The destructive citrus pathogen, 'Candidatus Liberibacter asiaticus' encodes a functional flagellin characteristic of a pathogen-associated molecular pattern. [PDF]
Huanglongbing (HLB) is presently the most devastating citrus disease worldwide. As an intracellular plant pathogen and insect symbiont, the HLB bacterium, 'Candidatus Liberibacter asiaticus' (Las), retains the entire flagellum-encoding gene cluster in ...
Huasong Zou +5 more
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Do Mast Cells Contribute to the Antifungal Host Defense?
The fungal kingdom includes a group of microorganisms that are widely distributed in the environment, and therefore the exposure to them is almost constant.
Paulina Żelechowska +3 more
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Role of Translocation of Pathogen-Associated Molecular Patterns in Sepsis [PDF]
<i>Background/Aim:</i> Unlike animals, the incidence of bacterial translocation and its clinical significance remain to be determined in humans, which may be due to the lack of accurate methods to confirm and monitor bacterial translocation. The literature on the consequences of novel insights of bacterial translocation was reviewed.
Hironori, Tsujimoto +2 more
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Helicobacter pylori Pathogen-Associated Molecular Patterns: Friends or Foes?
Microbial infections are sensed by the host immune system by recognizing signature molecules called Pathogen-Associated Molecular Patterns—PAMPs. The binding of these biomolecules to innate immune receptors, called Pattern Recognition Receptors (PRRs), alerts the host cell, activating microbicidal and pro-inflammatory responses.
Eletto, Daniela +5 more
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Due to the global crisis caused by the dramatic rise of drug resistance among Gram-negative bacteria, there is an urgent need for a thorough understanding of the pathogenesis of infections of such an etiology.
Karolina Sidor, Tomasz Skirecki
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Damage- and Pathogen-Associated Molecular Patterns and Alarmins: Keys to Sepsis? [PDF]
The concept that sepsis is the result of an uncontrolled inflammatory response of the host’s innate immune system towards invading pathogens has recently been challenged. Evidence is accumulating that, in addition, host-derived alarm molecules are released during sepsis- and trauma-associated cell death, thus triggering the host’s immune response.
Denk, S. +2 more
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Pathogen-Associated Molecular Pattern-Triggered Immunity: Veni, Vidi…?
For many years, plant pathology was divided into two schools of thought. It was clear that purified molecules or crude extracts from microbes or plants (referred to as general elicitors) could induce activation of general defense responses ([Boller, 1995][1]).
Zipfel, Cyril, Robatzek, Silke
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Chromatin-Associated Molecular Patterns (CAMPs) in sepsis
Several molecular patterns have been identified that recognize pattern recognition receptors. Pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) are commonly used terminologies to classify molecules ...
Colleen P. Nofi, Ping Wang, Monowar Aziz
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Pathogenic Stress Induces Human Monocyte to Express an Extracellular Web of Tunneling Nanotubes
Actin-based tunneling nanotubes are a means of intercellular communication between remote cells. In the last decade, this type of nanotube was described in a wide variety of cell types and it became widely accepted that communication through these ...
Michal Shahar, Auryan Szalat, Haim Rosen
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Peripheral Neural Detection of Danger–Associated and Pathogen–Associated Molecular Patterns [PDF]
Bidirectional links between the nervous and immune systems modulate inflammation. The cellular mechanisms underlying the detection of danger-associated molecular patterns and pathogen-associated molecular patterns by the nervous system are not well understood.
Ackland, GL +4 more
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