Results 41 to 50 of about 12,832 (200)

Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size [PDF]

, 2016
Calcium-independent phospholipase A(2)γ (iPLA(2)γ) is a mitochondrial enzyme that produces lipid second messengers that facilitate opening of the mitochondrial permeability transition pore (mPTP) and contribute to the production of oxidized fatty acids ...
Abendschein, Dana, Gibson Dilthey, Beverly, Gross, Richard W, Guan, Shaoping, Jenkins, Christopher M, Kovacs, Attila, Liu, Xinping, Mancuso, David J, Moon, Sung Ho, Nguyen, Annie L, Sims, Harold F, Weinheimer, Carla J, Yang, Kui   +12 more
core   +2 more sources

A single meal has the potential to alter brain oxylipin content. [PDF]

, 2020
Our objective was to determine whether consumption of a single meal has the potential to alter brain oxylipin content. We examined the cerebrum of mice fed a single high-fat/high-sucrose Western meal or a low-fat/low-sucrose control meal, as well as ...
Aung, HH, Norman, JE, Otoki, Y, Rutledge, JC, Taha, AY, Zhang, Z   +5 more
core   +1 more source

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Potential of Plasma Oxylipin Signature to Better Understand the Relationships between Diet, Fatty Acids and Oxylipins in Healthy Individuals: New Insights from Two Independent Cohort Studies

Proceedings
Eicosanoids and other oxylipins represent a superfamily of bioactive lipids involved in the regulation of crucial biological processes such as inflammation, blood clotting or endothelial reactivity.
Cécile Gladine, Nils Schebb, Mathilde Touvier, Arne Astrup, Philip Calder, Andrzej Szuba, John Newman   +6 more
doaj   +1 more source

Obesity-induced changes in lipid mediators persist after weight loss. [PDF]

, 2017
BackgroundObesity induces significant changes in lipid mediators, however, the extent to which these changes persist after weight loss has not been investigated.Subjects/methodsWe fed C57BL6 mice a high-fat diet to generate obesity and then switched the ...
Börgeson, E, Hernandez-Carretero, A, La Frano, MR, Lantero Rodriguez, J, Newman, JW, Osborn, O, Sears, DD, Wallenius, V, Weber, N, Ying, W   +9 more
core   +2 more sources

Lipids in Aspergillus flavus-maize interaction

Frontiers in Microbiology, 2014
In sSome filamentous fungi, the pathways related to the oxidative stress and oxylipins production are involved both in the process of host-recognition of the host that and in the pathogenic phase. In fact, recent studies have shown that the production of
Massimo eReverberi, marzia escarpari, emanuela ecamera, matteo eludovici, chiara enobili, marta epunelli, marco ezaccaria, valeria escala, corrado efanelli, anna adele fabbri   +9 more
doaj   +1 more source

Differential effects of EPA vs. DHA on postprandial vascular function and the plasma oxylipin profile in men [PDF]

, 2016
Our objective was to investigate the impact of EPA versus DHA, on arterial stiffness and reactivity, and underlying mechanisms (with a focus on plasma oxylipins), in the postprandial state.
Aedin Cassidy, Anne Marie Minihane, Armah, Asmar, Balakumar, Berry, Bonetti, Chong, Conquer, David Vauzour, Feelisch, Fischer, Flammer, Frömel, Hallund, Hickson, Huang, Ingrid Fleming, Jackson, Janner, Janner, Khader Awwad, Lauer, Lind, Lithander, Macready, Martin, Michaelis, Miller, Mitchell, Moerland, Mori, Morin, Morin, Mozaffarian, Mozaffarian, Mustafa, Neil Rigby, Noemi Tejera, Nürnberger, Pase, Psychogios, Pucci, Purcell, Ras, Rontoyanni, Ruiz-Lopez, Salem, Saravanan, Schebb, Schächinger, Seán McManus, Shearer, Shearer, Shen, Siasos, Strassburg, Vauzour, Vlachopoulos, Wang, Wang, West, Wilson, Ye   +63 more
core   +1 more source

Bioactive C₁₇ and C₁₈ Acetylenic Oxylipins from Terrestrial Plants as Potential Lead Compounds for Anticancer Drug Development

Molecules, 2020
Bioactive C17 and C18 acetylenic oxylipins have shown to contribute to the cytotoxic, anti-inflammatory, and potential anticancer properties of terrestrial plants.
Lars Porskjær Christensen
doaj   +1 more source

Oxylipin profile in saliva from patients with cystic fibrosis reveals a balance between pro-resolving and pro-inflammatory molecules

Scientific Reports, 2022
Oxylipins are signaling molecules originated by fatty acids that modulate vascular and bronchial tone, bronchial secretion, cytokine production and immune cell activity.
Vincenzo Carnovale, Alice Castaldo, Alessandro Di Minno, Monica Gelzo, Paola Iacotucci, Anna Illiano, Gabriella Pinto, Giuseppe Castaldo, Angela Amoresano   +8 more
doaj   +1 more source

Fungal and bacterial oxylipins are signals for intra- and inter-cellular communication within plant disease

Frontiers in Plant Science, 2022
Lipids are central at various stages of host–pathogen interactions in determining virulence and modulating plant defense. Free fatty acids may act as substrates for oxidizing enzymes [e.g., lipoxygenases (LOXs) and dioxygenases (DOXs)] that synthesize ...
Marzia Beccaccioli, Nicoletta Pucci, Manuel Salustri, Marco Scortichini, Marco Zaccaria, Babak Momeni, Stefania Loreti, Massimo Reverberi, Valeria Scala   +8 more
doaj   +1 more source