Results 91 to 100 of about 14,648 (255)
Smart Molecules, EarlyView.In this work, we developed a complex‐mediated nucleophilic aromatic substitution which can generate rich D‐A AIEgens under a facile condition. The AIE mechanism of such AIEgens was unveiled and their application towards fatty liver imaging was exhibited. Abstract Donor‐acceptor (D‐A) compounds are particularly important in optoelectronic and biological
Feng Liu +12 more
wiley +1 more source
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Molecules, 2013 Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj +1 more source
Cell Proliferation, EarlyView.KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee +13 more
wiley +1 more source
Synthesis and antitumor activity of mechercharmycin A analogues [PDF]
, 2014 Several analogs of the cytotoxic thiopeptide IB-01211 or Mechercharmycin A (1) have been synthetized. The cytotoxicity of 1 and the synthetized analogs was evaluated against a panel of three human tumor cell lines.
Albericio Palomera, Fernando +5 more
core +2 more sources
Reaction Kinetics of NH2 With H2CO and CH3CHO: Modeling Implications for NH3‐Dual Fuel Blends
International Journal of Chemical Kinetics, Volume 57, Issue 7, Page 403-416, July 2025.ABSTRACT Carbon‐free fuels like ammonia (NH3) and hydrogen (H₂) offer significant potential in combating global warming by reducing greenhouse gas emissions and moving toward zero carbon emissions. Over the past few years, our research has focused on understanding the combustion behavior of carbon‐neutral and carbon‐free fuels.
Krishna Prasad Shrestha +8 more
wiley +1 more source
Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin [PDF]
, 2017 The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a linear array of amino acids that also contains two dehydroalanine residues.
Arnison +22 more
core +2 more sources
New heterocycles having double characters; as antimicrobial and surface active agents.
Grasas y Aceites, 2004 Fatty acids isothiocyanate (1) was used as a starting material to synthesize some important heterocycles such as triazoles, oxazoles, thiazoles, benzoxazoles and quinazolines by treating with different types of nucleophiles such as nitrogen nucleophiles,
M. S. Amine +4 more
doaj +1 more source
Non linear Prediction of Antitubercular Activity Of Oxazolines and Oxazoles derivatives Making Use of Compact TS-Fuzzy models Through Clustering with orthogonal least sqaure technique and Fuzzy identification system [PDF]
arXiv, 2014 The prediction of uncertain and predictive nonlinear systems is an important and challenging problem. Fuzzy logic models are often a good choice to describe such systems however in many cases these become complex soon. commonlly, too less effort is put into descriptor selection and in the creation of suitable local rules.
arxiv
Sorption of Sulfonamide Antibiotics in Peat Soils With Different Properties
Journal of Plant Nutrition and Soil Science, Volume 188, Issue 3, Page 482-494, June 2025.Sulfonamide antibiotics contaminate peat soils where they are sorbed to functional groups in a pH‐dependent manner that can be successfully described by QSAR. ABSTRACT Background Sulfonamide antibiotics have been discovered as emerging pharmaceutical pollutants worldwide and are only poorly removed in wastewater treatment.
Eric Mirenga, Sören Thiele‐Bruhn
wiley +1 more source
Synthesis, Structural Elucidation and Bioassay of Morpholine/Thiomorpholine and Piperidine Containing Oxazoles [PDF]
, 2019 The series of novel oxazole derivatives (3-4) have been synthesized. All the entitles compounds were characterized by IR, 1H, 13C NMR, mass spectra. All the lead compounds were tested for antimicrobial activity.
Bakthavatchala Reddy, N. +3 more
core +2 more sources