Results 11 to 20 of about 736,547 (297)

Towards a revised nomenclature for P1 and P2 receptors [PDF]

open access: yesTrends in Pharmacological Sciences, 1997
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B. Fredholm   +7 more
openaire   +4 more sources

Purinergic signalling: past, present and future [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2009
The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
G. Burnstock
doaj   +1 more source

Characterisation of bovine leukocyte Ig-like receptors [PDF]

open access: yes, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC   +8 more
core   +4 more sources

The Potential of Purinergic Signaling to Thwart Viruses Including SARS-CoV-2

open access: yesFrontiers in Immunology, 2022
A long-shared evolutionary history is congruent with the multiple roles played by purinergic signaling in viral infection, replication and host responses that can assist or hinder viral functions.
Davide Ferrari   +4 more
doaj   +1 more source

The adenosinergic machinery in cancer: In-tandem insights from basic mechanisms to therapy

open access: yesFrontiers in Immunology, 2023
Extracellular adenosine (eADO) signaling has emerged as an increasingly important regulator of immune responses, including tumor immunity. eADO is mainly produced from extracellular ATP (eATP) hydrolysis.
Chifei Kang   +12 more
doaj   +1 more source

Vimentin Is an Attachment Receptor for Mycoplasma pneumoniae P1 Protein

open access: yesMicrobiology Spectrum, 2023
Mycoplasma pneumoniae is the most common pathogen causing respiratory tract infection, and the P1 protein on its adhesion organelle plays a crucial role during the pathogenic process. A variety of experiments, including enzyme-linked immunosorbent assay (ELISA), coimmunoprecipitation, adhesion, and adhesion inhibition assay ...
Kailan Peng   +7 more
openaire   +2 more sources

ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Receptor Activation by ATP Through Rapid and Localized Generation of Adenosine by Ecto-nucleotidases

open access: yesJournal of Pharmacological Sciences, 2004
Extracellular ATP is now recognized as a neurotransmitter or neuromodilator in the nervous system, producing diverse physiological effects by activating multiple P2 receptors.
Isao Matsuoka, Satoko Ohkubo
doaj   +1 more source

Prenatal exposure to valproic acid induces alterations in the expression and activity of purinergic receptors in the embryonic rat brain

open access: yesFolia Neuropathologica, 2022
Purinergic signalling is involved in the control of several processes related to brain development, such as neurogenesis and gliogenesis, migration and differentiation of neuronal precursors, synaptogenesis and synaptic elimination to achieve a fully ...
Lidia Babiec   +2 more
doaj   +1 more source

Pharmacological and Molecular Characterisation of P2Y Receptors in Endothelial and Epithelial Cells [PDF]

open access: yes, 2007
Submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyIn light of the significant modulation of receptor activity previously shown by a peptide (designated L247), designed to mimic ...
D’Souza, Vijay Kenneth
core   +3 more sources

Purinergic signaling: Diverse effects and therapeutic potential in cancer

open access: yesFrontiers in Oncology, 2023
Regardless of improved biological insights and therapeutic advances, cancer is consuming multiple lives worldwide. Cancer is a complex disease with diverse cellular, metabolic, and physiological parameters as its hallmarks.
Jasmeet Kaur, Sanchit Dora
doaj   +1 more source

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