Pannexins in the musculoskeletal system: new targets for development and disease progression
Bone ResearchDuring cell differentiation, growth, and development, cells can respond to extracellular stimuli through communication channels. Pannexin (Panx) family and connexin (Cx) family are two important types of channel-forming proteins.
Yan Luo +4 more
doaj +1 more source
Hemichannels; from the molecule to the function
Frontiers in Physiology, 2014 Mauricio Antonio Retamal, Juan C Saez
doaj +1 more source
Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons. [PDF]
Int J Mol Sci, 2022 Lucero CM +9 more
europepmc +1 more source
Pannexins in the heart: cell-specific expression and contributions to disease. [PDF]
Cell Tissue ResRenton MC +7 more
europepmc +1 more source
Can the Tumor Microenvironment Alter Ion Channels? Unraveling Their Role in Cancer. [PDF]
Cancers (Basel)Gentile R +3 more
europepmc +1 more source
Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage. [PDF]
Biology (Basel), 2021 Zhang Y +6 more
europepmc +1 more source
Pannexin 3, but not pannexin 1 is an important pro-catabolic mediator in osteoarthritis. [PDF]
Osteoarthritis and Cartilage, 2016 Moon, P. +3 more
openaire +1 more source
Panx1 and drug discovery: from non-specific inhibitors to tailored drug compounds. [PDF]
Cell Tissue ResKohr M, Meier C.
europepmc +1 more source
Role of pannexins in vasculature
Pannexins are newly discovered proteins that were first discovered by Panchin in 2000. The pannexin family has three isomers, i.e. pannexin-1, pannexin-2, and pannexin-3.
Habib, Alaa
core
Identification and classification of ion channels across the tree of life provide functional insights into understudied CALHM channels. [PDF]
ElifeTaujale R +9 more
europepmc +1 more source