Antimicrobial resistance and phylogenetic lineages of KPC-2-producing blood-borne <i>Klebsiella pneumoniae</i> subsp. <i>pneumoniae</i> from Kolkata, India during 2015-2024: Emergence of <i>Klebsiella pneumoniae</i> subsp. <i>pneumoniae</i> with <i>bla</i><sub>KPC-2</sub>, <i>bla</i><sub>NDM</sub>, and <i>bla</i><sub>OXA-48-like</sub> triple carbapenemases. [PDF]
Halder G +15 more
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Francisca Sanchez-Jorquera +6 more
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OXA-48-like carbapenemases: the phantom menace [PDF]
OXA-48-type carbapenem-hydrolysing class D β-lactamases are increasingly reported in enterobacterial species. To date, six OXA-48-like variants have been identified, with OXA-48 being the most widespread. They differ by a few amino acid substitutions or deletions (one to five amino acids).
Laurent Poirel, Patrice Nordmann
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OXA-48-like carbapenemases producing Enterobacteriaceae in different niches [PDF]
The emergence of carbapenem-resistant enterobacterial species poses a serious threat to public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are widely distributed among Enterobacteriaceae, with significant geographical differences.
Assia Mairi, Alix Pantel, Albert Sotto
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Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK [PDF]
To characterize UK clinical isolates of Enterobacteriaceae producing OXA-48-like carbapenemases and to compare their resistance plasmids.Twenty-six enterobacteria producing OXA-48-like enzymes were studied. These were from 22 diverse hospitals in the UK.
David M Livermore, Neil Woodford
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Characterization of OXA-48-like-producing Enterobacteriaceae isolated from river water in Algeria
Water Research, 2017The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a significant problem for healthcare worldwide. The prevalence of carbapenem-resistant Enterobacteriaceae (CPE) in water environments in Algeria are unknown. The aim of this study was to screen for the presence of CPE isolates in the Soummam River in Bejaia, Algeria.
A Touati +2 more
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Treatment strategies for OXA-48-like and NDM producing Klebsiella pneumoniae infections
Expert Review of Anti-infective Therapy, 2022OXA-48 and NDM are amongst the most prevalent carbapenemase types associated with Klebsiella pneumoniae worldwide, with an increase in their prevalence in recent years. Knowledge on the treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) comes from KPC-producing CRKP with limited data available for OXA-48-like and NDM producers.
Burcu, Isler +4 more
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Ceftazidime-avibactam exhibits good in vitro activity against carbapenem resistant Klebsiella carrying OXA-48-like enzymes. We tested two hundred unique carbapenem resistant Klebsiella blood stream isolates (71% with single OXA-48-like carbapenemases, including OXA-48, n = 62; OXA-232, n = 57; OXA-244, n = 17; OXA-181, n = 5) that were collected as ...
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