Results 51 to 60 of about 12,832 (200)

Multifunctional Enzymes in Oxylipin Metabolism

ChemBioChem, 2008
Fingers in lots of pies: For the first time a member of the CYP74 enzyme subfamily (9‐AOS) from tomato has been shown by chemical and analytical approaches to catalyze multiple reactions. These multifunctional properties of 9‐AOS from the oxylipin‐forming lipoxygenase (LOX) pathway raise several new questions on lipid‐derived signaling.
Wasternack, Claus, Feussner, Ivo
openaire   +3 more sources

Effects of hemodialysis on plasma oxylipins [PDF]

Physiological Reports, 2020
Chronic kidney disease (CKD) is an important risk factor for cardiovascular and all-cause mortality. Survival rates among end-stage renal disease (ESRD) hemodialysis patients are poor and most deaths are related to cardiovascular disease. Oxylipins constitute a family of oxygenated natural products, formed from fatty acid by pathways involving at least
Benjamin Gollasch, Guanlin Wu, Inci Dogan, Michael Rothe, Maik Gollasch, Friedrich C. Luft   +5 more
openaire   +4 more sources

Modern Methods of Sample Preparation for the Analysis of Oxylipins in Biological Samples

Molecules, 2019
Oxylipins are potent lipid mediators derived from polyunsaturated fatty acids, which play important roles in various biological processes. Being important regulators and/or markers of a wide range of normal and pathological processes, oxylipins are ...
Ivan Liakh, Alicja Pakiet, Tomasz Sledzinski, Adriana Mika   +3 more
doaj   +1 more source

Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

Frontiers in Immunology, 2023
IntroductionPremature infants (PIs) are at risk of suffering necrotizing enterocolitis (NEC), and infants consuming human milk (HM) show a lower incidence than infants receiving formula.
Marta Gómez-Ferrer, Elena Amaro-Prellezo, Abel Albiach-Delgado, Isabel Ten-Domenech, Julia Kuligowski, Pilar Sepúlveda, Pilar Sepúlveda, Pilar Sepúlveda, Pilar Sepúlveda   +8 more
doaj   +1 more source

CYP450-derived oxylipins mediate inflammatory resolution [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance A number of lipid mediators are known to contribute to inflammatory resolution. Fatty acid metabolites of cytochrome P450 (CYP) enzymes are found in abundance; however, their roles in inflammatory resolution are not known.
Derek W. Gilroy, Matthew L. Edin, Roel P. H. De Maeyer, Jonas Bystrom, Justine Newson, Fred B. Lih, Melanie Stables, Darryl C. Zeldin, David Bishop-Bailey   +8 more
openaire   +4 more sources

Biologically Active Oxylipins from Enzymatic and Nonenzymatic Routes in Macroalgae

Marine Drugs, 2016
Marine algae are rich and heterogeneous sources of great chemical diversity, among which oxylipins are a well-recognized class of natural products. Algal oxylipins comprise an assortment of oxygenated, halogenated, and unsaturated functional groups and ...
Mariana Barbosa, Patrícia Valentão, Paula B. Andrade   +2 more
doaj   +1 more source

Serum levels of oxylipins in achilles tendinopathy: an exploratory study. [PDF]

PLoS ONE, 2015
BACKGROUND:Linoleic acid-derived oxidation products are found in experimental pain models. However, little is known about the levels of such oxylipins in human pain.
Sandra Gouveia-Figueira, Malin L Nording, Jamie E Gaida, Sture Forsgren, Håkan Alfredson, Christopher J Fowler   +5 more
doaj   +1 more source

TGA2 signaling in response to reactive electrophile species is not dependent on cysteine modification of TGA2 [PDF]

, 2018
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Reactive ...
A Mosblech, B Fode, C Boettcher, C Despres, C Lindermayr, C Loeffler, C Stange, C Thurow, C Wasternack, Christiane Gatz, DC Zimmerman, DS Straus, E Cernuda-Morollon, EE Farmer, EE Farmer, Henrik U. Stotz, HG Kang, HK Bryan, HU Stotz, HU Stotz, J Koster, J Mano, K Dueckershoff, KA Marrs, LJ Huang, M Zander, M Zander, M Zander, Maria Zoeller, Mark Zander, Markus Krischke, Martin J. Mueller, MJ Mueller, MS Biswas, N Kholod, N Taki, PJ Moos, RM Domingues, Rodrigo Franco, RS Wible, S Li, S Mueller, Simone Findling, Susanne Berger, SW Park, T Spector, TK Rudolph, W Chen, W Chen, Y Tada, Y Zhang, Z Mou   +51 more
core   +3 more sources

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

Animal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian, Longzhu Zhou, Xiaohui Feng, Jialu Shen, Xiaoping Du, Qingyu Zhao, Yuchang Qin, Junmin Zhang, Chaohua Tang   +8 more
wiley   +1 more source

Oxylipins in Aqueous Humor of Primary Open-Angle Glaucoma Patients

Biomolecules
Purpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass ...
Jianming Xu, Kewen Zhou, Changzhen Fu, Chong-Bo Chen, Yaru Sun, Xin Wen, Luxi Yang, Tsz-Kin Ng, Qingping Liu, Mingzhi Zhang   +9 more
doaj   +1 more source