Results 31 to 40 of about 60,696 (203)

Braf^V600ECA/+;Perk+/- tumors are dependent upon the remaining Perk allele.

, 2017
A) LY4 PERK inhibitor inhibits stress-dependent PERK signaling in cultured melanoma cells. B-C) Measurement of melanoma tumor volume B) and tumor weight C) in TyrCre+/-;BrafV600ECA/+;Perk +/- mice treated with LY-4; p-values analyzed by two-tailed ...
Yan Gao (93649), Serge Y. Fuchs (217962), Ireneusz Majsterek (3558608), Meenhard Herlyn (291309), Olga S. Chajewski (3558605), Akihiro Yoshida (713605), Dariusz Pytel (3558602), Maria C. G. Paredes (3558617), Kirk A. Staschke (569568), Yuliya V. Katlinskaya (3558614), J. Alan Diehl (3109995), Katarzyna Mackiewicz (362448), Shuo Qie (3110010), Gao Zhang (660886), Lawrence Wu (3558611)   +14 more
core   +1 more source

Bi-allelic Perk deletion abolishes Braf^V600ECA/+;Fbxo4+/- melanoma initiation, but Perk inhibition cannot recede tumor progression.

, 2017
A) Kaplan-Mayer survival curve of BrafV600ECA/+, Fbxo4 +/- and Perk +/+, +/- or -/- mice treated with 4-Hydroxytamoxifen (4-HT). B) Western blot of melanoma lysates from TyrCreCA/+; BrafV600ECA/+; Fbxo4 +/-; Perk +/+, Perk+/- or Perk-/- mice C) IHC ...
Yan Gao (93649), Serge Y. Fuchs (217962), Ireneusz Majsterek (3558608), Meenhard Herlyn (291309), Olga S. Chajewski (3558605), Akihiro Yoshida (713605), Dariusz Pytel (3558602), Maria C. G. Paredes (3558617), Kirk A. Staschke (569568), Yuliya V. Katlinskaya (3558614), J. Alan Diehl (3109995), Katarzyna Mackiewicz (362448), Shuo Qie (3110010), Gao Zhang (660886), Lawrence Wu (3558611)   +14 more
core   +1 more source

Akt is a PERK kinase.

, 2013
(A) Human PERK gene containing eight sequences that match the Akt consensus (RxRxxS/T) seven of which are located in its cytosolic domain (black bar). Green: Akt consensus sequence. Red/Yellow: Akt phosphorylation site.
Carolina Urrutia (438755), Daniela Pérez-Munizaga (438753), Alicia Grande (438756), Jennifer Alfaro (438759), Matías Blaustein (438752), Manuel Alejandro Sánchez (438754), Alejandro Colman-Lerner (438760), Guillermo Risso (438757), Anabella Srebrow (438758)   +8 more
core   +1 more source

pERK score in Spred2 immunostaining pattern.

, 2021
pERK score in Spred2 immunostaining pattern.
Li Chunning (11752069), Shinsuke Oda (11752066), Teizo Yoshimura (199118), Akihiro Matsukawa (197990), Takahiro Yamaguchi (602945), Masayoshi Fujisawa (5844029), Toshihiro Ito (197968)   +6 more
core   +1 more source

Inhibition of PERK pathway enhances sensitivity of human osteosarcoma HOS cells induced to pyropheophorbide-a methyl ester-mediated photodynamic therapy

Di-san junyi daxue xuebao, 2019
Objective To explore the role of RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) pathway in the crosstalk of apoptosis and autophagy in human osteosarcoma HOS cells induced by pyropheophorbide-a methyl ester-mediated photodynamic ...
ZHONG Shenxi, OU Yunsheng, CHEN Yanyang, YU Haoyang, ZUO Qiang   +4 more
doaj   +1 more source

PERK Pathway Dataset.

, 2013
PERK Pathway Dataset.
Min-Ho Jung (363898), Susan Bonner-Weir (217167), Lorella Marselli (179072), Gordon C. Weir (245807), Allison B. Goldfine (363899), Jeffrey Kennedy (363896), Dennis Sgroi (363902), Hitoshi Katsuta (363897), Ulysses J. Balis (363901)   +8 more
core   +1 more source

Ralph J. Perk, the “New ethnicity”, and the making of urban ethnic republicans [PDF]

, 2017
Historians seeking to explain the late twentieth century rightward shift of urban ethnic whites have tended to ignore the shifting meaning and content of white ethnic identity in this transition, and the utility of these changes to conservative political
JOE MERTON, Merton, Joe
core   +1 more source

Mscr.Dresd.App.2534,1-4603, Mscr.Dresd.App.2534.a,1-537 - Spezialkatalog zu den Nachlässen von Ernst Hassebrauk und Charlotte Hassebrauk [PDF]

, 2020
Zusammengestellt von Perk Loesch und Kerstin Schellbach in den Jahren 1990 und ...
Loesch, Perk, Schellbach, Kerstin
core   +2 more sources

Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.

PLoS ONE, 2014
BackgroundInsulin synthesis and cell proliferation are under tight regulation in pancreatic β-cells to maintain glucose homeostasis. Dysfunction in either aspect leads to development of diabetes.
Rong Wang, Elyse E Munoz, Siying Zhu, Barbara C McGrath, Douglas R Cavener   +4 more
doaj   +1 more source

Deletion of one Perk allele cooperates with Braf^V600E to drive metastatic melanoma.

, 2017
A) Kaplan-Mayer survival curve of TyrCre+/-;BrafV600ECA/+;Perk+/- mice treated with 4-HT. B) Western blot of melanoma skin lysates from TyrCre+/-;BrafV600ECA/+;Fbxo4;Perk +/+ or TyrCre+/-;BrafV600ECA/+;Perk+/- or Perk-/- mice (blot anti-Perk, p-eIF2α ...
Yan Gao (93649), Serge Y. Fuchs (217962), Ireneusz Majsterek (3558608), Meenhard Herlyn (291309), Olga S. Chajewski (3558605), Akihiro Yoshida (713605), Dariusz Pytel (3558602), Maria C. G. Paredes (3558617), Kirk A. Staschke (569568), Yuliya V. Katlinskaya (3558614), J. Alan Diehl (3109995), Katarzyna Mackiewicz (362448), Shuo Qie (3110010), Gao Zhang (660886), Lawrence Wu (3558611)   +14 more
core   +1 more source