Results 91 to 100 of about 5,309 (159)
Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation
Molecular & Cellular Oncology, 2019 Apoptosis can promote inflammation by triggering activation of the NLRP3 inflammasome (NLR family, pyrin domain containing 3). However, the molecular mechanisms regulating these processes are ill-defined.
Benjamin Demarco +2 more
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Pannexin channels in inflammation and tumorigenesis
Frontiers in Cell and Developmental BiologyPannexin (Panx) channels are oligomeric heptamers of PANX proteins, comprising Panx1, Panx2 and Panx3. These channels facilitate the extracellular release of signaling molecules up to 1.5 kDa in size, including adenosine triphosphate (ATP), amino acids ...
Mengmeng Jiang +5 more
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Connexins, Pannexins, and Epilepsy
Abstract Connexins are proteins that form gap junctions which “connect” cells together, permitting the passage of small molecules and electricity. Since epilepsy is thought of as a disease of neuronal hypersynchrony, it is natural to consider these molecules with the gap junctions they form as playing a significant role in epilepsy. Over
Liang Zhang +2 more
openaire +1 more source
Editorial: Single membrane channels formed by connexins or pannexins: focus on the nervous system
Frontiers in Cellular Neuroscience, 2015 Juan Andrés Orellana
doaj +1 more source
Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease. [PDF]
Purinergic SignalIvanov V +9 more
europepmc +1 more source
Pannexins in the heart: cell-specific expression and contributions to disease. [PDF]
Cell Tissue ResRenton MC +7 more
europepmc +1 more source
Type II Cells in the Human Carotid Body Display P2X7 Receptor and Pannexin-1 Immunoreactivity. [PDF]
BiomoleculesAnache M +10 more
europepmc +1 more source
Pannexin-1 is present in a subpopulation of bovine milk-derived small extracellular vesicles. [PDF]
Cell Tissue ResAmin MR +6 more
europepmc +1 more source