Results 1 to 10 of about 5,442 (184)
A UiO-66-NH2 MOF/PAMAM Dendrimer Nanocomposite for Electrochemical Detection of Tramadol in the Presence of Acetaminophen in Pharmaceutical Formulations [PDF]
Biosensors, 2023 In this work, we prepared a novel electrochemical sensor for the detection of tramadol based on a UiO-66-NH2 metal–organic framework (UiO-66-NH2 MOF)/third-generation poly(amidoamine) dendrimer (G3-PAMAM dendrimer) nanocomposite drop-cast onto a glassy ...
Fariba Garkani Nejad +2 more
doaj +2 more sources
The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs [PDF]
Molecules, 2018 The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu +9 more
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PAMAM dendrimer - cell membrane interactions
Advances in Colloid and Interface Science, 2018 PAMAM dendrimers have been conjectured for a wide range of biomedical applications due to their tuneable physicochemical properties. However, their application has been hindered by uncertainties in their cytotoxicity, which is influenced by dendrimer generation (i.e.
Robert M Richardson, Wuge Briscoe
exaly +5 more sources
Molecules, 2021 We have developed a convenient and selective method for the detection of Gram-positive bacteria using a ditopic poly(amidoamine) (PAMAM) dendrimer probe.
Ayame Mikagi +6 more
doaj +1 more source
High Fluorescent Porphyrin-PAMAM-Fluorene Dendrimers [PDF]
Molecules, 2015 Two new classes of dendrimers bearing 8 and 32 fluorene donor groups have been synthesized. The first and second generations of these porphyrin-PAMAM-fluorene dendrimers were characterized by 1H-NMR, 13C-NMR, FTIR, UV-vis spectroscopy, elemental analyses and MALDI-TOF mass spectrometry.
Garfias-Gonzalez, Karla +6 more
openaire +3 more sources
Inverse Polyamidoamine (i‐PAMAM) Dendrimer Antimicrobials
Helvetica Chimica Acta, 2023 AbstractHere we redesigned the branches of polyamidoamine (PAMAM) dendrimers by moving the amide carbonyl group on the other side of the amide nitrogen atom, transforming the β‐alaninyl‐amidoethylamine branch, which easily undergoes retro‐Michael reactions and renders PAMAMs intrinsically unstable, into a more stable glycyl‐amidopropylamine branch. The
Bonvin, Etienne, Reymond, Jean-Louis
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Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy
Molecules, 2023 Lung cancer is the main cause of cancer-related mortality globally. Erlotinib is a tyrosine kinase inhibitor, affecting both cancerous cell proliferation and survival.
Wafa K. Fatani +9 more
doaj +1 more source
Paramagnetic NMR investigation of dendrimer-based host-guest interactions. [PDF]
PLoS ONE, 2013 In this study, the host-guest behavior of poly(amidoamine) (PAMAM) dendrimers bearing amine, hydroxyl, or carboxylate surface functionalities were investigated by paramagnetic NMR studies.
Fei Wang, Naimin Shao, Yiyun Cheng
doaj +1 more source
Pharmaceutics, 2022 Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and ...
Saghir Akhtar +3 more
doaj +1 more source
New Dendrimers: Synthesis and Characterization of POPAM−PAMAM Hybrid Dendrimers [PDF]
Macromolecules, 2008 Recently developed multifunctional cancer therapeutic nano-device production is based on poly(amidoamine) PAMAM generation 5 (G5) dendrimer as a carrier 1-5. Scale up synthesis of this nano-device is limited because of long reaction sequence (12 reaction steps) and long and not easy work up of the products after each reaction step.
István J, Majoros +3 more
openaire +2 more sources