Results 91 to 100 of about 7,051 (198)
Frontiers in Molecular Neuroscience, 2017 Background: Accumulating evidence suggests that neuroinflammation plays a critical role in early brain injury after subarachnoid hemorrhage (SAH). Pannexin-1 channels, as a member of gap junction proteins located on the plasma membrane, releases ATP ...
Ling-Yun Wu +13 more
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Measuring the amount of the channel protein pannexin 1 across neuronal development [PDF]
, 2022 My Presentation is on Pannexin 1 an ATP channel protein in the brain. I have analyzed both the theoretical side as well as the practical side of this protein.
Irwin, Eamonn
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Involvement of gap junction channels in the pathophysiology of migraine with aura
Frontiers in Physiology, 2014 Migraine is a common, recurrent and disabling primary headache disorder with a genetic component which affects up to 20 % of the population. One third of all patients with migraine experiences aura, a focal neurological disturbance that manifests itself ...
Denis eSarrouilhe +2 more
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A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP
, 2009 Pannexin 1 forms a large membrane channel that, based on its biophysical properties and its expression pattern, is a prime candidate to represent an ATP release channel. Pannexin 1 channel activity is potentially deleterious for cells as indicated by its
Dahl, Gerhard, Qiu, Feng
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Innexins: Expression, Regulation, and Functions
Frontiers in Physiology, 2018 The innexin (Inx) proteins form gap junction channels and non-junctional channels (named hemichannels) in invertebrates. These channels participate in cellular communication playing a relevant role in several physiological processes.
Juan Güiza +4 more
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, 2022 Background: In preclinical models, the pannexin-1 channel has been shown to be involved in blood pressure regulation through an effect on peripheral vascular resistance. Pannexin-1 releases ATP, which can activate constrictive purinergic receptors on the
Gliemann, Lasse +5 more
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Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation
Molecular & Cellular Oncology, 2019 Apoptosis can promote inflammation by triggering activation of the NLRP3 inflammasome (NLR family, pyrin domain containing 3). However, the molecular mechanisms regulating these processes are ill-defined.
Benjamin Demarco +2 more
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Pannexin-1 in silico modeling towards physiological and pathological functioning
, 2020 The transmembrane pore protein Pannexin-1 (Panx1) forms channels allowing the release of purine nucleotides and participates in processes related to purinergic signaling, including blood pressure regulation, apoptotic cell clearance, and neuropathic pain.
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, 2022 Introduction: Regular exercise training reduces arterial blood pressure but the underlying mechanisms are unclear. Here, we evaluated the potential involvement of Pannexin 1, an ATP releasing channel, in the blood pressure-reducing effect of training ...
Gliemann, Lasse +21 more
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Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020 Introduction: Diabetes is one of the most common metabolic diseases that is associated with high blood sugar and can cause disorders of the central nervous system.
Mohammad Rami +3 more
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