Results 101 to 110 of about 6,586 (171)

Pannexin-1 in Human Lymphatic Endothelial Cells Regulates Lymphangiogenesis

, 2018
International audienceThe molecular mechanisms governing the formation of lymphatic vasculature are notyet well understood. Pannexins are transmembrane proteins that form channels which allow fordiffusion of ions and small molecules (
Clarhaut, Jonathan, Claire Simonneau, Mesnil, Marc, Marc Mesnil, Cronier, Laurent, Golthlay Denet, Monvoisin, Arnaud, Arnaud Monvoisin, Laurent Cronier, Balandre, Claire, Annie-Claire Balandre, Denet, Golthlay, Jonathan Clarhaut, Simonneau, Claire, Boucher, Jonathan, Jonathan Boucher   +15 more
core   +1 more source

Physiological roles of gap junction protein pannexin

, 2007
Open, unopposed gap junction hemichannels can be deleterious to a cell due to their large conductance and permeation properties. But brief openings of the hemichannels, triggered by a variety of stimuli, may be of physiological importance for cells.
Locovei, Silviu
core  

Probenecid, a gout remedy, inhibits pannexin 1 channels

, 2008
Probenecid is a well-established drug for the treatment of gout and is thought to act on an organic anion transporter, thereby affecting uric acid excretion in the kidney by blocking urate reuptake.
Locovei, Silviu, Dahl, Gerhard, Gerhard Dahl, Silverman, William, William Silverman, Silviu Locovei   +5 more
core   +1 more source

Editorial: Single membrane channels formed by connexins or pannexins: focus on the nervous system

Frontiers in Cellular Neuroscience, 2015
Juan Andrés Orellana
doaj   +1 more source

The role of pannexin 1 in the purinergic regulation of synaptic transmission in mouse motor synapses

, 2017
The role of pannexin 1 in the release to the extracellular space of ATP/adenosine modulating the acetylcholine (ACh) secretion was studied in mouse diaphragm motor synapses. Using neuromuscular preparations obtained from wild-type and pannexin-1 knockout
A. E. Gaydukov, V. I. Shestopalov, Shestopalov, V, Gaydukov, A, A. S. Miteva, O. P. Balezina, Miteva, A, Balezina, O   +7 more
core   +1 more source

Reduced Serum Pannexin-1 Levels in Obstructive Sleep Apnea and Their Association with Nocturnal Hypoxemic Burden. [PDF]

J Clin Med
Canlı ET, Öztürk Ö, Türkmen Kaya H, Şirin FB, Gümüşcan D, Aydın T, Karaibrahimoğlu A.   +6 more
europepmc   +1 more source

Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease. [PDF]

Purinergic Signal
Ivanov V, Wu A, Crocetti L, Meng Z, Shrestha-Maskey P, Liao TD, Adrianto I, Guerrini G, Ortiz PA, Pavlov TS.   +9 more
europepmc   +1 more source

Pannexins in the heart: cell-specific expression and contributions to disease. [PDF]

Cell Tissue Res
Renton MC, Sedovy MW, Reynolds A, Hoch A, Roberts K, Sarmiento R, Toler C, Johnstone SR.   +7 more
europepmc   +1 more source

Pannexin-1-mediated ATP signaling as a driver of immune communication and chronic inflammation in HIV infection. [PDF]

Front Immunol
Kaufman EK, Swartz TH.
europepmc   +1 more source

Type II Cells in the Human Carotid Body Display P2X7 Receptor and Pannexin-1 Immunoreactivity. [PDF]

Biomolecules
Anache M, Méndez R, García-Suárez O, Cuendias P, Martínez-Barbero G, Alba E, Cobo T, Suazo I, Vega JA, Martín-Cruces J, García-Mesa Y.   +10 more
europepmc   +1 more source