Results 21 to 30 of about 30,682 (325)

The oxadiazole antibacterials [PDF]

Current Opinion in Microbiology, 2016
The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials exhibit activity against Gram-positive bacteria, including against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Shahriar Mobashery, Jeshina Janardhanan, Mayland Chang   +2 more
openaire   +3 more sources

Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi, Hiba Kadhum Yaseen   +1 more
doaj   +1 more source

Self Cycloaddition of o‐Naphthoquinone Nitrosomethide to (±) Spiro{naphthalene(naphthopyranofurazan)}‐one Oxide: An Insight into its Formation

ChemPlusChem, Volume 87, Issue 12, December 2022., 2022
2‐Hydroxy‐1‐naphthaldehyde oxime was oxidized by a D−A type self cycloaddition to spiro compound. Free reaction energy is calculated at −82.0 kcal/mol indicating its predominance over the intramolecular cyclization of −37.6 kcal/mol. 8‐methoxy substituted oxime is sterically guided to 9‐methoxynaphtho[1,2‐d] instead of spiro adduct resulting to the ...
Demeter Tzeli, Ioannis E. Gerontitis, Ioannis D. Petsalakis, Petros G. Tsoungas, George Varvounis   +4 more
wiley   +1 more source

SET activation of nitroarenes by 2-azaallyl anions as a straightforward access to 2,5-dihydro-1,2,4-oxadiazoles

Nature Communications, 2021
Oxadiazoles are five-membered ring heterocycles comprising an oxygen and two nitrogens, and those with the 1,2,4-oxadiazole skeleton are of interest due to their prevalence in biologically active compounds.
Dong Zou, Lishe Gan, Fan Yang, Huan Wang, Youge Pu, Jie Li, Patrick J. Walsh   +6 more
doaj   +1 more source

Evaluation of SSRT‐Test by Classical Gravimetric Analysis and Optical Topographic Measurement: A Comparative Study

Propellants, Explosives, Pyrotechnics, Volume 47, Issue 12, December 2022., 2022
Abstract To establish a database of performance values in the small‐scale shock reactivity test (SSRT), common secondary explosives based on organic nitrates (e. g. PETN) and nitramines (e. g. RDX and HMX) as well as aromatic (e. g. TNT), heteroaromatic (e. g. TKX‐50 and MAD−X1) and open chain systems (e. g. FOX‐7) were investigated.
Lukas Bauer, Maximilian Benz, Thomas M. Klapötke, Andreas Selmeier   +3 more
wiley   +1 more source

Cu(OH)x: Clay Catalyst Promoted Synthesis of 4,5-dihydro-1,2,4-oxadiazole at Room Temperature

Orbital: The Electronic Journal of Chemistry, 2017
An easy and efficient scheme is described designed for the preparation of 4,5-dihydro-1,2,4-oxadiazole using recyclable Cu(OH)x-Clay heterogeneous catalyst at room temperature.
Bashir Ahmad Dar, Zahed Zaheer, Samreen Fatema, Mazahar Farooqui   +3 more
doaj   +3 more sources

New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2

Molecules, 2021
A series of deoxycholic acid (DCA) amides containing benzyl ether groups on the steroid core were tested against the tyrosyl-DNA phosphodiesterase 1 (TDP1) and 2 (TDP2) enzymes.
Oksana V. Salomatina, Nadezhda S. Dyrkheeva, Irina I. Popadyuk, Alexandra L. Zakharenko, Ekaterina S. Ilina, Nina I. Komarova, Jóhannes Reynisson, Nariman F. Salakhutdinov, Olga I. Lavrik, Konstantin P. Volcho   +9 more
doaj   +1 more source

Photoredox Catalysis Enables Decarboxylative Cyclization with Hypervalent Iodine(III) Reagents: Access to 2,5-Disubstituted 1,3,4-Oxadiazoles.

Organic Letters, 2020
A novel approach to 2,5-disubstituted 1,3,4-oxadiazoles derivatives via a decarboxylative cyclization reaction by photoredox catalysis between commercially available α-oxocarboxylic acids and hypervalent iodine(III) reagent is described.
Jian Li, Xuechen Lu, Yue Xu, Jin-Xia Wen, Guoyu Hou, Li Liu   +5 more
semanticscholar   +1 more source

Microwave-Assisted Synthesis of Unsymmetrical 5-Phenyl-1,3,4-oxadiazoles Containing Bis(carboxymethyl)amino Group

Applied Sciences, 2023
New derivatives of 5-phenyl-1,3,4-oxadiazole substituted at position 2 with (bromomethyl)phenyl or bromoalkyl groups were obtained via microwave-assisted cyclodehydration of unsymmetrical N,N′-diacylhydrazines.
Marcin Łuczyński, Agnieszka Kudelko
doaj   +1 more source

Gas separation properties of new polyoxadiazole and polytriazole membranes [PDF]

, 1994
The gas separation properties of new aromatic poly-1,2,4-triazole and poly-1,3,4-oxadiazole membranes have been systematically investigated. Various functional groups were incorporated as pendent groups onto the polymer backbone of poly-1,2,4-triazoles ...
Borges-Sena, M.E.R., Hensema, E.R., Hensema, E.R., Mulder, M.H.V., Smolders, C.A., Smolders, C.A.   +5 more
core   +2 more sources