Results 11 to 20 of about 4,400,665 (341)
Aza-peptides: expectations and reality [PDF]
Proceedings of the Estonian Academy of Sciences, 2022 The replacement of the α-carbon atom in an α-amino acid structure by a nitrogen atom yields alkylcarbazic acids, also known as α-aza amino acids.
Anu Ploom +4 more
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Epimerisation in Peptide Synthesis
Molecules, 2023 Epimerisation is basically a chemical conversion that includes the transformation of an epimer into another epimer or its chiral partner. Epimerisation of amino acid is a side reaction that sometimes happens during peptide synthesis. It became the most avoided reaction because the process affects the overall conformation of the molecule, eventually ...
Suleman Duengo +4 more
openaire +3 more sources
Synthesis, Characterization and Evaluation of Peptide Nanostructures for Biomedical Applications
Molecules, 2021 There is a challenging need for the development of new alternative nanostructures that can allow the coupling and/or encapsulation of therapeutic/diagnostic molecules while reducing their toxicity and improving their circulation and in-vivo targeting ...
Fanny d’Orlyé +5 more
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Molecules, 2023 The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone +7 more
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Molecules, 2021 Our formerly described pentapeptide opioid analog Tyr-c[D-Lys-Phe-Phe-Asp]NH2 (designated RP-170), showing high affinity for the mu (MOR) and kappa (KOR) opioid receptors, was much more stable than endomorphine-2 (EM-2) in the rat brain homogenate and ...
Karol Wtorek +6 more
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Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies
Marine Drugs, 2022 Oceans are a rich source of structurally unique bioactive compounds from the perspective of potential therapeutic agents. Marine peptides are a particularly interesting group of secondary metabolites because of their chemistry and wide range of ...
Ricardo Ribeiro +3 more
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Nature Communications, 2020 Although peptide chemistry has made great progress, the frequent occurrence of aspartimide formation during peptide synthesis remains a formidable challenge.
K. Neumann +3 more
semanticscholar +1 more source
Foods, 2022 A soy protein isolate was hydrolyzed with Alcalase®, Flavourzyme® and their combination, and the resulting hydrolysates (A, F and A + F) were ultrafiltered and analyzed through SDS-PAGE.
Sara Sangiorgio +11 more
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Frontiers in Bioengineering and Biotechnology, 2020 Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways.
Isabel Bator +8 more
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Marine Drugs, 2023 Conotoxins are a class of disulfide-rich peptides found in the venom of cone snails, which have attracted considerable attention in recent years due to their potent activity on ion channels and potential for therapeutics.
Yong Wu +6 more
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