Results 51 to 60 of about 34,630 (291)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Leadership, Perceived Organisational Support and Employee Wellbeing Experimental Study

, 2021
The project is interested in experimentally investigating the link between leadership style and employee wellbeing through perceived organisational ...
Ana C. Leite, Georgina Randsley de Moura, Christie Jade Marsh   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Care coordinators' responses to clients' trauma: the role of coping and perceived organisational support [PDF]

, 2013
Research suggests that working with trauma survivors can result in a range of negative effects including ‘vicarious trauma’, ‘secondary trauma’, ‘compassion fatigue’ and ‘burnout’ amongst other things.
Radford, R.
core  

When rendering hospitality becomes collateral damage: Psycho-organisational variables and job burnout amongst hotel workers in metropolitan Nigeria

SA Journal of Industrial Psychology, 2013
Orientation: Job burnout is a serious problem in the hospitality industry. Therefore, employees require ongoing job and personal resources to cope with job burnout. Research purpose: The study investigated the influence of psycho-organisational variables
Oluyinka Ojedokun, Erhabor S. Idemudia, Arike O. Omotoso   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Ethical behaviour, organisational support and employee outcomes in driving public sector organisational performance [PDF]

RAUSP Management Journal
PurposeThis study aims to investigate the relationships between ethical behaviour, perceived organisational support (POS) and organisational performance within Nigeria’s Federal Ministry of Labour and Employment (FMLE).Design/methodology/approachThis ...
Abdulrazaq Kayode Abdulkareem, Abdulrasaq Ajadi Ishola, Zulfah Jumoke Abdulkareem, Kazeem Adebayo Oladimeji, Abdulhakeem Adejumo, Ahmad Ajibola Ayinla   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

From Organisation’s Affective Commitment to Employees’ Extra Role Behaviour: A Sequential Effect

Journal of Work and Organizational Psychology
The aim of this study is to examine the association between organisation’s affective commitment and employees’ organisational citizenship behaviour.
Joaquín García-Cruz, Ramón Valle-Cabrera   +1 more
doaj   +1 more source

Relationship between perceived organizational support, leadership behavior, and job satisfaction: An empirical study in Iran

Intangible Capital, 2010
As the second largest producer of cement after Egypt in the Middle East, Iran planned to increase production from 33 million ton/yr (Mt/yr) currently to 70 Mt/yr by 2021 due to increase in local demand and also to compete in export markets (Dehqan, 2002).
Zainal Ariffin Ahmad, Zeinab Amini Yekta
doaj   +1 more source