Results 31 to 40 of about 206,862 (237)
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
Nature Communications, 2019 The authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern.
Arnab Pradhan +11 more
doaj +1 more source
Activation and regulation mechanisms of NOD-like receptors based on structural biology
Frontiers in Immunology, 2022 Innate immunity is a primary defense system against microbial infections. Innate immune pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens.
Umeharu Ohto
doaj +1 more source
CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns [PDF]
Trends in Immunology, 2009 It is now well accepted that the innate immune system recognizes both damage (or danger)- and pathogen-associated molecular patterns (DAMP and PAMP, respectively) through pattern recognition receptors, such as Toll-like receptors (TLR) and/or Nod-like receptors (NLR).
Yang, Liu, Guo-Yun, Chen, Pan, Zheng
openaire +2 more sources
Pathogen Associated Molecular Patterns, Pattern Recognition Receptors and Pediatric Sepsis [PDF]
The Open Inflammation Journal, 2011 The mortality of septic shock in the pediatric population has improved over the last 2 decades with better supportive care however it still remains unacceptably high. Exaggerated inflammatory responses early in septic shock have been associated with poor outcomes.
openaire +1 more source
Frontiers in Immunology, 2021 Both plants and animals are endowed with sophisticated innate immune systems to combat microbial attack. In these multicellular eukaryotes, innate immunity implies the presence of cell surface receptors and intracellular receptors able to detect danger ...
Thibault Roudaire +7 more
doaj +1 more source
γδ T Cells Respond Directly to Pathogen-Associated Molecular Patterns, [PDF]
The Journal of Immunology, 2005 Abstract γδ T cells recognize unprocessed or non-peptide Ags, respond rapidly to infection, and localize to mucosal surfaces. We have hypothesized that the innate functions of γδ T cells may be more similar to those of cells of the myeloid lineage than to other T cells.
Jodi F Hedges +2 more
openaire +1 more source
DAMPs and Innate Immune Training
Frontiers in Immunology, 2021 The ability to remember a previous encounter with pathogens was long thought to be a key feature of the adaptive immune system enabling the host to mount a faster, more specific and more effective immune response upon the reencounter, reducing the ...
Elisa Jentho +3 more
doaj +1 more source
NLRP3: Role in ischemia/reperfusion injuries
Frontiers in Immunology, 2022 NLR family pyrin domain containing 3 (NLRP3) is expressed in immune cells, especially in dendritic cells and macrophages and acts as a constituent of the inflammasome.
Soudeh Ghafouri-Fard +10 more
doaj +1 more source
Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants [PDF]
Journal of Visualized Experiments, 2009 To perceive potential pathogens in their environment, plants use pattern recognition receptors (PRRs) present on their plasma membranes. PRRs recognize conserved microbial features called pathogen-associated molecular patterns (PAMPs) and this detection leads to PAMP-triggered immunity (PTI), which effectively prevents colonization of plant tissues by ...
Chakravarthy, Suma +2 more
openaire +2 more sources
Innate immunity to malaria: The good, the bad and the unknown
Frontiers in Immunology, 2022 Malaria is the cause of 600.000 deaths annually. However, these deaths represent only a tiny fraction of total malaria cases. Repeated natural infections with the causative agent, Plasmodium sp.
Kai Pohl, Kai Pohl, Ian A. Cockburn
doaj +1 more source