Synthesis of Oxazoles Containing CF3-Substituted Alcohol Unit via Tandem Cycloisomerization/Hydroxyalkylation from N-Propargylamides with Trifluoropyruvates [PDF]
MoleculesOxazoles are important five-membered heterocycles that contain both nitrogen and oxygen atoms. Due to their wide range of biological activities, many oxazoles demonstrate potential for extensive application in various fields, including medicinal ...
Juan-Juan Gao +6 more
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Synthesis and Optical Properties of N-Arylnaphtho- and Anthra[2,3-d]oxazol-2-amines [PDF]
MoleculesOxazole, a versatile and significant heteroarene, serves as a bridge between synthetic organic chemistry and applications in the medicinal, pharmaceutical, and industrial fields.
Yuki Murata +4 more
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Inter- and intramolecular Diels-Alder/retro-Diels-Alder reactions of 4-silylated oxazoles [PDF]
ARKIVOC, 2002 4-Silylated oxazoles have been shown to undergo inter- and intramolecular Diels-Alder/retro-Diels-Alder reactions with electron-poor alkynes to generate polysubstituted furans.
Pascal C. Ducept, Stephen P. Marsden
doaj +3 more sources
Synthetic Strategies to Access Fluorinated Azoles. [PDF]
European J Org ChemThis review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
El-Gaber MKA +4 more
europepmc +2 more sources
Core spectroscopy of oxazole [PDF]
The Journal of Chemical Physics, 2022 We have measured, analyzed, and simulated the ground state valence photoelectron spectrum, x-ray absorption (XA) spectrum, x-ray photoelectron (XP) spectrum as well as normal and resonant Auger–Meitner electron (AE) spectrum of oxazole at the carbon, oxygen, and nitrogen K-edge in order to understand its electronic structure.
Anna Kristina Schnack-Petersen +8 more
openaire +4 more sources
Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate [PDF]
Beilstein Journal of Organic Chemistry, 2020 The reactivity of α-azidochalcones has been explored for the preparation of highly substituted oxazoles via a 2H-azirine intermediate. The azidochalcones, when treated with potassium thiocyanate in the presence of potassium persulfate, lead to 2,4,5 ...
Mysore Bhyrappa Harisha +4 more
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Photochemical approach to functionalized benzobicyclo[3.2.1]octene structures via fused oxazoline derivatives from 4- and 5-(o-vinylstyryl)oxazoles [PDF]
Beilstein Journal of Organic Chemistry, 2014 Novel cis/trans-4- and cis/trans-5-(2-vinylstyryl)oxazoles have been synthesized by Wittig reactions from the diphosphonium salt of α,α’-o-xylene dibromide, formaldehyde and 4- and 5-oxazolecarbaldehydes, respectively. In contrast, trans-5-(2-vinylstyryl)
Ivana Šagud +3 more
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Benzo[d]oxazoles from Anilides by N-Deprotonation–O-SNAr Cyclization [PDF]
MoleculesA synthesis of benzo[d]oxazoles by an N-deprotonation–O-SNAr cyclization sequence from anilide precursors is reported. Anilides derived from 2-fluorobenzaldehydes, activated toward SNAr ring closure by C5 electron-withdrawing groups, were prepared and ...
Nash E. Nevels +2 more
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Polarizability in Substituted Oxazoles: A PC-Model Data Analysis [PDF]
E-Journal of Chemistry, 2005 A systematic investigation of various Oxazole derivatives has been subjected to a Polarized Continuums Model (PCM) for evaluation of their physico-chemical parameters.
S. Harikrishna +3 more
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Oxazole and thiazole analogs of sulindac for cancer prevention [PDF]
, 2018 Aim: Experimental and epidemiological studies and clinical trials suggest that nonsteroidal anti-inflammatory drugs possess antitumor potential. Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and ...
Connelly, Michele C. +4 more
core +4 more sources