Results 101 to 110 of about 4,866 (174)

Antibiotics as selectors and accelerators 1 of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world [PDF]

, 2013
Antibiotics and antibiotic resistance determinants, natural molecules closely related to bacterial physiology and consistent with an ancient origin, are not only present in antibiotic-producing bacteria.
Cantón, Rafael, Galán, Juan Carlos, González Candelas, Fernando, Rolain, Jean-Marc   +3 more
core   +3 more sources

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Rapidly spreading Enterobacterales with OXA-48-like carbapenemases

Journal of Clinical Microbiology
Enterobacterales (mostly Klebsiella pneumoniae, Escherichia coli) with OXA-48-like carbapenemases (e.g., OXA-48, -181, -232, -244) are undermining the global efficiency of carbapenem therapy. In the Middle East, North Africa, and some European countries,
Gisele Peirano, Johann D. D. Pitout
doaj   +1 more source

In vitro evaluation of dual carbapenem combinations against carbapenemase-producing Enterobacteriaceae [PDF]

, 2016
Objectives: This study aimed to analyse the in vitro activity of dual combinations of carbapenems against Klebsiella pneumoniae producing the main carbapenemase types.Methods: MIC values of the carbapenems, imipenem, meropenem, ertapenem and doripenem ...
Kieffer, Nicolas, Nordmann, Patrice, Poirel, Laurent   +2 more
core  

The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023–2024

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys, fattening pigs and bovines under 1 year of age), and derived meat.
European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC)   +1 more
wiley   +1 more source

Dissemination of carbapenemase-producing Enterobacteriaceae in France, 2012 [PDF]

, 2016
Objectives Carbapenem-resistant Enterobacteriaceae isolates (n = 1485) were received at the French Associated National Reference Center for Antibiotic Resistance in 2012 and were characterized for their mechanism of resistance to carbapenems.
Cuzon, Gaelle, Dortet, Laurent, Nordmann, Patrice   +2 more
core  

Plasmid-mediated novel blaNDM-17 gene encoding a Carbapenemase with enhanced activity in a sequence type 48 Escherichia coli strain [PDF]

, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread worldwide, leaving very few treatment options available. New Delhi metallo-beta-lactamase (NDM) is the main carbapenemase mediating CRE resistance and is of increasing concern.
Li, Jiyun, Liu, Dejun, Liu, Zhihai, Shen, Jianzhong, Shen, Zhangqi, Walsh, Timothy Rutland, Wang, Yang, Yao, Hong, Yin, Wenjuan, Zhang, Rongmin   +9 more
core   +2 more sources

Clays for Low‐Carbon Cements: Overview, Progress, and Challenges

Global Challenges, Volume 10, Issue 1, January 2026.
This review provides a critical overview of recent developments of activated clays to function as artificial pozzolans. After a thorough description of the clays that yield good pozzolanic performances, selected examples are given on thermal and mechanical activations. Chiefly, general correlations are extracted from reported data despite its scattered
Imane Koufany, Isabel Santacruz, Angeles G. De la Torre, María D. Rodríguez‐Ruiz, Miguel A. G. Aranda   +4 more
wiley   +1 more source

NDM-1 and OXA-48-Like Carbapenemases (OXA-48, OXA-181 and OXA-252) Co-Producing Shewanella xiamenensis from Hospital Wastewater, China

Infection and Drug Resistance, 2022
Yicheng Wen,1,* Xiaofang Xie,1,* Ping Xu,2,* Chengcheng Yang,1 Zhichen Zhu,1 Jie Zhu,1 Jingnan Lv,1 Haifang Zhang,1 Liang Chen,3,4 Hong Du1 1Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou ...
Wen Y, Xie X, Xu P, Yang C, Zhu Z, Zhu J, Lv J, Zhang H, Chen L, Du H   +9 more
doaj  

The local paleoenvironment of Kalavan‐2 based on small‐vertebrate remains and its implications for human‐environment‐dynamics between 60 and 35 ka in the Armenian Highlands

Journal of Quaternary Science, Volume 41, Issue 1, Page 153-177, January 2026.
ABSTRACT Kalavan‐2, a high‐altitude (∼1640 m a.s.l.) open‐air site in Armenia, preserves stratified Middle Paleolithic occupations with a rich small‐vertebrate record. Luminescence dating has placed site formation between ~60 and 45 ka, but without independent chronological control of the microvertebrate accumulation.
Dominik L. Rogall, Monika V. Knul, Hugues‐Alexandre Blain, Boris Gasparyan, Ariel Malinsky‐Buller   +4 more
wiley   +1 more source