Results 11 to 20 of about 5,442 (184)
Molecules, 2018 Clinical applications of many small molecules are limited due to poor solubility and lack of controlled release besides lack of other desirable properties.
Daniel M. Shadrack +4 more
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Comparative Evaluation of Lipofectamine and Dendrimer for Transfection of Short RNA Into Human T47D and MCF-10A Cell Lines [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Non-viral transfection approaches are extensively used in cancer therapy. The future of cancer therapy lies on targeted and efficient drug/gene delivery.
Zohreh Jahanafrooz +2 more
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Development of Tat-Conjugated Dendrimer for Transdermal DNA Vaccine Delivery
Journal of Pharmacy & Pharmaceutical Sciences, 2016 PURPOSE: In order to enhance cellular uptake and to facilitate transdermal delivery of DNA vaccine, polyamidoamine (PAMAM) dendrimers conjugated with HIV transactivator of transcription (TAT) was developed.
Azadeh Bahadoran +4 more
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Label-Free Detection of Saxitoxin with Field-Effect Device-Based Biosensor
Nanomaterials, 2022 Saxitoxin (STX) is a highly toxic and widely distributed paralytic shellfish toxin (PSP), posing a serious hazard to the environment and human health. Thus, it is highly required to develop new STX detection approaches that are convenient, desirable, and
Najeeb Ullah +5 more
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Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form [PDF]
Pharmaciana, 2018 Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum ...
Rahmah Elfiyani +2 more
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Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates
International Journal of Pharmaceutical Investigation, 2014 The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela +2 more
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Journal of Nanobiotechnology, 2021 Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear.
Jie Zhang +7 more
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Intrinsic Fluorescence of PAMAM Dendrimers—Quenching Studies [PDF]
Polymers, 2018 Intrinsic, non-traditional fluorescence of polyamidoamine (PAMAM) dendrimers that do not possess classical fluorophores has been attracting considerable interest for the last decade. Many hypotheses regarding the source of the fluorescence have appeared, but some of them are still disputable.
Malgorzata Konopka +2 more
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Toxicity of Hexyl Acrylate Modified PAMAM Dendrimer [PDF]
Trends in Pharmaceutical Sciences, 2018 The aim of this study was to evaluate the effect of the hexyl acrylate conjugated polyamidoamine (PAMSM) dendrimer on different cell lines in the presence and absence of serum.
Mohammad Ashkan Naderian +3 more
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Journal of Saudi Chemical Society, 2015 In this study, poly(amidoamine) (PAMAM) G-2 dendrimer was used for jute yarn. Fourier transform infrared spectroscopy (FT-IR) revealed that all carbonyl groups of jute fibers reacted with amino groups of polyamidoamine dendrimers.
Ali Akbar Zolriasatein +3 more
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