Results 51 to 60 of about 13,057 (203)

Oxylipin profile in saliva from patients with cystic fibrosis reveals a balance between pro-resolving and pro-inflammatory molecules

Scientific Reports, 2022
Oxylipins are signaling molecules originated by fatty acids that modulate vascular and bronchial tone, bronchial secretion, cytokine production and immune cell activity.
Vincenzo Carnovale, Alice Castaldo, Alessandro Di Minno, Monica Gelzo, Paola Iacotucci, Anna Illiano, Gabriella Pinto, Giuseppe Castaldo, Angela Amoresano   +8 more
doaj   +1 more source

Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

Frontiers in Immunology, 2023
IntroductionPremature infants (PIs) are at risk of suffering necrotizing enterocolitis (NEC), and infants consuming human milk (HM) show a lower incidence than infants receiving formula.
Marta Gómez-Ferrer, Elena Amaro-Prellezo, Abel Albiach-Delgado, Isabel Ten-Domenech, Julia Kuligowski, Pilar Sepúlveda, Pilar Sepúlveda, Pilar Sepúlveda, Pilar Sepúlveda   +8 more
doaj   +1 more source

CYP450-derived oxylipins mediate inflammatory resolution [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance A number of lipid mediators are known to contribute to inflammatory resolution. Fatty acid metabolites of cytochrome P450 (CYP) enzymes are found in abundance; however, their roles in inflammatory resolution are not known.
Derek W. Gilroy, Matthew L. Edin, Roel P. H. De Maeyer, Jonas Bystrom, Justine Newson, Fred B. Lih, Melanie Stables, Darryl C. Zeldin, David Bishop-Bailey   +8 more
openaire   +4 more sources

Modern Methods of Sample Preparation for the Analysis of Oxylipins in Biological Samples

Molecules, 2019
Oxylipins are potent lipid mediators derived from polyunsaturated fatty acids, which play important roles in various biological processes. Being important regulators and/or markers of a wide range of normal and pathological processes, oxylipins are ...
Ivan Liakh, Alicja Pakiet, Tomasz Sledzinski, Adriana Mika   +3 more
doaj   +1 more source

Fungal and bacterial oxylipins are signals for intra- and inter-cellular communication within plant disease

Frontiers in Plant Science, 2022
Lipids are central at various stages of host–pathogen interactions in determining virulence and modulating plant defense. Free fatty acids may act as substrates for oxidizing enzymes [e.g., lipoxygenases (LOXs) and dioxygenases (DOXs)] that synthesize ...
Marzia Beccaccioli, Nicoletta Pucci, Manuel Salustri, Marco Scortichini, Marco Zaccaria, Babak Momeni, Stefania Loreti, Massimo Reverberi, Valeria Scala   +8 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Oxylipins in Aqueous Humor of Primary Open-Angle Glaucoma Patients

Biomolecules
Purpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass ...
Jianming Xu, Kewen Zhou, Changzhen Fu, Chong-Bo Chen, Yaru Sun, Xin Wen, Luxi Yang, Tsz-Kin Ng, Qingping Liu, Mingzhi Zhang   +9 more
doaj   +1 more source

Biologically Active Oxylipins from Enzymatic and Nonenzymatic Routes in Macroalgae

Marine Drugs, 2016
Marine algae are rich and heterogeneous sources of great chemical diversity, among which oxylipins are a well-recognized class of natural products. Algal oxylipins comprise an assortment of oxygenated, halogenated, and unsaturated functional groups and ...
Mariana Barbosa, Patrícia Valentão, Paula B. Andrade   +2 more
doaj   +1 more source

Serum levels of oxylipins in achilles tendinopathy: an exploratory study. [PDF]

PLoS ONE, 2015
BACKGROUND:Linoleic acid-derived oxidation products are found in experimental pain models. However, little is known about the levels of such oxylipins in human pain.
Sandra Gouveia-Figueira, Malin L Nording, Jamie E Gaida, Sture Forsgren, Håkan Alfredson, Christopher J Fowler   +5 more
doaj   +1 more source

Effects of elevated [CO2 ] on maize defence against mycotoxigenic Fusarium verticillioides. [PDF]

, 2014
Maize is by quantity the most important C4 cereal crop; however, future climate changes are expected to increase maize susceptibility to mycotoxigenic fungal pathogens and reduce productivity. While rising atmospheric [CO2 ] is a driving force behind the
Alborn, Hans T, Allen, Leon Hartwell, Christensen, Shawn, Dafoe, Nicole J, Huffaker, Alisa, Martins, Vitor F, Romero, Maritza, Schmelz, Eric A, Sims, James, Swerbilow, Jay, Teal, Peter EA, Vaughan, Martha M   +11 more
core   +2 more sources