Self-Assembly of Lipopeptides Containing Short Peptide Fragments Derived from the Gastrointestinal Hormone PYY3-36: From Micelles to Amyloid Fibrils. [PDF]
J Phys Chem B, 2019 We investigate the impact of lipidation on the self-assembly of two peptide fragments from the gastrointestinal peptide hormone PYY3–36. The lipopeptides C16IKPEAP and C16IKPEAPGE contain the first 6 and 8 amino acid residues, respectively, from the PYY3–
Hutchinson JA +5 more
europepmc +2 more sources
Coordination Environment of Cu(II) Ions Bound to N-Terminal Peptide Fragments of Angiogenin Protein. [PDF]
Int J Mol Sci, 2016 Angiogenin (Ang) is a potent angiogenic factor, strongly overexpressed in patients affected by different types of cancers. The specific Ang cellular receptors have not been identified, but it is known that Ang–actin interaction induces changes both in ...
Magrì A +8 more
europepmc +2 more sources
Epimerization-Free C-Term Activation of Peptide Fragments by Ball Milling.
Organic Letters, 2020 Peptides were produced in high yields and, if any, very low epimerization, by mechanochemical coupling of peptide fragments containing highly epimerization-prone and/or highly hindered amino acids at C-term. Ball milling was clearly identified as the key
Yves Yeboue +5 more
semanticscholar +1 more source
Light-Induced Orthogonal Fragmentation of Crosslinked Peptides [PDF]
JACS Au, 2023 Crosslinking mass spectrometry provides pivotal information on the structure and interaction of proteins. MS-cleavable crosslinkers are regarded as a cornerstone for the analysis of complex mixtures. Yet they fragment under similar conditions as peptides, leading to mixed fragmentation spectra of the crosslinker and peptide.
Lars Kolbowski +4 more
openaire +4 more sources
Biomolecules, 2020 Lynx1, membrane-bound protein co-localized with the nicotinic acetylcholine receptors (nAChRs) and regulates their function, is a three-finger protein (TFP) made of three β-structural loops, similarly to snake venom α-neurotoxin TFPs.
Konstantin S. Mineev +11 more
doaj +1 more source
Foods, 2023 In this study, we investigated the transport mechanism of immune-active peptide fragments isolated from casein gastrointestinal hydrolysates via a Caco-2 monolayer.
Haiyan Xue +7 more
doaj +1 more source
Plants, 2020 We report the inhibitory effect of peptide extracts obtained from seven medicinal plants against a causative agent of late blight disease Phytophthora infestans.
Eugene A. Rogozhin +5 more
doaj +1 more source
Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. [PDF]
PLoS ONE, 2013 Highly pathogenic avian influenza (HPAI) H5N1 viruses, which have emerged in poultry and other wildlife worldwide, contain a characteristic multi-basic cleavage site (CS) in the hemagglutinin protein (HA).
Jinhua Dong +5 more
doaj +1 more source
The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release. [PDF]
PLoS ONE, 2018 Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4+ T cells as part of the immune system's surveillance of pathogens and malignancy.
Maria Pia Negroni, Lawrence J Stern
doaj +1 more source
Highly amyloidogenic two-chain peptide fragments are released upon partial digestion of insulin with pepsin. [PDF]
J Biol Chem, 2015 Background: Insulin is a model amyloidogenic protein. Results: Limited proteolysis of bovine insulin dimers with pepsin releases highly fibrillation-prone two-chain fragments.
Piejko M +6 more
europepmc +2 more sources