Results 61 to 70 of about 8,483 (210)

Chirality transfer in metal-­‐catalysed intermolecular addition reactions involving allenes [PDF]

open access: yes, 2016
Allene chemistry in the presence of transition metal complexes is nowadays a very important topic that underpins many challenges and advances in organic synthesis.
Abe   +169 more
core   +1 more source

Novel Application of UHPLC–MS, HRMS, and 2D‐NMR for Structural Elucidation of Eletriptan Hydrobromide and Its Novel Degradation Products

open access: yesBiomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT A stability‐indicating UHPLC–MS method was developed to investigate the stress degradation behavior of eletriptan hydrobromide under ICH‐recommended acidic, alkaline, neutral, oxidative, thermal, and photolytic conditions. Significant degradation was observed only under acidic and oxidative stress.
Dastagiri Reddy Bhuma   +3 more
wiley   +1 more source

Environmental Influence on the Untargeted Foliar Metabolome of Naturally Growing Mitragyna Species in Thailand

open access: yesPlant-Environment Interactions, Volume 7, Issue 1, February 2026.
ABSTRACT This study investigates the foliar secondary metabolite profiles of four Mitragyna species naturally occurring in Thailand: M. diversifolia, M. hirsuta, M. rotundifolia, and M. speciosa (kratom). Using untargeted gas chromatography–mass spectrometry (GC–MS), 409 secondary volatile metabolites were annotated across the four species.
Tushar Andriyas   +5 more
wiley   +1 more source

Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3′-oxindoles] under Microwave Irradiation and Their Anticancer Activity

open access: yesMolecules, 2023
A novel series of nitrostyrene-based spirooxindoles were synthesized via the reaction of substituted isatins 1a–b, a number of α-amino acids 2a–e and (E)-2-aryl-1-nitroethenes 3a–e in a chemo/regio-selective manner using [3+2] cycloaddition (Huisgen ...
Richa Sharma   +12 more
doaj   +1 more source

A novel mechanism of auxin habituation: upregulation of auxin receptor TRANSPORT INHIBITOR RESPONSE 1 allows cell proliferation independent of external auxin

open access: yesNew Phytologist, Volume 249, Issue 3, Page 1268-1282, February 2026.
Summary Exogenously applied auxins are essential for establishing cell lines in tissue cultures and maintaining their proliferation. Cell lines may develop the ability to proliferate even in media lacking auxin, they may become auxin‐habituated. This study investigated the mechanisms underlying this process.
Pavel Jelínek   +11 more
wiley   +1 more source

SYNTHESIS AND ANTIVIRAL ACTIVITY OF NEW THIAZOLE, 1,2,4-TRIAZOL AND OXINDOLE DERIVATIVES [PDF]

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2011
The synthesis and antiviral activity evaluation of new derivatives of 2-aminothiazole, 1,2,4-triazole, as well as oxindoles has been realized. The synthesized compounds exhibited different cytotoxicity, in particular, oxindols 4 , 5 , 7 , 8 , 9, 10, 11,
Oleg Radul   +5 more
doaj  

A novel methodology for the efficient synthesis of 3-monohalooxindoles by acidolysis of 3-phosphate-substituted oxindoles with haloid acids

open access: yesBeilstein Journal of Organic Chemistry, 2021
A novel method for the synthesis of 3-monohalooxindoles by acidolysis of isatin-derived 3-phosphate-substituted oxindoles with haloid acids was developed.
Li Liu   +4 more
doaj   +1 more source

Development of Bifunctional Chiral Thioureas and Thiosquaramides in the Synthesis of Betti Bases

open access: yesMolecules, 2023
Bifunctional thioureas and, for the first time, bifunctional thiosquaramides as organocatalysts were used in the asymmetric Betti reaction involving 1-, 2-naphthols and hydroxyquinoline with N-tosylimine and ketimine.
Martyna Malinowska, Anna Zawisza
doaj   +1 more source

Recent advances in homogeneous borrowing hydrogen catalysis using earth-abundant first row transition metals [PDF]

open access: yes, 2019
The review highlights the recent advances (2013-present) in the use of earth-abundant first row transition metals in homogeneous borrowing hydrogen catalysis. The utility of catalysts based on Mn, Fe, Co, Ni and Cu to promote a diverse array of important
Morrill, Louis C.   +2 more
core   +2 more sources

Methyl isocyanide as a convertible functional group for the synthesis of spirocyclic oxindole γ-lactams via post-Ugi-4CR/transamidation/cyclization in a one-pot, three-step sequence

open access: yesBeilstein Journal of Organic Chemistry, 2018
The synthesis of spiro[indoline-3,2'-pyrrole]-2,5'(1'H)-diones and spiro[indoline-3,2'-pyrrolidine]-2,5'-diones, via a post-Ugi-domino transamidation/cyclization sequential process, has been achieved in three sequential steps utilizing a one-pot reaction
Amarendar Reddy Maddirala   +1 more
doaj   +1 more source

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