The Role of N6‐Methyladenosine Modification in Health and Disease
MedComm, Volume 7, Issue 6, June 2026.N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
Leveraging the Oxford Nanopore MinION sequencing platform for HIV-1 drug resistance surveillance in resource-limited settings: a post-COVID implementation opportunity. [PDF]
Virol JWashaya T +6 more
europepmc +1 more source
New Zealand Journal of Botany, Volume 64, Issue 2, June 2026.Molecular phylogenetic markers used to be ubiquitously obtained by Sanger sequencing, while recently, next generation sequencing (NGS) approaches have become popular alternatives. In this study, a pipeline utilizing Oxford Nanopore Technologies (ONT) amplicon sequencing (amplicon‐seq) was examined as an alternative to Sanger sequencing, with nine loci [
Kanae Nishii +7 more
wiley +1 more source
Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing
The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz +5 more
wiley +1 more source
Methylome Profiling of a Deuterostome Invertebrate Using Oxford Nanopore Technology (ONT). [PDF]
Mol Ecol ResourKwong SLT +4 more
europepmc +1 more source
The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Bean rust, caused by Uromyces appendiculatus, severely limits the productivity of common bean (Phaseolus vulgaris L.), an essential source of protein and micronutrients in human diets worldwide. Durable disease management relies primarily on host resistance; however, the molecular architecture of several key rust resistance loci remains ...
Alvaro Soler‐Garzón +4 more
wiley +1 more source
De novo whole genome assembly of the globally invasive green shore crab Carcinus maenas (Linnaeus, 1758) via long-read Oxford Nanopore MinION sequencing. [PDF]
J HeredBrons JK +5 more
europepmc +1 more source
Kineochelins—A New Group of Siderophores From an Antarctic Bacterium
Microbial Biotechnology, Volume 19, Issue 6, June 2026.Genome‐guided analysis of an Antarctic Actinokineospora strain led to the discovery of kineochelins, a new group of siderophores involved in iron sequestration and microbial competition. Kineochelin production inhibits co‐occurring bacteria and clinically relevant yeasts, highlighting Antarctic microorganisms as promising sources of bioactive natural ...
Stanislava Kralova +12 more
wiley +1 more source
Novel features of <i>Mycoplasma genitalium</i> genomes identified through Oxford Nanopore sequence analysis of isolates from Australia. [PDF]
Microb GenomHuaman JL +7 more
europepmc +1 more source
Microbial Biotechnology, Volume 19, Issue 6, June 2026.Phages that infect the oak pathogens Brenneria goodwinii and Gibbsiella quercinecans were isolated. The phages were able to effectively reduce bacterial populations of their respective hosts in vitro. However, when applied in planta, the phages did not reduce host populations and instead phages and bacteria co‐existed over time.
Emily R. Grace +7 more
wiley +1 more source