Results 1 to 10 of about 855,791 (338)
Total wash elimination for solid phase peptide synthesis [PDF]
Nature Communications, 2023 We present a process for solid phase peptide synthesis (SPPS) that completely eliminates all solvent intensive washing steps during each amino acid addition cycle.
Jonathan M. Collins +6 more
doaj +2 more sources
Epimerisation in Peptide Synthesis. [PDF]
Molecules, 2023 Epimerisation is basically a chemical conversion that includes the transformation of an epimer into another epimer or its chiral partner. Epimerisation of amino acid is a side reaction that sometimes happens during peptide synthesis. It became the most avoided reaction because the process affects the overall conformation of the molecule, eventually ...
Duengo S +4 more
europepmc +4 more sources
Acid-Modulated Peptide Synthesis for Application on Oxide Biosensor Interfaces [PDF]
Nanomaterials, 2023 In this paper we report an acid-modulated strategy for novel peptide microarray production on biosensor interfaces. We initially selected a controlled pore glass (CPG) as a support for solid-phase peptide synthesis (SPPS) to implement a chemistry that ...
Edgar Cristóbal-Lecina +7 more
doaj +2 more sources
Bio-Protocol, 2012 This protocol describes the synthesis of peptides for affinity testing and bioconjugate with solid phase peptide synthesizer at a small scale.
zheng miao, Zhen Cheng
doaj +2 more sources
Frontiers in Chemistry, 2023 Modern medicine has developed a myriad of therapeutic drugs against a wide range of human diseases leading to increased life expectancy and better quality of life for millions of people.
Ray Yurko +4 more
doaj +1 more source
Antibiotics, 2022 Antimicrobial peptides (AMPs) are considered to be a valuable source for the identification and/or design of promising candidates for the development of antifungal treatments, since they have advantages such as lower tendency to induce resistance, ease ...
Katherine Aguirre-Guataqui +7 more
doaj +1 more source
Introduction to Peptide Synthesis [PDF]
Current Protocols in Protein Science, 2001 AbstractA number of synthetic peptides are significant commercial or pharmaceutical products, ranging from the dipeptide sugar‐substitute aspartame to clinically used hormones, such as oxytocin, adrenocorticotropic hormone, and calcitonin. This unit provides an overview of the field of synthetic peptides and proteins, including their purification.
Maciej, Stawikowski, Gregg B, Fields
openaire +8 more sources
Scientific Reports, 2022 This manuscript reports an impressive and facile strategy for synthesizing isoxazole derivatives using immobilized Cu (I) in metformin-functionalized β-cyclodextrin as a catalyst.
Mahdieh Tajbakhsh +3 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 The first heterologous expression of genes responsible for the production of rhamnolipids was already implemented in the mid-1990s during the functional identification of the rhlAB operon.
Andreas Wittgens +4 more
doaj +1 more source
Marine Drugs, 2023 Conotoxins are a class of disulfide-rich peptides found in the venom of cone snails, which have attracted considerable attention in recent years due to their potent activity on ion channels and potential for therapeutics.
Yong Wu +6 more
doaj +1 more source