Results 11 to 20 of about 2,005,992 (360)

Fragmentation of amidinated peptide ions [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2004
The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be ...
Richard L. Beardsley, James P. Reilly
openaire   +3 more sources

The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human Sepsis. [PDF]

open access: yesPLoS ONE, 2015
Heparanase is an endo-β-glucuronidase that cleaves heparan sulfate side chains from their proteoglycans. Thereby, heparanase liberates highly potent circulating heparan sulfate-fragments (HS-fragments) and triggers the fatal and excessive inflammatory ...
Lukas Martin   +8 more
doaj   +1 more source

Hit-to-Lead Short Peptides against Dengue Type 2 Envelope Protein: Computational and Experimental Investigations

open access: yesMolecules, 2022
Data from the World Health Organisation show that the global incidence of dengue infection has risen drastically, with an estimated 400 million cases of dengue infection occurring annually.
Norburhanuddin Johari Zaidi   +5 more
doaj   +1 more source

Signature Fragment Ions of Biotinylated Peptides [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2020
The use of biotin or biotin-containing reagents is an essential component of many protein purification and labeling technologies. Owing to its small size and high affinity to the avidin family of proteins, biotin is a versatile molecular handle that permits both enrichment and purity that is not easily achieved by other reagents. Traditionally, the use
Dae In Kim   +16 more
openaire   +4 more sources

Epimerization-Free C-Term Activation of Peptide Fragments by Ball Milling.

open access: yesOrganic Letters, 2020
Peptides were produced in high yields and, if any, very low epimerization, by mechanochemical coupling of peptide fragments containing highly epimerization-prone and/or highly hindered amino acids at C-term. Ball milling was clearly identified as the key
Yves Yeboue   +5 more
semanticscholar   +1 more source

Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

open access: yesBiomolecules, 2020
Lynx1, membrane-bound protein co-localized with the nicotinic acetylcholine receptors (nAChRs) and regulates their function, is a three-finger protein (TFP) made of three β-structural loops, similarly to snake venom α-neurotoxin TFPs.
Konstantin S. Mineev   +11 more
doaj   +1 more source

Identification of Immune-Active Peptides in Casein Hydrolysates and Its Transport Mechanism on a Caco-2 Monolayer

open access: yesFoods, 2023
In this study, we investigated the transport mechanism of immune-active peptide fragments isolated from casein gastrointestinal hydrolysates via a Caco-2 monolayer.
Haiyan Xue   +7 more
doaj   +1 more source

Light-Induced Orthogonal Fragmentation of Crosslinked Peptides [PDF]

open access: yesJACS Au, 2023
Crosslinking mass spectrometry provides pivotal information on the structure and interaction of proteins. MS-cleavable crosslinkers are regarded as a cornerstone for the analysis of complex mixtures. Yet they fragment under similar conditions as peptides, leading to mixed fragmentation spectra of the crosslinker and peptide.
Lars Kolbowski   +4 more
openaire   +3 more sources

Peptide Extracts from Seven Medicinal Plants Discovered to Inhibit Oomycete Phytophthora infestans, a Causative Agent of Potato Late Blight Disease

open access: yesPlants, 2020
We report the inhibitory effect of peptide extracts obtained from seven medicinal plants against a causative agent of late blight disease Phytophthora infestans.
Eugene A. Rogozhin   +5 more
doaj   +1 more source

Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. [PDF]

open access: yesPLoS ONE, 2013
Highly pathogenic avian influenza (HPAI) H5N1 viruses, which have emerged in poultry and other wildlife worldwide, contain a characteristic multi-basic cleavage site (CS) in the hemagglutinin protein (HA).
Jinhua Dong   +5 more
doaj   +1 more source

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