Treatment Strategies for OXA-48-Like and NDM Producing Klebsiella pneumoniae Infections
Expert Review of Anti-Infective Therapy, 2022 Introduction OXA-48 and NDM are amongst the most prevalent carbapenemase types associated with Klebsiella pneumoniae worldwide, with an increase in their prevalence in recent years. Knowledge on the treatment of carbapenem-resistant Klebsiella pneumoniae
Murat Akova, Burcu Isler
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Genetic and Biochemical Characterization of OXA-519, a Novel OXA-48-Like β-Lactamase. [PDF]
Antimicrobial Agents and Chemotherapy, 2018 A multidrug-resistant 1210 isolate with reduced carbapenem susceptibility revealed the presence of a novel plasmid-encoded gene, named The 60.7-kb plasmid (pOXA-519) was similar to the IncL-OXA-48 prototypical plasmid except for a ca.
Laura Dabos +2 more
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OXA-48-Like Carbapenemases Producing Enterobacteriaceae in Different Niches
European Journal of Clinical Microbiology and Infectious Diseases, 2018 The emergence of carbapenem-resistant enterobacterialspecies poses a serious threat to public health worldwide.OXA-48-type carbapenem-hydrolyzing class D?- l a c tamas e s a r e widel y d i s t r i b u t e d amongEnterobacteriaceae, with significant ...
Assia Mairi, Alix Pantel
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Characterization of OXA-48-Like-Producing Enterobacteriaceae Isolated From River Water in Algeria
Water Research, 2017The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a significant problem for healthcare worldwide. The prevalence of carbapenem-resistant Enterobacteriaceae (CPE) in water environments in Algeria are unknown. The aim of this study was to screen for the presence of CPE isolates in the Soummam River in Bejaia, Algeria.
Jean-Marc Rolain +2 more
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Genetic and Biochemical Characterization of OXA-535, a Distantly Related OXA-48-Like β-Lactamase. [PDF]
Antimicrobial Agents and Chemotherapy, 2018 OXA-535 is a chromosome-encoded carbapenemase of Shewanella bicestrii JAB-1 that shares only 91.3% amino acid sequence identity with OXA-48. Catalytic efficiencies are similar to those of OXA-48 for most β-lactams, except for ertapenem, where a 2,000-fold-higher efficiency was observed with OXA-535.
Thierry Naas +2 more
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EMERGENCE OF OXA-48-LIKE CARBAPENEMASES IN CLINICAL ENTEROBACTERALES FROM GUATEMALA
ABSTRACT Five isolates (four Klebsiella pneumoniae and one Escherichia coli ) displaying resistance to piperacillin/tazobactam and ertapenem and reduced susceptibility to imipenem were found positive for bla OXA-Carmen J. Mazariegos +9 more
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OXA-48-like carbapenemase-producing Enterobacteriaceae in Ottawa, Canada
Diagnostic Microbiology and Infectious Disease, 2013Chelsey, Ellis +6 more
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Structural and functional insights into the substrate specificity of OXA-48-like carbapenemases
Etude structurale et fonctionnelle de la spécificité de substrat des carbapénèmases de type OXA-48 Les b-lactamines, grâce à leur efficacité clinique, sont parmi les antibiotiques les plus prescrits pour traiter des infections bactériennes.openaire +1 more source
Investigation Of Bla(Oxa-48)-Like Genes İn Carbapenemase Producing Klebsiella Spp. Isolates
2020The emergence and spread of multi-drug-resistant (MDR), extended-spectrum beta-lactamase (ESBL) producing carbapenem-resistant members of Enterobacteriaceae family has become a worldwide health problem. Carbapenem resistance caused by bla(KPC), bla(NDM) gene regions are sporadic and bla(OXA-48) gene region is endemic in our country.
Sakarya Üniversitesi/Tıp Fakültesi/Temel Tıp Bilimleri Bölümü +8 more
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