Results 121 to 130 of about 256,778 (292)

Genomic relatedness within five common Finnish Campylobacter jejuni pulsed-field gel electrophoresis genotypes studied by amplified fragment length polymorphism analysis, ribotyping and serotyping

, 2001
Thirty-five Finnish Campylobacter jejuni strains with five SmaI/SacII pulsed-field gel electrophoresis (PFGE) genotypes selected among human and chicken isolates from 1997 and 1998 were used for comparison of their PFGE patterns, amplified fragment ...
Hanninen, M.L., Wagenaar, J.A., Rautelin, H., Perko Makela, P., Duim, B.   +4 more
core   +1 more source

Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica [PDF]

, 2013
Peer ...
Marco Mammella (421707), Julio C. Vega-Arreguin (421715), Horner, N. R., van Rooyen, D., Young, S. K., Guido van den Ackerveken (5650309), Stassen, J.H.M., Javier Dieguez-Uribeondo, Berg, H., Brett M. Tyler (19744), James Christie, Young, Sarah K, Grenville-Briggs, Laura J.,, Grenville-Briggs, L., Arnaud Bottin (41550), Elzbieta Rzeszutek (421711), Andrew J. Phillips (334915), Rooyen, D., van, van den Berg, H., Stan Oome (421709), Chad Nusbaum (253636), van den Berg, Herbert, Sarah K Young, Pieter van West (205267), Christie, James, Berend Snel, Rzeszutek, Elzbieta,, Lars Löbach, Horner, N.R., Díaz-Moreno, S.M., Sarah K. Young (178826), Morris, P., Seidl, M.F., de Bruijn, I., Joshua Z. Levin (177182), Levin, Joshua Z, Sucheta Tripathy, Meijer, Harold J. G., Grenville-Briggs, L. J., Secombes, Chris J, Secombes, Chris J., Grenville-Briggs, Laura J, Carsten Russ, Oome, Stan, Wawra, Stephan, Snel, Berend, Belmonte, Rodrigo, Mammella, M., Marcia Saraiva (421712), Elodie Gaulin (40047), Rodrigo Belmonte, Dieguez-Uribeondo, J., Marco Mammella, Sara M. Díaz-Moreno (421704), Qiandong Zeng (178764), Grenville-Briggs, L.J., Lin Fan (281949), Chad Nusbaum, Dumas, B., Levin, J.Z., Andrew J Phillips, Julio C Vega-Arreguin, Horner, Neil R, Sub Theoretical Biology & Bioinformatics, Haas, B., Dep Biologie, Tyler, Brett M., Meijer, H.J., van den Ackerveken, G., Löbach, Lars, Vega-Arreguin, Julio C, Russ, C., David van Rooyen, et al., Vega-Arreguin, Julio C., Bruijn, I., de, Govers, F., van West, Pieter, van den Ackerveken, A.F.J.M., Díaz-Moreno, S., Nusbaum, Chad, Chris J Secombes, Vega-Arreguin, J. C., Sub Plant-Microbe Interactions, Gaulin, Elodie, Sykes, Sean, Meijer, H.J.G., Irene de Bruijn, Seidl, Michael F., Wawra, S., Stassen, Joost H. M., Nusbaum, C., Paul Morris, Secombes, C.J., Stassen, Joost H M, Stephan Wawra, Laura J. Grenville-Briggs (421705), Bernard Dumas, Saraiva, M., Jiang, R., Phillips, Andrew J, Belmonte, R., Grenville-Briggs, Laura J., de Bruijn, Irene, Stan Oome, Haas, B. J., Harold J. G. Meijer (227595), Saraiva, Marcia, Qiandong Zeng, Rzeszutek, E., Stassen, J. H., Young, Sarah K., Young, S.K., Neil R Horner, Phillips, A. J., Joshua Z Levin, Jiang, R. H., Theoretical Biology and Bioinformatics, Stephan Wawra (421716), Joost H. M. Stassen (221771), David van Rooyen (421710), Bulone, Vincent, Irene de Bruijn (43879), van West, P., Sucheta Tripathy (19740), Secombes, C. J., Michael F. Seidl (221772), Snel, B., Levin, Joshua Z., Michael F Seidl, Gaulin, E., Bottin, A., Joost H M Stassen, Löbach, L., West, P., van, Bernard Dumas (40050), Díaz-Moreno, Sara M., Loebach, Lars, Guido van den Ackerveken, Lars Löbach (421702), Lin Fan, Haas, Brian J, Bulone, Vincent,, Herbert van den Berg, Jiang, Rays H. Y., Sean Sykes (158441), Vincent Bulone, Seidl, Michael F, Tripathy, S., Elzbieta Rzeszutek, Rzeszutek, Elzbieta, van Rooyen, David, Tyler, Brett M, Zeng, Qiandong, Levin, J. Z., Dieguez-Uribeondo, Javier, Morris, Paul, Díaz-Moreno, S. M., Govers, Francine, Tyler, B.M., Vincent Bulone (243055), Jiang, R.H.Y., Meijer, Harold J G, Marcia Saraiva, Neil R. Horner (421706), Arnaud Bottin, Meijer, H. J., Jiang, Rays H Y, Fan, Lin, Young, Sarah, Brett M Tyler, Bulone, V., Laura J Grenville-Briggs, Jiang, R.H.I., Elodie Gaulin, Horner, N., James Christie (421703), Tyler, B. M., Christie, J., Sean Sykes, de Haas, B.J., Sara M Díaz-Moreno, Francine Govers (52155), Francine Govers, Paul Morris (421708), van den Ackerveken, Guido, West, P., Oome, S., Berend Snel (5539), Zeng, Q., Haas, B.J., Chris J. Secombes (421713), Diaz-Moreno, Sara M.,, Vega-Arreguin, J.C., Javier Dieguez-Uribeondo (421717), Haas, Brian J., Fan, L., Carsten Russ (263594), Herbert van den Berg (421714), Sykes, S., Meijer, H., Stassen, J.H., Bottin, Arnaud, Horner, Neil R., Rays H Y Jiang, Ackerveken, G., van den, Russ, Carsten, Pieter van West, Levin, J., Rooyen, D., Plant Microbe Interactions, Harold J G Meijer, Rodrigo Belmonte (421701), Mammella, Marco, Phillips, Andrew J., Phillips, A.J., Brian J. Haas (81121), Rays H. Y. Jiang (421700), Seidl, M. F., Dumas, Bernard, Tripathy, Sucheta, Díaz-Moreno, Sara M, Brian J Haas   +222 more
core   +1 more source

Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood-brain barrier. [PDF]

Fluids Barriers CNS, 2023
Lye P, Bloise E, Matthews SG.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Roles of Innate Immune Cells in Atopic Dermatitis

Journal of Innate Immunity
Background: Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by recurrent eczematous lesions and severe pruritus. The economic burden and time penalty caused by the relapse of AD reduce patients’ life quality. Summary: AD has
Yuke Pan, Youyi Wang, Meinian Xu, Meizhen Zhong, Xiaoming Peng, Kang Zeng, Xiaowen Huang   +6 more
doaj   +1 more source

Innate Immune Recognition: An Issue More Complex Than Expected

Frontiers in Cellular and Infection Microbiology, 2019
Primary interaction of an intracellular bacterium with its host cell is initiated by activation of multiple signaling pathways in response to bacterium recognition itself or as cellular responses to stress induced by the bacterium.
Klara Kubelkova, Ales Macela
doaj   +1 more source

Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection

, 2008
Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Rostislav Skrabana, Michal Novak, Mangesh Bhide, Ivan Mikula Jr., Rastislav Mucha, Lucia Kisova, Ivan Mikula Sr.   +6 more
core  

Cancer vaccines from cryogenically silicified tumour cells functionalized with pathogen-associated molecular patterns. [PDF]

Nat Biomed Eng, 2022
Guo J, De May H, Franco S, Noureddine A, Tang L, Brinker CJ, Kusewitt DF, Adams SF, Serda RE.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source