Results 101 to 110 of about 3,195 (172)

Molecular epidemiology of carbapenemase-producing Klebsiella pneumoniae in Gauteng South Africa

Scientific Reports
Klebsiella pneumoniae multidrug-resistant (MDR) high-risk clones drive the spread of antimicrobial resistance (AMR) associated infections, resulting in limited therapeutic options. This study described the genomic characteristics of K.
Kafilat T. Salvador-Oke, Johann D. D. Pitout, Gisele Peirano, Kathy-Anne Strydom, Chanel Kingsburgh, Marthie M. Ehlers, Arshad Ismail, Faustinos T. Takawira, Marleen M. Kock   +8 more
doaj   +1 more source

Antibiotic Resistance: A Genetic and Physiological Perspective

MedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy, Ahmed H. El‐Sappah, Rong Guo, Xiaoling Luo, Shiyuan Deng, Meifang Du, Xiaohong Jian, Mohammed Bakeer, Zaixin Li, Zhi Zhang   +9 more
wiley   +1 more source

Additional file 4 of Increased clonal dissemination of OXA-232-producing ST15 Klebsiella pneumoniae in Zhejiang, China from 2018 to 2021

, 2023
Additional file 4: Table S3. Antimicrobial susceptibility profiles of OXA-48-like-producing strains and transconjugants.
Zhang, Yanyan, Yang, Xuemei, Liu, Congcong, Huang, Ling, Shu, Lingbin, Sun, Qiaoling, Zhou, Hongwei, Huang, Yonglu, Cai, Chang, Wu, Xiaoyan, Chen, Sheng, Zhang, Rong   +11 more
openaire   +1 more source

Genomic and clinical characterisation of multidrug-resistant carbapenemase-producing ST231 and ST16 Klebsiella pneumoniae isolates colonising patients at Siriraj hospital, Bangkok, Thailand from 2015 to 2017

BMC Infectious Diseases, 2021
Background Infections caused by carbapenemase-producing Enterobacteriaceae (CPE) have continually grown as a global public health threat, with significant mortality rates observed across the world.
Adhiratha Boonyasiri, Elita Jauneikaite, Lauren M. Brinkac, Chris Greco, Kanokorn Lerdlamyong, Teerawit Tangkoskul, Kevin Nguyen, Visanu Thamlikitkul, Derrick E. Fouts   +8 more
doaj   +1 more source

Carbapenemase-producing organisms: a global scourge [PDF]

, 2018
The dramatic increase in the prevalence and clinical impact of infections caused by bacteria producing carbapenemases is a global health concern.
Bonomo, Robert A, Burd, Eileen M, Conly, John, Limbago, Brandi M, Poirel, Laurent, Segre, Julie A, Westblade, Lars F   +6 more
core  

Unveiling the Role of circRNAs in Pyroptotic Signalling: From Molecular Crosstalk to Disease Modulation

Journal of Cellular and Molecular Medicine, Volume 29, Issue 22, November 2025.
ABSTRACT Pyroptosis is a gasdermins‐dependent programmed cell death (PCD) characterised by progressive cellular swelling and plasma membrane rupture (PMR). This process releases intracellular contents that amplify inflammatory cascades and immune activation, involving the pathogenesis of various disorders such as tumours, heart and vascular diseases ...
Tengyu Jin, Guodong Xu, Wanru Zhou, Yige Shi, Hebo Wang   +4 more
wiley   +1 more source

Additional file 2 of Increased clonal dissemination of OXA-232-producing ST15 Klebsiella pneumoniae in Zhejiang, China from 2018 to 2021

, 2023
Additional file 2: Table S1. Sample Collection information in different regions of Zhejiang Province.
Zhang, Yanyan, Yang, Xuemei, Liu, Congcong, Huang, Ling, Shu, Lingbin, Sun, Qiaoling, Zhou, Hongwei, Huang, Yonglu, Cai, Chang, Wu, Xiaoyan, Chen, Sheng, Zhang, Rong   +11 more
openaire   +1 more source

Additional file 1 of Increased clonal dissemination of OXA-232-producing ST15 Klebsiella pneumoniae in Zhejiang, China from 2018 to 2021

, 2023
Additional file 1: Figure S1. Alignment of ColKP3-type plasmid.
Zhang, Yanyan, Yang, Xuemei, Liu, Congcong, Huang, Ling, Shu, Lingbin, Sun, Qiaoling, Zhou, Hongwei, Huang, Yonglu, Cai, Chang, Wu, Xiaoyan, Chen, Sheng, Zhang, Rong   +11 more
openaire   +1 more source

Advances in Enaminomaleimides Chemistry: Synthesis, Chemical Applications, and Perspectives

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
Enaminomaleimides are versatile building blocks for the construction of functionalized heterocycles. Their unique nucleophilic character, contrasting with the classical electrophilic nature of maleimides, enables diverse synthetic applications, showing promising potential in both materials science and medicinal chemistry.
Adrián López‐Francés, Birane Diop, Xingyu Jiang, Jean Rodriguez, Muriel Amatore, Thierry Constantieux   +5 more
wiley   +1 more source

Phenotypic and genotypic distribution of ESBL, AmpC β-lactamase and carbapenemase-producing Enterobacteriaceae in community-acquired and hospital-acquired urinary tract infections in Sri Lanka [PDF]

, 2022
Objectives: Although Sri Lanka belongs to a region with a high prevalence of extended-spectrum β-lactamase (ESBL), AmpC β-lactamase and carbapenemase-producing Enterobacteriaceae, data regarding antimicrobial resistance (AMR) is limited.
Aydin, A, Corea, EM, De Silva, HSM, de Silva, N, Enne, VI, Gamage, S, Jayatilleke, SK, Perera, PDVM   +7 more
core