ABSTRACT Valid pre‐clinical animal models are essential for effective drug development in inflammatory skin diseases like atopic dermatitis. Most murine models exhibit low‐to‐moderate inflammatory responses with significant variability, undermining their validity and contributing to high drug attrition rates.
Ida Wang Henriksen +5 more
wiley +1 more source
Comparative analysis of illumina and oxford nanopore sequencing platforms for 16S rRNA profiling of respiratory microbial communities. [PDF]
Macip G +12 more
europepmc +1 more source
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro +4 more
wiley +1 more source
TAILcaller: an R package for analyzing differences in poly(A) tail length for Oxford Nanopore RNA sequencing. [PDF]
Maździarz M, Paukszto Ł, Sawicki J.
europepmc +1 more source
Summary The evolutionary origin of red algae‐derived complex plastids remains obscure. Cryptophyta, one of four eukaryotic lineages harboring these plastids, still contains nucleomorphs, which are highly reduced remnants of red algal nuclei. The genes present on nucleomorph genomes can be used for phylogenomic reconstruction in order to unravel the ...
Lukáš V. F. Novák +6 more
wiley +1 more source
Reliable investigation of DNA methylation using Oxford nanopore technologies. [PDF]
Doshi R +4 more
europepmc +1 more source
Benchmarking Illumina and Oxford Nanopore Technologies (ONT) sequencing platforms for whole genome sequencing of bacterial genomes and use in clinical microbiology. [PDF]
Purushothaman S +3 more
europepmc +1 more source
Comparative evaluation of Oxford Nanopore Technologies' adaptive sampling and the Twist long-read PGx panel for pharmacogenomic profiling. [PDF]
Deserranno K +3 more
europepmc +1 more source
NanoMLST: A High-Throughput Bacterial Multi-Locus Sequence Typing Workflow Using Oxford Nanopore Next-Generation Sequencing for ESKAPE + E Pathogens. [PDF]
García-Pérez I +10 more
europepmc +1 more source

