Results 51 to 60 of about 148,079 (169)

Simulating optical coherence tomography for observing nerve activity: a finite difference time domain bi-dimensional model [PDF]

open access: yesPLOS ONE 2018, 13, 1-14, 2017
We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference signal in post processing, it is possible to reduce the computational time required by the simulations and, thus, to ...
arxiv   +1 more source

Extracting morphometric information from rat sciatic nerve using optical coherence tomography [PDF]

open access: yesHope, J., Braeuer, B., Amirapu, S., McDaid, A., & Vanholsbeeck, F. (2018). Extracting morphometric information from rat sciatic nerve using optical coherence tomography. Journal of biomedical optics, 23 (11), 1-14, 2018
We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological measurements accurate to +/-1 um. The three OCT techniques are: 1) average depth resolved profile (ADRP); 2) autoregressive
arxiv   +1 more source

The balanced microenvironment regulated by the degradants of appropriate PLGA scaffolds and chitosan conduit promotes peripheral nerve regeneration

open access: yesMaterials Today Bio, 2021
Tissue-engineered nerve grafts (TENGs) are the most promising way for repairing long-distance peripheral nerve defects. Chitosan and poly (lactic-co-glycolic acid) (PLGA) scaffolds are considered as the promising materials in the pharmaceutical and ...
Panjian Lu   +8 more
doaj  

The influence of BACE1 on macrophage recruitment and activity in the injured peripheral nerve

open access: yesJournal of Neuroinflammation, 2021
Following peripheral nerve injury, multiple cell types, including axons, Schwann cells, and macrophages, coordinate to promote nerve regeneration. However, this capacity for repair is limited, particularly in older populations, and current treatments are
John A. Fissel, Mohamed H. Farah
doaj   +1 more source

Repair and regeneration of peripheral nerve injuries that ablate branch points

open access: yesNeural Regeneration Research, 2023
The peripheral nervous system has an extensive branching organization, and peripheral nerve injuries that ablate branch points present a complex challenge for clinical repair.
JuliAnne E Allgood   +2 more
doaj   +1 more source

Peripheral nerve regeneration and intraneural revascularization

open access: yesNeural Regeneration Research, 2019
Peripheral nerves are particularly vulnerable to injuries and are involved in numerous pathologies for which specific treatments are lacking. This review summarizes the pathophysiological features of the most common traumatic nerve injury in humans and ...
Martial Caillaud   +4 more
semanticscholar   +1 more source

Roles of SMAD and SMAD-Associated Signaling Pathways in Nerve Regeneration Following Peripheral Nerve Injury: A Narrative Literature Review

open access: yesCurrent Issues in Molecular Biology
Although several methods are being applied to treat peripheral nerve injury, a perfect treatment that leads to full functional recovery has not yet been developed. SMAD (Suppressor of Mothers Against Decapentaplegic Homolog) plays a crucial role in nerve
Jeongmin Lee   +7 more
doaj   +1 more source

Advances in 3D printing scaffolds for peripheral nerve and spinal cord injury repair

open access: yesInternational Journal of Extreme Manufacturing, 2023
Because of the complex nerve anatomy and limited regeneration ability of natural tissue, the current treatment effect for long-distance peripheral nerve regeneration and spinal cord injury (SCI) repair is not satisfactory.
Juqing Song   +4 more
doaj   +1 more source

Liquid Metal as Connecting or Functional Recovery Channel for the Transected Sciatic Nerve [PDF]

open access: yesarXiv, 2014
In this article, the liquid metal GaInSn alloy (67% Ga, 20.5% In, and 12.5% Sn by volume) is proposed for the first time to repair the peripheral neurotmesis as connecting or functional recovery channel. Such material owns a group of unique merits in many aspects, such as favorable fluidity, super compliance, high electrical conductivity, which are ...
arxiv  

Bioadhesive Graft-Antenna for Stimulation and Repair of Peripheral Nerves [PDF]

open access: yesarXiv, 2018
Peripheral nerve injuries are difficult to treat due to limited axon regeneration; brief electrical stimulation of injured nerves is an emerging therapy that can relieve pain and enhance regeneration. We report an original wireless stimulator based on a metal loop (diameter ~1 mm) that is powered by a transcranial magnetic stimulator (TMS).
arxiv  

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