Results 11 to 20 of about 861,453 (229)

Avian Pattern Recognition Receptor Sensing and Signaling [PDF]

Veterinary Sciences, 2020
Pattern recognition receptors (PRRs) are a class of immune sensors that play a critical role in detecting and responding to several conserved patterns of microorganisms.
Sabari Nath Neerukonda, Upendra Katneni
doaj   +3 more sources

Dynamin-Related Proteins Enhance Tomato Immunity by Mediating Pattern Recognition Receptor Trafficking [PDF]

Membranes, 2022
Pattern recognition receptor (PRR) trafficking to the plasma membrane and endocytosis plays a crucial role in pattern triggered immunity (PTI). Dynamin-related proteins (DRPs) participate in endocytosis and recycling.
Meirav Leibman-Markus, Silvia Schuster, Beatriz Vasquez-Soto, Maya Bar, Adi Avni, Lorena Pizarro   +5 more
doaj   +2 more sources

Inflammasome-Associated Gastric Tumorigenesis Is Independent of the NLRP3 Pattern Recognition Receptor [PDF]

Frontiers in Oncology, 2022
Inflammasomes are important multiprotein regulatory complexes of innate immunity and have recently emerged as playing divergent roles in numerous inflammation-associated cancers.
Alice J. West, Alice J. West, Virginie Deswaerte, Virginie Deswaerte, Alison C. West, Alison C. West, Linden J. Gearing, Linden J. Gearing, Patrick Tan, Patrick Tan, Patrick Tan, Brendan J. Jenkins, Brendan J. Jenkins   +12 more
doaj   +2 more sources

RIG-I: a multifunctional protein beyond a pattern recognition receptor

Protein & Cell, 2017
It was widely known that retinoic acid inducible gene I (RIG-I) functions as a cytosolic pattern recognition receptor that initiates innate antiviral immunity by detecting exogenous viral RNAs.
Xiao-xiao Xu, Han Wan, Li Nie, Tong Shao, Li-xin Xiang, Jian-zhong Shao   +5 more
doaj   +2 more sources

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]

Mediators of Inflammation, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj   +5 more sources

Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis

Protein & Cell, 2020
While emerging data suggest nucleotide oligomerization domain receptor 1 (NOD1), a cytoplasmic pattern recognition receptor, may play an important and complementary role in the immune response to bacterial infection, its role in cancer metastasis is ...
Henry Y. Jiang, Sara Najmeh, Guy Martel, Elyse MacFadden-Murphy, Raquel Farias, Paul Savage, Arielle Leone, Lucie Roussel, Jonathan Cools-Lartigue, Stephen Gowing, Julie Berube, Betty Giannias, France Bourdeau, Carlos H. F. Chan, Jonathan D. Spicer, Rebecca McClure, Morag Park, Simon Rousseau, Lorenzo E. Ferri   +18 more
doaj   +2 more sources

Transgenic expression of the dicotyledonous pattern recognition receptor EFR in rice leads to ligand-dependent activation of defense responses [PDF]

bioRxiv, 2015
Plant plasma membrane localized pattern recognition receptors (PRRs) detect extracellular pathogen-associated molecules. PRRs such as Arabidopsis EFR and rice XA21 are taxonomically restricted and are absent from most plant genomes.
A Afroz, A Daudi, A Heese, A Keller, AP Macho, AP Macho, Arsalan Daudi, B Schulze, B Schwessinger, B Schwessinger, Benjamin Schwessinger, BM Lee, BMJ Mendes, C Segonzac, C Zipfel, C-J Park, C-J Park, Christopher Daum, Christopher J. Petzold, CJ Park, CJ Park, CJ Park, CR Clarke, Cyril Zipfel, D Chinchilla, D Chinchilla, D Chinchilla, D Kim, D Lu, Deling Ruan, DJ McCarthy, E Fradin, F Lu, G Felix, G Kunze, G Qian, H Haweker, H Hirai, H Ochiai, H Schoonbeek, H Wickham, H Zhang, J Li, J Li, J Monaghan, J Zhang, JD Jones, JF González, JN Tripathi, Joshua L. Heazlewood, K Kishimoto, L Trdá, LA Boyd, M Albert, M Boudsocq, M Boudsocq, M Lopez-Gomez, M Roux, Mansi Chovatia, MD Robinson, MS Chern, N Holton, Nicolas Holton, Nicolas Thomas, O Bahar, Ofir Bahar, P Schulze-Lefert, Pamela C. Ronald, Patrick E. Canlas, PC Ronald, R Cai, R De Jonge, R Lozano-Durán, R Sharma, R Takai, Rita Kuo, S Lacombe, S Tan, S Wang, S Zuo, SH Spoel, SL Salzberg, ST Chisholm, SW Lee, T Boller, T Furukawa, T Maekawa, T Nakagawa, T Xiang, V Nekrasov, Vasanth R. Singan, Vladimir Nekrasov, W Liu, Wenbo Ma, WY Song, WY Song, X Chen, X Chen, X Chen, X Chen, Y Ao, Y Hiei, Y Jiang, Y Kadota, Y Katsuragi, Y Kawahara, Y Kawano, Y Peng, Y Saijo, Y Saijo, Y Xiang, YS Seo, YS Wang   +112 more
core   +13 more sources

DM9 Domain Containing Protein Functions As a Pattern Recognition Receptor with Broad Microbial Recognition Spectrum

Frontiers in Immunology, 2017
DM9 domain was first identified in Drosophila melanogaster, and it was subsequently found to integrate with or without other protein domains across a wide range of invertebrates and vertebrates.
Shuai Jiang, Lingling Wang, Mengmeng Huang, Zhihao Jia, Tobias Weinert, Eberhard Warkentin, Conghui Liu, Xiaorui Song, Haixia Zhang, Jennifer Witt, Limei Qiu, Guohong Peng, Guohong Peng, Linsheng Song   +13 more
doaj   +2 more sources

Cnidarian Pattern Recognition Receptor Repertoires Reflect Both Phylogeny and Life History Traits [PDF]

Frontiers in Immunology, 2021
Pattern recognition receptors (PRRs) are evolutionarily ancient and crucial components of innate immunity, recognizing danger-associated molecular patterns (DAMPs) and activating host defenses.
Madison A. Emery, Bradford A. Dimos, Laura D. Mydlarz   +2 more
doaj   +2 more sources

NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages. [PDF]

Sci Immunol, 2023
Endotoxin - bacterial lipopolysaccharide (LPS) - is a driver of the lethal infection sepsis through activation of innate immune responses. When delivered to the cytosol of macrophages, LPS (cLPS) induces the assembly of an inflammasome that contains ...
Rojas-Lopez M, Gil-Marqués ML, Kharbanda V, Zajac AS, Miller KA, Wood TE, Hachey AC, Egger KT, Goldberg MB.   +8 more
europepmc   +2 more sources