Results 11 to 20 of about 25,401,718 (281)
P-Bodies React to Stress and Nonsense [PDF]
P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of “mRNA purgatory.” Bhattacharyya et al. (2006) reveal that normal mRNA
Bruno, Ivone, Wilkinson, Miles F.
core +4 more sources
General (p,q)-mixed projection bodies
In this article, the general (p,q)-mixed projection bodies are introduced. Then, some basic properties of the general (p,q)-mixed projection bodies are discussed, and the extreme values of volumes of the general (p,q)-mixed projection bodies and their ...
Feng Yibin, Zhou Yanping
doaj +2 more sources
Mean drift forces on arrays of bodies due to incident long waves [PDF]
The scattering of long water waves by an array of bodies is investigated using the method of matched asymptotic expansions. Two particular geometries are considered, these are a group of vertical cylinders extending throughout the depth and a group of ...
McIver, P
core +6 more sources
P-Bodies: Composition, Properties, and Functions. [PDF]
Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily composed of translationally repressed mRNAs and proteins related to mRNA decay, suggesting roles in post-transcriptional regulation. P-bodies are conserved in eukaryotic cells and exhibit properties of liquid droplets.
Luo Y, Na Z, Slavoff SA.
europepmc +4 more sources
Deadenylation and P-bodies. [PDF]
Deadenylation is the major step in triggering mRNA decay and results in mRNA translation inhibition in eukaryotic cells. Therefore, it is plausible that deadenylation also induces the mRNP remodeling required for formation of GW bodies or RNA processing bodies (P-bodies), which harbor translationally silenced mRNPs.
Chen CY, Shyu AB.
europepmc +4 more sources
RNA Granules: A View from the RNA Perspective
RNA granules are ubiquitous. Composed of RNA-binding proteins and RNAs, they provide functional compartmentalization within cells. They are inextricably linked with RNA biology and as such are often referred to as the hubs for post-transcriptional ...
Siran Tian +2 more
doaj +1 more source
Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
Exosomes may mediate cell-to-cell communication by transporting various proteins and nucleic acids to neighboring cells. Some protein and RNA cargoes are significantly enriched in exosomes.
Xiao-Man Liu, Liang Ma, Randy Schekman
doaj +1 more source
Stress granules, P-bodies and cancer. [PDF]
Cancer cells are exposed to adverse conditions in the tumor microenvironment, and utilize post-transcriptional control mechanisms to re-program gene expression in ways that enhance cell survival. Stress granules and processing bodies are RNA-containing granules that contribute to this process by modulating cellular signaling pathways, metabolic ...
Anderson P, Kedersha N, Ivanov P.
europepmc +4 more sources
Intracellular trafficking and dynamics of P bodies [PDF]
RNAs are exported from the nucleus to the cytoplasm, where they undergo translation and produce proteins needed for the cellular life cycle. Some mRNAs are targeted by different RNA decay mechanisms and thereby undergo degradation. The 5'-->3' degradation machinery localizes to cytoplasmic complexes termed P bodies (PBs). They function in RNA turnover,
Adva, Aizer, Yaron, Shav-Tal
openaire +2 more sources
More-than-leaky bodies: Existence as resistance
Bodies, where ‘normal’ functions like digestion and excretion are enabled through non-human infrastructure (tubes, bags, and pumps), are more-than-leaky.
Budworth, P., Larrington-Spencer, H.
core +4 more sources

