Results 41 to 50 of about 25,401,718 (281)

HAX-1: A Novel P-Body Protein [PDF]

DNA and Cell Biology, 2015
HAX-1, a multifunctional protein involved in the regulation of apoptosis, cell migration, and calcium homeostasis, binds the 3' untranslated region motifs of specific transcripts. This suggests that HAX-1 plays a role in post-transcriptional regulation, at the level of mRNA stability/transport or translation.
Valery, Zayat, Anna, Balcerak, Jaroslaw, Korczynski, Alicja, Trebinska, Juliusz, Wysocki, Elżbieta, Sarnowska, Mateusz, Chmielarczyk, Ewelina, Macech, Ryszard, Konopiński, Magdalena, Dziembowska, Ewa A, Grzybowska   +10 more
openaire   +2 more sources

Extremum of geometric functionals involving general L p $L_{p}$ -projection bodies

Journal of Inequalities and Applications, 2016
Following the discovery of general L p $L_{p}$ -projection bodies by Ludwig, Haberl and Schuster determined the extremum of the volume of the polars of this family of L p $L_{p}$ -projection bodies.
Weidong Wang, Jianye Wang
doaj   +1 more source

Microtubule disruption stimulates P-body formation [PDF]

RNA, 2007
Processing bodies (P-bodies) are subcellular ribonucleoprotein (RNP) granules that have been hypothesized to be sites of mRNA degradation, mRNA translational control, and/or mRNA storage. Importantly, P-bodies are conserved from yeast to mammals and contain a common set of evolutionarily conserved protein constituents.
Thomas J, Sweet, Brooke, Boyer, Wenqian, Hu, Kristian E, Baker, Jeff, Coller   +4 more
openaire   +2 more sources

White book on physical and rehabilitation medicine (PRM) in Europe. Chapter 5.The PRM organizations in Europe: Structure and activities

, 2018
In the context of the White Book of Physical and Rehabilitation Medicine (PRM) in Europe, this paper addresses the structure, organization and activities of PRM bodies in Europe.
Ceravolo Maria Gabriella, European Physical and Rehabilitation Medicine Bodies Alliance   +1 more
core   +1 more source

RNA-Binding Protein TAF15 Suppresses Toxicity in a Yeast Model of FUS Proteinopathy

Journal of Fungi
Mutations in an RNA-binding protein FUS are known to cause familial amyotrophic lateral sclerosis (ALS). Since this discovery, mutations in several other RNA-binding proteins (RBPs) have also been linked to ALS.
Elliott Hayden, Aicha Kebe, Shuzhen Chen, Abagail Chumley, Chenyi Xia, Widad El-Zein, Quan Zhong, Shulin Ju   +7 more
doaj   +1 more source

Regulation of processing body formation in the budding yeast "Saccharomyces cerevisiae" [PDF]

, 2014
The life cycle of mRNA, from transcription to decay, is a tightly regulated biological process. mRNA is an essential molecule that the cell utilizes to alter gene expression. Degradation is one process through which the cell can regulate mRNA levels.
Weidner, Julie
core   +1 more source

Relationship of GW/P-bodies with stress granules. [PDF]

Adv Exp Med Biol, 2013
Whereas P-bodies are intimately linked to the cytoplasmic RNA decay machinery, stress granules harbor stalled translation initiation complexes that accumulate upon stress-induced translation arrest. In this Chapter, we reflect on the relationship between P-bodies and stress granules.
Stoecklin G, Kedersha N.
europepmc   +4 more sources

RNA sequestration in P-bodies sustains myeloid leukaemia. [PDF]

Nat Cell Biol
Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and are often dysregulated in cancer. Here, we identified regulators of P-bodies as crucial vulnerabilities in acute myeloid leukaemia (AML) through genome-wide CRISPR screens in normal and malignant haematopoietic progenitors.
Kodali S, Proietti L, Valcarcel G, López-Rubio AV, Pessina P, Eder T, Shi J, Jen A, Lupión-Garcia N, Starner AC, Bartels MD, Cui Y, Sands CM, Planas-Riverola A, Martínez A, Velasco-Hernandez T, Tomás-Daza L, Alber B, Manhart G, Mayer IM, Kollmann K, Fatica A, Menendez P, Shishkova E, Rau RE, Javierre BM, Coon J, Chen Q, Van Nostrand EL, Sardina JL, Grebien F, Di Stefano B.   +31 more
europepmc   +5 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Xrn1 Exoribonuclease—An Intrinsic Marker of Yeast Population Growth

Frontiers in Bioscience-Elite
Background: Xrn1 exoribonuclease is the major mRNA degradation enzyme in Saccharomyces cerevisiae. In exponentially growing cells, Xrn1 is localised in the yeast cells and directs the degradation of mRNA molecules.
Tomas Grousl, Tomas Vomastek
doaj   +1 more source