Results 31 to 40 of about 2,313,645 (331)

Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]

open access: yes, 1982
Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J.   +3 more
core   +2 more sources

The data of heterologous expression protocol for synthesis of 15N, 13C-labeled SEM1(68-107) peptide fragment of homo sapiens semenogelin 1

open access: yesMethodsX, 2021
The semenogelin 1 protein is secreted in the seminal vesicles. After ejaculation it is split into small peptide fragments using internal proteases.
Aydar Bikmullin   +3 more
doaj   +1 more source

Leveraging the multivalent p53 peptide-MdmX interaction to guide the improvement of small molecule inhibitors

open access: yesNature Communications, 2022
Peptide fragments derived from the interfaces of protein-protein interactions (PPIs) provide useful templates for designing small molecule PPI inhibitors.
Xiyao Cheng   +8 more
doaj   +1 more source

Probing the mechanism of electron capture and electron transfer dissociation using tags with variable electron affinity [PDF]

open access: yes, 2009
Electron capture dissociation (ECD) and electron transfer dissociation (ETD) of doubly protonated electron affinity (EA)-tuned peptides were studied to further illuminate the mechanism of these processes. The model peptide FQpSEEQQQTEDELQDK, containing a
Beauchamp, J. L.   +5 more
core   +2 more sources

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis [PDF]

open access: yes, 2009
Antibodies to citrulline-modifi ed proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear.
Aho   +69 more
core   +2 more sources

Functional Divergence of Glycoprotein Hormone Receptors [PDF]

open access: yes, 2010
Two lamprey glycroprotein hormone receptors (lGpH-R I and II) highly similar with gnathostome GpH-Rs were cloned from sea lamprey testes and thyroid, respectively.
Freamat, Mihael, Sower, Stacia A.
core   +3 more sources

High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock

open access: yesbioRxiv, 2017
Peptide-protein interactions contribute a significant fraction of the protein-protein interactome. Accurate modeling of these interactions is challenging due to the vast conformational space associated with interactions of highly flexible peptides with ...
Nawsad Alam   +5 more
semanticscholar   +1 more source

Absolute Protein Amounts and Relative Abundance of Volume-regulated Anion Channel (VRAC) LRRC8 Subunits in Cells and Tissues Revealed by Quantitative Immunoblotting [PDF]

open access: yes, 2019
The volume-regulated anion channel (VRAC) plays an important role in osmotic cell volume regulation. In addition, it is involved in various physiological processes such as insulin secretion, glia-neuron communication and purinergic signaling.
Kopp, Anja   +3 more
core   +1 more source

Temperature-sensitive protein–DNA dimerizers [PDF]

open access: yes, 2005
Programmable DNA-binding polyamides coupled to short peptides have led to the creation of synthetic artificial transcription factors. A hairpin polyamide-YPWM tetrapeptide conjugate facilitates the binding of a natural transcription factor Exd to an ...
Ansari, Aseem Z.   +6 more
core   +1 more source

Atypical signaling and functional desensitization response of MAS receptor to peptide ligands. [PDF]

open access: yesPLoS ONE, 2014
MAS is a G protein-coupled receptor (GPCR) implicated in multiple physiological processes. Several physiological peptide ligands such as angiotensin-(1-7), angiotensin fragments and neuropeptide FF (NPFF) are reported to act on MAS.
Kalyan C Tirupula   +3 more
doaj   +1 more source

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