [PDF]

open access: yes, 2016
The classic view of cortical development, embodied in the radial unit hypothesis, highlights the ventricular radial glia (vRG) scaffold as a key architectonic feature of the developing neocortex.
Nowakowski, Tomasz J   +3 more
core   +1 more source

In vivo genetic manipulation of cortical progenitors in gyrencephalic carnivores using in utero electroporation

open access: yesBiology Open, 2012
Summary Brain structures such as the outer subventricular zone (OSVZ) and the inner fiber layer (IFL) in the developing cerebral cortex are especially prominent in higher mammals. However, the molecular mechanisms underlying the formation of the OSVZ are
Hiroshi Kawasaki   +2 more
doaj   +1 more source

Detailed morphology of tentacular apparatus and central nervous system in Owenia borealis (Annelida, Oweniidae)

open access: yesZoological Letters, 2021
The Oweniidae are marine annelids with many unusual features of organ system, development, morphology, and ultrastructure. Together with magelonids, oweniids have been placed within the Palaeoannelida, a sister group to all remaining annelids.
Elena Temereva   +2 more
doaj   +1 more source

Radial glia-like cell clones.

open access: yes, 2013
Radial glia-like cell clones.
Károly Markó (338625)   +5 more
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Real time imaging of human progenitor neurogenesis.

open access: yesPLoS ONE, 2010
Human neural progenitors are increasingly being employed in drug screens and emerging cell therapies targeted towards neurological disorders where neurogenesis is thought to play a key role including developmental disorders, Alzheimer's disease, and ...
Thomas M Keenan   +4 more
doaj   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Radial Glia in Echinoderms

open access: yes, 2019
Radial glial cells are crucial in vertebrate neural development and regeneration. It has been recently proposed that this neurogenic cell type might be older than the chordate lineage itself and might have been present in the last common deuterostome ...
Olga Zueva   +3 more
core   +1 more source

Radial glia phagocytose axonal debris from degenerating overextending axons in the developing olfactory bulb [PDF]

open access: yes, 2015
Axon targeting during the development of the olfactory system is not always accurate and numerous axons over-extend past the target layer into the deeper layers of the olfactory bulb.
Michael Wegner   +15 more
core   +1 more source

Cellular and Molecular Mechanisms regulating Cell Proliferation during the Forebrain Development of the Mouse [PDF]

open access: yes, 2005
The predominant precursor cell type during cortical neurogenesis are radial glia cells, which receive extrinsic and intrinsic signals that might influence cell proliferation and neurogenesis.
Haubst, Nicole, Haubst, N.
core   +1 more source

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