Anticancer properties of peptide fragments of hair proteins. [PDF]
PLoS ONE, 2014 The primary function of hair and fur covering mammalian skin is to provide mechanical and thermal protection for the body. The proteins that constitute hair are extremely resistant to degradation by environmental factors.
Sergiusz Markowicz +9 more
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Comparative studies for amyloid beta degradation: “Neprilysin vs insulysin”, “monomeric vs aggregate”, and “whole Aβ40 vs its peptide fragments” [PDF]
Biochemistry and Biophysics Reports, 2022 Amyloid beta (Aβ) proteins are produced from amyloid precursor protein cleaved by β- and γ-secretases, and are the main components of senile plaques pathologically found in Alzheimer's disease (AD) patient brains.
Dai Kato +5 more
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Greener Cleavage of Protected Peptide Fragments from Sieber Amide Resin [PDF]
ChemistryOpen, 2022 Following the successful introduction of two benign solvents for cleaving protected acid peptide fragments from 2‐chlorotrityl chloride (2‐CTC) resin, there is a need to green the cleavage process for obtaining protected peptide amide fragments.
Dr. Othman Al Musaimi +2 more
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Effects of Aβ-derived peptide fragments on fibrillogenesis of Aβ [PDF]
Scientific Reports, 2021 Amyloid β (Aβ) peptide aggregation plays a central role in Alzheimer’s disease (AD) etiology. AD drug candidates have included small molecules or peptides directed towards inhibition of Aβ fibrillogenesis.
Faisal Abedin +2 more
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Tracking the Amide I and αCOO− Terminal ν(C=O) Raman Bands in a Family of l-Glutamic Acid-Containing Peptide Fragments: A Raman and DFT Study [PDF]
Molecules, 2021 The E-hook of β-tubulin plays instrumental roles in cytoskeletal regulation and function. The last six C-terminal residues of the βII isotype, a peptide of amino acid sequence EGEDEA, extend from the microtubule surface and have eluded characterization ...
Ashley E. Williams +3 more
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A Model of Demasking and Hydrolysis of Peptide Bonds During Tryptic Digestion of β-Casein and β-Lactoglobulin [PDF]
MoleculesThe prediction of polypeptide chain fragmentation during digestion (proteolysis) of protein substrates by trypsin was carried out for globular β-lactoglobulin (β-LG) and micellar β-casein (β-CN).
Mikhail M. Vorob’ev
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Protein-Peptide Complex Prediction through Fragment Interaction Patterns [PDF]
Structure, 2013 The number of protein-peptide interactions in a cell is so large that experimental determination of all these complex structures would be a daunting task. Although homology modeling and refinement protocols have vastly improved the number and quality of predicted structural models, ab initio methods are still challenged by both the large number of ...
Erik Verschueren +4 more
openalex +5 more sources
SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting. [PDF]
Proc Natl Acad Sci U S AZhang Y +34 more
europepmc +2 more sources
Copper(II), Nickel(II) and Zinc(II) Complexes of Peptide Fragments of Tau Protein. [PDF]
MoleculesKastal Z +6 more
europepmc +3 more sources
Antimicrobial Peptide Designing and Optimization Employing Large-Scale Flexibility Analysis of Protein-Peptide Fragments [PDF]
ACS Omega, 2019 Neeraj Kumar +3 more
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