Results 31 to 40 of about 59,057 (299)
PERK and filamin A in actin cytoskeleton remodeling at ER-plasma membrane contact sites
Molecular & Cellular Oncology, 2017 The endoplasmic reticulum (ER) stress sensor protein kinase RNA-like endoplasmic reticulum kinase (PERK) plays a major role during the unfolded protein response (UPR), mainly through eIF2α phosphorylation.
Alexander R. van Vliet +1 more
doaj +1 more source
The Prognostic Value of PERK in Cancer and Its Relationship With Immune Cell Infiltration
Frontiers in Molecular Biosciences, 2021 Background: Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is a type I transmembrane protein that functions as an endoplasmic reticulum (ER) stress sensor to regulate global protein synthesis.
Peng Wang +6 more
doaj +1 more source
PERK pathway activation in heart.
, 2014 The protein levels of p-PERK, PERK, p-eIF2α, eIF2α.
Hanpeng Huang (549638) +6 more
core +1 more source
Modulation of Perk dosage using Perk+/− mice impacted glucose homeostasis.
, 2014 A. Random fed serum glucose of mice at 15–36 postnatal days. Mice are in mixed genetic background.
Elyse E. Munoz (575799) +4 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BrafV600ECA/+;Perk+/- tumors are dependent upon the remaining Perk allele.
, 2017 A) LY4 PERK inhibitor inhibits stress-dependent PERK signaling in cultured melanoma cells. B-C) Measurement of melanoma tumor volume B) and tumor weight C) in TyrCre+/-;BrafV600ECA/+;Perk +/- mice treated with LY-4; p-values analyzed by two-tailed ...
Yan Gao (93649) +14 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Precipitation Simulations of the O‐Phase in Ti2AlNb Alloys Processed by Laser Powder Bed Fusion
Advanced Engineering Materials, EarlyView.Simulated and experimental evolution of the O‐phase volume fraction during postprocessing of a Ti‐21Al‐25Nb (at.%) alloy processed by laser powder bed fusion. With results of sensitivity to input parameters from a thorough and quantified analysis, the interfacial energy matrix/precipitate is the most relevant input parameter for the simulation of the O‐
Silvana Tumminello +7 more
wiley +1 more source
Botaanika-alased tööd. III, Taimefüsioloogia-alaseid töid = Труды по ботанике. Труды по физиологии растений [PDF]
, 1960 • А. Перк. Исследования по физиологии растений, проводимые на кафедре физиологии растений Тартуского государственного университета • А. Perk. Taimefüsioloogilised uurimistööd TRÜ taimefüsioloogia kateedris • Perk.
Tartu Ülikool
core
, 2013 (A) Human PERK gene containing eight sequences that match the Akt consensus (RxRxxS/T) seven of which are located in its cytosolic domain (black bar). Green: Akt consensus sequence. Red/Yellow: Akt phosphorylation site.
Carolina Urrutia (438755) +8 more
core +1 more source