Results 81 to 90 of about 5,491 (175)
Relevance of Gap Junctions and Large Pore Channels in Traumatic Brain Injury
Frontiers in Physiology, 2014 In case of traumatic brain injury (TBI), occurrence of central nervous tissue damage is frequently aligned with local modulations of neuronal and glial gap junction channel expression levels.
Nora eProchnow
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Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020 Introduction: Diabetes is one of the most common metabolic diseases that is associated with high blood sugar and can cause disorders of the central nervous system.
Mohammad Rami +3 more
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Investigation of olfactory function in a Panx1 knock out mouse model
Frontiers in Cellular Neuroscience, 2014 Pannexin 1 (Panx1), the most extensively investigated member of a channel-forming protein family, is able to form pores conducting molecules up to 1.5 kDa, like ATP, upon activation.
Stefan eKurtenbach +7 more
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Physiological ReportsWe sought to determine the physiological relevance of pannexin/purinergic‐dependent signaling in mediating conducted vasodilation elicited by capillary stimulation through skeletal muscle contraction.
Iain R. Lamb +2 more
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Molecular pathways of pannexin1-mediated neurotoxicity
Frontiers in Physiology, 2014 Pannexin1 (Panx1) forms nonselective membrane channels, structurally similar to gap junction hemichannels, that is permeable to ions, nucleotides and other small molecules below 900 Da. Panx1 activity is implicated in paracrine signaling and inflammasome
Valery I. Shestopalov +4 more
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IMPLICATIONS OF PANNEXIN 1 AND PANNEXIN 3 IN KERATINOCYTE DIFFERENTIATION [PDF]
, 2009 Pannexin (Panx) 1 and Panx3 are integral membrane proteins with sequence homology to the invertebrate gap junctions, innexins, and are expressed in mammalian skin. Panxs form functional single-membrane channels but their importance in regulating cellular function is poorly understood.
openaire
A taste for ATP: neurotransmission in taste buds
Frontiers in Cellular Neuroscience, 2013 Not only is ATP a ubiquitous source of energy but it is also used widely as an intercellular signal. For example, keratinocytes release ATP in response to numerous external stimuli including pressure, heat and chemical insult. The released ATP activates
Thomas E. Finger, Sue C Kinnamon
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Spermatogenesis, 2011 Gap junctions and connexins are critical for coordinating cellular functions in complex epithelia. In recent years there has been increased interest in understanding the regulation and function of gap junctions in both the testis and epididymis. Studies in transgenic mice in which connexin 43 (Cx43) is mutated or is knocked down only in Sertoli cells ...
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A throwback on 25 years in pannexin research
Current Opinion in ImmunologyCellular channels consisting of pannexins facilitate signaling between the intracellular and extracellular environment. In this respect, pannexin channel opening serves as a pivotal trigger for both inflammatory processes and cell death. While pannexin channels also contribute to normal physiological functions, their roles in pathological mechanisms ...
Daan Peeters +2 more
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Editorial: Single membrane channels formed by connexins or pannexins: focus on the nervous system
Frontiers in Cellular Neuroscience, 2015 Juan Andrés Orellana
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