Results 11 to 20 of about 4,628,126 (296)
Pattern recognition receptor signaling in otitis media: immune crosstalk and pathogenic mechanisms [PDF]
Frontiers in ImmunologyOtitis media (OM) remains a prevalent and multifactorial inflammatory disease of the middle ear, especially in pediatric populations. The immune system, particularly pattern recognition receptors (PRRs), plays a central role in detecting microbial ...
Mingwen Guo +5 more
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Frontiers in Immunology, 2017 DM9 domain was first identified in Drosophila melanogaster, and it was subsequently found to integrate with or without other protein domains across a wide range of invertebrates and vertebrates.
Shuai Jiang +13 more
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Cnidarian Pattern Recognition Receptor Repertoires Reflect Both Phylogeny and Life History Traits
Frontiers in Immunology, 2021 Pattern recognition receptors (PRRs) are evolutionarily ancient and crucial components of innate immunity, recognizing danger-associated molecular patterns (DAMPs) and activating host defenses.
Madison A. Emery +2 more
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Role of pattern recognition and search in expert decision making [PDF]
, 2004 Recently, proponents of the predominant role of search processes have collected data aiming at undermining the importance of pattern recognition. In particular, Chabris and Hearst (2003), using data from rapid chess and blindfold chess, have questioned ...
Gobet, F
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Inhibitory pattern recognition receptors
Journal of Experimental Medicine, 2021 Pathogen- and damage-associated molecular patterns are sensed by the immune system’s pattern recognition receptors (PRRs) upon contact with a microbe or damaged tissue. In situations such as contact with commensals or during physiological cell death, the immune system should not respond to these patterns.
Matevž Rumpret +3 more
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Pattern Recognition Receptors and Autophagy [PDF]
Frontiers in Immunology, 2014 The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control immune responses.
Oh, JE Oh, Ji Eun +1 more
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Identifying the Patterns of Pattern Recognition Receptors [PDF]
Immunity, 2018 Intestinal homeostasis requires microbial recognition that results in appropriate responses to commensals and pathogens. In this issue of Immunity, Price et al. (2018) map the in vivo expression of five toll-like receptors (TLR) in intestinal epithelia, revealing distinct spatio-temporal expression patterns that shape responses to TLR ligands.
Andrea A, Hill, Gretchen E, Diehl
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Pattern Recognition Receptors and Inflammation [PDF]
Cell, 2010 Infection of cells by microorganisms activates the inflammatory response. The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors.
Takeuchi, Osamu, Akira, Shizuo
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Japanese Journal of Clinical Immunology, 2011 Immunity is based on self/nonself discrimination. In vertebrates, two major systems, innate and adaptive immune systems, constitute host defense against invading microbes. Adaptive immunity is characterized by specific immune responses through B- or T-cell antigen receptors that are generated by somatic recombination, whereas nonspecific responses to ...
Takaya, Hayashi +2 more
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Nature Communications, 2022 Pattern-triggered immunity is activated by recognition of microbe-derived structures by host pattern recognition receptors. Here the authors use a genotype-by sequencing approach to show that bacterial translation initiation factor 1 triggers PTI in ...
Li Fan +15 more
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