Results 51 to 60 of about 5,442 (184)

Chemistry of Secondary Metabolites (Production, Properties, Biological Activity, etc.): Solubility Study of the Interaction between Pamam G-3 Dendrimer and 5 Fluorouracil in Aqueous Solution

International Journal of Secondary Metabolite, 2016
Poly(amidoamine) dendrimers (PAMAM) are polymeric macromolecules that can find their use as carriers of small ligand molecules such as cosmetics and drugs.
B. PALECZ, A. BUCZKOWSKI, L. B. ZAVODNIK   +2 more
doaj  

Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein

Results in Physics, 2018
In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins.
Nur Alia Sheh Omar, Yap Wing Fen, Jaafar Abdullah, Nur Ain Asyiqin Anas, Nur Syahira Md Ramdzan, Mohd Adzir Mahdi   +5 more
doaj   +1 more source

Engineered Optical Fibers for Deep‐Tissue Applications

Advanced Optical Materials, Volume 14, Issue 10, 13 March 2026.
This review establishes a foundational framework for designing optical fibers for deep‐tissue medicine. It systematically links material innovations like polymers and hydrogels with structural paradigms to enable state‐of‐the‐art diagnostics, including endoscopy and biosensing, and targeted therapeutics, guiding future clinical translation.
Yuzhen Li, Siyang Zheng, Wenzhao Li, Kai Chen, Tianting Zhong, Chi Man Woo, Weiran Pang, Chuqi Yuan, Xiaozhou Xiao, Xianguang Yang, Long Jin, Xiang Qian, Qiyao Tan, Changyuan Yu, Liwei Liu, Junle Qu, Puxiang Lai   +16 more
wiley   +1 more source

Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture

Molecules, 2018
Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable physicochemical features, making them promising candidates for targeted drug delivery in the central nervous system (CNS).
Yossef Alnasser, Siva P. Kambhampati, Elizabeth Nance, Labchan Rajbhandari, Shiva Shrestha, Arun Venkatesan, Rangaramanujam M. Kannan, Sujatha Kannan   +7 more
doaj   +1 more source

Remodeling the Inflammatory Microenvironment: Nanomaterial‐Based Targeted Strategies for Systemic Lupus Erythematosus and Lupus Nephritis

Small Science, Volume 6, Issue 3, March 2026.
Current treatments for severe lupus nephritis are limited by side effects due to poor drug targeting. This review explores how smart nanomaterials—like liposomes and biomimetic carriers—can precisely deliver drugs to overactive immune cells and the kidneys. These nanotherapeutics enhance efficacy, reduce toxicity, and enable combination strategies. The
Cheng Zhou, Jiayi Li, Jian Zhang, Haifeng Wang, Haitao Lu, Shunlai Shang, Wenge Li   +6 more
wiley   +1 more source

Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum

Scientific Reports, 2020
In this study, the use of dendrimer-coated carbon nanotubes (CNTs) as a delivery vehicle for dsRNA was assessed in Tribolium castaneum. Exposure to low dosages of polyamidoamine dendrimer carbon nanotubes (PAMAM-CNTs) did not affect T.
Catriona H. Edwards, Craig R. Christie, Andrea Masotti, Antonella Celluzzi, Andrea Caporali, Ewan M. Campbell   +5 more
doaj   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, Volume 13, Issue 10, 18 February 2026.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

PAMAM dendrimers based co-delivery of methotrexate and berberine for targeting of Hela cancer cells

Toxicology Reports
Polyamidoamine dendrimer (PAMAM) is a class of synthetic macromolecular polymers for targeted drug delivery. PAMAM dendrimers are characterized by a pure defined structure, adjustable nanoscale dimensions, mono-dispersity, and versatile surface ...
Hossein Majidzadeh, Mostafa Araj-Khodaei, Ayuob Aghanejad, Maryam Ghaffari, Amir Jafari, Forough Jenanifard, Jafar Ezzati Nazhad Dolatabadi, Hashem Andishmand, Michael R. Hamblin   +8 more
doaj   +1 more source

Effect of methotrexate conjugated PAMAM dendrimers on the viability of MES-SA uterine cancer cells

Journal of Pharmacy and Bioallied Sciences, 2014
The aim of this work was to synthesize methotrexate (MTX)-polyamidoamine (PAMAM) dendritic nanoconjugates and to study their effect on cell viability in uterine sarcoma cells.
Samreen Khatri, Nandita G Das, Sudip K Das   +2 more
doaj   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source