Results 61 to 70 of about 3,153 (172)
Hypothesis: Clues From Mammalian Hibernation for Treating Patients With Anorexia Nervosa
This hypothesis is that anorexia nervosa (AN) is a biologically driven disorder, and mammalian hibernation may offer clues to its pathogenesis. Using this approach, this hypothesis offers suggestions for employing heart rate variability as an early ...
Barbara Scolnick
doaj +1 more source
This study presents a multimatrix untargeted metabolomics analysis of fecal, plasma, and urine samples from individuals at high risk for pancreatic cancer development. Integrated multivariate and cofactor‐adjusted models were applied to characterize cross‐matrix metabolomic associations, incorporating pancreatic magnetic resonance imaging data, sex ...
Vladyslav Dovhalyuk +6 more
wiley +1 more source
It is commonly accepted that some form of skin barrier dysfunction is present in canine atopic dermatitis (AD), one of the most common cutaneous pruritic inflammatory diseases of dogs.
Roberto Chiocchetti +7 more
doaj +1 more source
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin +3 more
wiley +1 more source
The aim of this study was to compare concentrations of endogenous N-acylethanolamine (NAE) lipid mediators—palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and anandamide (AEA)—in fresh, decontaminated, cryopreserved, and freeze-dried amniotic ...
Vladimir Vrkoslav +7 more
doaj +1 more source
Palmitoylethanolamide (PEA) as a Potential Therapeutic Agent in Alzheimer’s Disease [PDF]
N-Palmitoylethanolamide (PEA) is a non-endocannabinoid lipid mediator belonging to the class of the N-acylethanolamine phospolipids and was firstly isolated from soy lecithin, egg yolk, and peanut meal. Either preclinical or clinical studies indicate that PEA is potentially useful in a wide range of therapeutic areas, including eczema, pain, and ...
Sarah Beggiato +7 more
openaire +4 more sources
Since autacoids are short‐lived bioactive substances that act near their site of biosynthesis, the biased activities of prostanoid metabolites may have significant physiological implications with regard to the newly defined and/or re‐acknowledged as unique and novel nongenomic feedback mechanisms, which may be one of very important roles of prostanoids
Hiromichi Fujino, Keijo Fukushima
wiley +1 more source
Molecular Targets of Fatty Acid Ethanolamides in Asthma
Asthma is a common allergic pathology of the respiratory tract that requires the study of mechanisms underlying it, due to severe forms of the disease, which are refractory to therapy.
Oxana Kytikova +4 more
doaj +1 more source
Chronic orofacial pain management: A narrative review of pharmacological and promising therapy
Chronic orofacial pain is a multifactorial stressful condition. It devastates patients’ lives and depletes medical and dental services. Assertion of a particular effective pharmacological treatment is difficult due to psychological involvement and ...
Malath Azeez Al-saadi
doaj +1 more source
Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice [PDF]
We have studied the effect of palmitoylethanolamide (PEA, 2.5 – 30 mg kg−1, i.p.) on upper gastrointestinal transit in control mice and in mice with chronic intestinal inflammation induced by croton oil. PEA significantly and dose‐dependently decreased intestinal transit.
CAPASSO, RAFFAELE +6 more
openaire +4 more sources

