Results 21 to 30 of about 736,547 (297)

Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]

, 2000
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
B. F. King, Burnstock, G., Wildman, Scott S.P., Townsend-Nicholson, A., Spyer, K. M., King, B F, A. Townsend-Nicholson, Thomas, T., G. Burnstock, Wildman, S. S., Thomas, T, King, B. F., Townsend-Nicholson, A, Burnstock, G, S. S. Wildman, Spyer, K M, T. Thomas, K. M. Spyer   +17 more
core   +1 more source

Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders

Frontiers in Pharmacology, 2017
Extracellular nucleosides and nucleotides, such as adenosine and adenosine triphosphate (ATP), are involved in many physiological and pathological processes in adipose tissue (AT).
Marco Tozzi, Ivana Novak
doaj   +1 more source

BACL is a novel brain-associated, non-NKC-encoded mammalian C-type lectin-like receptor of the CLEC2 family [PDF]

, 2013
Natural Killer Gene Complex (NKC)–encoded C-type lectin-like receptors (CTLRs) are expressed on various immune cells including T cells, NK cells and myeloid cells and thereby contribute to the orchestration of cellular immune responses.
Mittelbronn, Michel Guy André, Michel Mittelbronn, Olga Lysenko (420632), Alexander Steinle (254716), Schulte, Dorothea, Lysenko, Olga, Dorothea Schulte, Steinle, Alexander, Alexander Steinle, Dorothea Schulte (420633), Olga Lysenko, Michel Mittelbronn (307400)   +11 more
core   +1 more source

Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival

Frontiers in Cellular Neuroscience, 2019
Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP).
Shelly C. Y. Lin, Peter R. Thorne, Gary D. Housley, Srdjan M. Vlajkovic   +3 more
doaj   +1 more source

Eosinophils and Purinergic Signaling in Health and Disease

Frontiers in Immunology, 2020
Eosinophils are major effector cells against parasites, fungi, bacteria, and viruses. However, these cells also take part in local and systemic inflammation, which are central to eczema, atopy, rhinitis, asthma, and autoimmune diseases.
Davide Ferrari, Marta Vuerich, Fabio Casciano, Maria Serena Longhi, Elisabetta Melloni, Paola Secchiero, Andreas Zech, Simon C. Robson, Tobias Müller, Marco Idzko   +9 more
doaj   +1 more source

Extracellular ATP and its derivatives provide spatiotemporal guidance for bone adaptation to wide spectrum of physical forces

Bone Reports, 2022
ATP is a ubiquitous intracellular molecule critical for cellular bioenergetics. ATP is released in response to mechanical stimulation through vesicular release, small tears in cellular plasma membranes, or when cells are destroyed by traumatic forces ...
Chrisanne Dsouza, Mahmoud S. Moussa, Nicholas Mikolajewicz, Svetlana V. Komarova   +3 more
doaj   +1 more source

Purinergic Regulation of Food and Fat Intakes in Broiler’s Central Nervous System [PDF]

Iranian Journal of Veterinary Medicine, 2021
BACKGROUND: Adenosine has many physiological roles in the brain, and in rodents, it changes food intake when applied centrally. OBJECTIVES: We investigated the effect of central injection of the purine molecule adenosine on both food and fat intakes in ...
Sahel Motaghi, Hossein Jonaidi, Alireza Bashiri, Samaneh Nouri Gooshki   +3 more
doaj   +1 more source

G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions [PDF]

Purinergic Signalling, 2012
The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors (ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and pyrimidine mono- and dinucleotides) has recently advanced significantly leading to selective ligands.
Kenneth A, Jacobson, Ramachandran, Balasubramanian, Francesca, Deflorian, Zhan-Guo, Gao   +3 more
openaire   +2 more sources

Purinergic signaling in the modulation of redox biology

Redox Biology, 2021
Purinergic signaling is a cell communication pathway mediated by extracellular nucleotides and nucleosides. Tri- and diphosphonucleotides are released in physiological and pathological circumstances activating purinergic type 2 receptors (P2 receptors ...
Luiz Eduardo Baggio Savio, Raíssa Leite-Aguiar, Vinícius Santos Alves, Robson Coutinho-Silva, Angela T.S. Wyse   +4 more
doaj   +1 more source

The Effects of Selective Serotonin-Reuptake Inhibitor on Visual Evoked Potential in Rats

Journal of Pharmacological Sciences, 2004
The present study was undertaken to clarify the effects of selective serotonin-reuptake inhibitors (SSRIs) on visual evoked potential (VEP) in rats. To elucidate the mechanism of action of SSRIs, some serotonin (5-HT) agonists were used.
Yoshihiro Iwamura, Yoko Fujii, Chiaki Kamei   +2 more
doaj   +1 more source