Results 11 to 20 of about 855,791 (338)
Synthesis, Characterization and Evaluation of Peptide Nanostructures for Biomedical Applications
Molecules, 2021 There is a challenging need for the development of new alternative nanostructures that can allow the coupling and/or encapsulation of therapeutic/diagnostic molecules while reducing their toxicity and improving their circulation and in-vivo targeting ...
Fanny d’Orlyé +5 more
doaj +1 more source
Molecules, 2023 The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone +7 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways.
Isabel Bator +8 more
doaj +1 more source
Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies
Marine Drugs, 2022 Oceans are a rich source of structurally unique bioactive compounds from the perspective of potential therapeutic agents. Marine peptides are a particularly interesting group of secondary metabolites because of their chemistry and wide range of ...
Ricardo Ribeiro +3 more
doaj +1 more source
Molecules, 2021 Our formerly described pentapeptide opioid analog Tyr-c[D-Lys-Phe-Phe-Asp]NH2 (designated RP-170), showing high affinity for the mu (MOR) and kappa (KOR) opioid receptors, was much more stable than endomorphine-2 (EM-2) in the rat brain homogenate and ...
Karol Wtorek +6 more
doaj +1 more source
Foods, 2022 A soy protein isolate was hydrolyzed with Alcalase®, Flavourzyme® and their combination, and the resulting hydrolysates (A, F and A + F) were ultrafiltered and analyzed through SDS-PAGE.
Sara Sangiorgio +11 more
doaj +1 more source
Development of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell Characterisation [PDF]
, 2012 Incorporation of cleavable linkers into peptides and proteins is of particular value in the study of biological processes. Here we describe the synthesis of a cleavable linker that is hypersensitive to oxidative cleavage as the result of the periodate ...
Altman +28 more
core +1 more source
Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues [PDF]
, 1994 We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique.
Dagnino, L. +3 more
core +5 more sources
Real-time monitoring of solid-phase peptide synthesis using a variable bed flow reactor [PDF]
, 2019 On-resin aggregation and incomplete amide bond formation are major challenges for solid-phase peptide synthesis that are difficult to be monitored in real-time.
Guthrie, Duncan +3 more
core +2 more sources
An orthogonally protected CycloTriVeratrylene (CTV) as a highly pre-organized molecular scaffold for subsequent ligation of different cyclic peptides towards protein mimics [PDF]
, 2017 The synthesis of a semi-orthogonally protected CycloTriVeratrilene (CTV) scaffold derivative as well as the sequential introduction of three different peptide loops onto this molecular scaffold via Cu(I)-catalyzed azide alkyne cycloaddition towards a ...
Liskamp, Rob M.J. +2 more
core +1 more source