Results 131 to 140 of about 25,431 (290)

De novo Nanopore read quality improvement using deep learning

BMC Bioinformatics, 2019
Background Long read sequencing technologies such as Oxford Nanopore can greatly decrease the complexity of de novo genome assembly and large structural variation identification.
Nathan LaPierre, Rob Egan, Wei Wang, Zhong Wang   +3 more
doaj   +1 more source

High-Coverage Long Read DNA Sequencing with the Oxford Nanopore MinION [PDF]

, 2017
Nanopore sequencing was conceived in 1989 by Dave Deamer (UCSC). Over two decades of development from research laboratories and, later on, Oxford Nanopore Technologies resulted in the MinION nanopore sequencer.
Jain, Miten
core  

Biosurfactant production by Pseudomonas aeruginosa isolated from mining waste: From genomic analysis to development of a polymeric composite for removal of hexavalent chromium

Polymer International, EarlyView.
Biosurfactant was produced by Pseudomonas aeruginosa using andiroba waste from Amazonia. A biosurfactant–alginate composite (Alg/BioS) was successfully synthesized via ionotropic gelation, and achieved up to 70% Cr6+ removal from water. Abstract Environmental contamination by heavy metals represents a significant challenge due to their persistence in ...
Paulo Diniz Austriaco, Emilly Cruz da Silva, Glenda Sores Gomes, Joane Almeida Alves, Amanda Vidal, Leandro Argolo, Rafaela Ribeiro, Luciana Souza, José Augusto Pires Bitencourt, Leonardo Brasil Felipe, Leonie Asfora Sarubbo, Sidnei Cerqueira dos Santos   +11 more
wiley   +1 more source

Methodological development of human telomere sequencing with the Oxford Nanopore Technologies

, 2023
Human DNA is protected with telomeres, which consist of the repetitive DNA-sequence TTAGGG. A 3’-overhang folds back and in combination with the shelterin complex protects the ends of the DNA. Telomeres shorten over time due to the end replication problem in cell proliferation which eventually leads to senescence or apoptosis, making the telomeres an ...
openaire   +1 more source

Transcriptomic stress responses in Vaccinium spp. F1 hybrids: Implications for temperature‐resilient cranberry breeding using a crop wild relative

PLANTS, PEOPLE, PLANET, EarlyView.
Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson, Jackson Kubal, Nicholas Allsing, Emily Murray, Todd P. Michael, James J. Polashock   +5 more
wiley   +1 more source

Oxford Nanopore Technologies: long-read sequencing for the enhancement of diagnostic analysis of rare monogenic diseases

openLa diagnosi di malattie monogeniche rare ad oggi rimane spesso incompleta a causa delle limitazioni delle tecniche di sequenziamento short-read. Pertanto, una soluzione possibile è l’utilizzo in ambito diagnostico di tecniche di sequenziamento long-
DALL'ARMI, ELENA
core  

Applications of Nanopore sequencing in precision cancer medicine

Oxford Nanopore Technologies sequencing, also referred to as Nanopore sequencing, stands at the forefront of a revolution in clinical genetics, offering the potential for rapid, long read, and real‐time DNA and RNA sequencing.
Joosse, Simon A., von Amsberg, Gunhild, Afflerbach, Ann‐Kristin, Dyshlovoy, Sergey A., Lobermeyer, Annabelle, Paigin, Stefanie, Bokemeyer, Carsten, Bergmann, Lina, Werner, Stefan, Schüller, Ulrich, Schuh, Anna H.   +10 more
core   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Methods of processing Oxford Nanopore sequencing data for metagenomics

, 2018
The revolutionary sequencing technology introduced by Oxford Nanopore Technologies – MinION holds a great promise in the field of metagenomics. Low cost, produced long reads and portability, due to its small dimensions, represents only one of the many ...
Barilíková, Lujza
core   +1 more source

1D Genome Sequencing on the Oxford Nanopore MinION

, 2017
Today's short-read sequencing instruments can generate read lengths between 50 bp and 700 bp depending on the specific instrument. These high-throughput sequencing approaches have revolutionized genomic science, allowing hundreds of thousands of full ...
Goodwin, S., McCombie, W. R., Wappel, R.   +2 more
core   +1 more source