Results 31 to 40 of about 25,401,718 (281)
Frontiers in Cell and Developmental Biology, 2021 The hypoxic microenvironment is beneficial to the metastasis but not to the proliferation of cancer cells. However, the mechanisms regarding to hypoxia differentially regulating cancer metastasis and proliferation are largely unknown.
Mingjiao Weng +20 more
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Mammalian stress granules and P bodies at a glance. [PDF]
J Cell Sci, 2020 ABSTRACT Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-based cellular compartments that assemble in response to stress. SGs and PBs form through liquid–liquid phase separation that is driven by high local concentrations of key proteins and RNAs, both of which dynamically shuttle between the granules
Riggs CL +3 more
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UV-induced fragmentation of Cajal bodies [PDF]
, 2006 The morphology and composition of subnuclear organelles, such as Cajal bodies (CBs), nucleoli, and other nuclear bodies, is dynamic and can change in response to a variety of cell stimuli, including stress.
Angus I. Lamond +7 more
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The Journal of Cell Biology, 2007 ![Graphic][1] Construction of P-bodies (white) stops in the absence of Edc3p (right). Putting together a P-body requires both building blocks and glue. [Decker et al.][2] now show that a yeast mRNA decapping activator protein contributes to both jobs: it forms part of the ...
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Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles
Microbial Cell Factories, 2011 Processing bodies (PBs) and stress granules (SGs) are two highly conserved cytoplasmic ribonucleoprotein foci that contain translationally repressed mRNAs together with proteins from the mRNA metabolism.
Díez Juana, Giménez-Barcons Mireia
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The Control of mRNA Decapping and P-Body Formation [PDF]
Molecular Cell, 2008 mRNA decapping is a critical step in eukaryotic cytoplasmic mRNA turnover. Cytoplasmic mRNA decapping is catalyzed by Dcp2 in conjunction with its coactivator Dcp1 and is stimulated by decapping enhancer proteins. mRNAs associated with the decapping machinery can assemble into cytoplasmic mRNP granules called processing bodies (PBs).
Franks, Tobias M., Lykke-Andersen, Jens
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Properties of Stress Granule and P-Body Proteomes [PDF]
Molecular Cell, 2019 Stress granules and P-bodies are cytosolic biomolecular condensates that dynamically form by the phase separation of RNAs and proteins. They participate in translational control and buffer the proteome. Upon stress, global translation halts and mRNAs bound to the translational machinery and other proteins coalesce to form stress granules (SGs ...
Ji-Young, Youn +6 more
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General L p $L_{p}$ -mixed chord integrals of star bodies
Journal of Inequalities and Applications, 2016 The notion of general mixed chord integrals of star bodies was introduced by Feng and Wang. In this paper, we extend the concept of the general mixed chord integrals to general L p $L_{p}$ -mixed chord integrals of star bodies.
Zhaofeng Li, Weidong Wang
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P Bodies and the Control of mRNA Translation and Degradation [PDF]
Molecular Cell, 2007 Recent results indicate that many untranslating mRNAs in somatic eukaryotic cells assemble into related mRNPs that accumulate in specific cytoplasmic foci referred to as P bodies. Transcripts associated with P body components can either be degraded or return to translation.
Parker, Roy, Sheth, Ujwal
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eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs
EMBO Reports, 2023 Maternal mRNAs are essential for protein synthesis during oogenesis and early embryogenesis. To adapt translation to specific needs during development, maternal mRNAs are translationally repressed by shortening the polyA tails.
Laura Lorenzo-Orts +8 more
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