Results 61 to 70 of about 60,696 (203)

PERK-mediated phosphorylation of eIF2α causes elimination of rer1 mutant cells.

(A-D) Third-instar wing epithelium containing hs-FLP-induced MARCM clones (72 hrs AHS), of following genotypes, (A) UAS-GFP (rer1+/+), (B) UAS-GFP, rer1–/–, (C) UAS-GFP, rer1–/–+ UAS-PERK RNAi and (D) UAS-GFP, rer1–/–+ UAS-GCN2 RNAi, stained with the ...
Shruti Umarvaish (18056496), Shivani Bajaj (18056499), Varun Chaudhary (37352), Hrudya Mohan (18056505), Pranab Kumar Paul (18056493), Rishana Farin S. (18056502), Wim Annaert (29167)   +6 more
core   +1 more source

Florham Perk Coffee House

, 2003
The Florham Perk Coffee House, located in the Florham Student ...

core   +1 more source

ER stress sensor PERK drives ferroptosis by disrupting MAMs-mediated mitochondrial homeostasis and promoting mtROS accumulation in acute myocardial infarction

Pharmacological Research
Acute myocardial infarction (AMI) is a life-threatening condition in which ferroptosis represents an important form of regulated cardiomyocyte death, yet its upstream regulatory mechanisms remain incompletely understood.
Xueshu Tao, Yunxiang Zhang, Jiao Pang, Zihan Liao, Gaohan Chen, Xue Zhong, Xingrui Cao, Ying Lin, Dawei Guan, Yuan Tian, Liang Hao, Rui Zhao, Zhipeng Cao   +12 more
doaj   +1 more source

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

eLife, 2017
Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR).
Guangyan Xiong, Sajedah M Hindi, Aman K Mann, Yann S Gallot, Kyle R Bohnert, Douglas R Cavener, Scott R Whittemore, Ashok Kumar   +7 more
doaj   +1 more source

Modulation Of PERK Signalling During Neurodegeneration

, 2019
Numerous neurodegenerative diseases are characterised by the aggregation of misfolded disease-specific proteins in the brain. This is often associated with increased activation of the unfolded protein response (UPR), particularly the PKR-like Endoplasmic
Daniel T. Hughes (7785638)
core  

pERK inhibition percentages in treated cell line.

, 2016
pERK inhibition percentages in treated cell line.
Saverio Candido (2576455), James A. McCubrey (420774), Santo Motta (341564), Ferdinando Nicoletti (89733), Giulia Russo (11921), Massimo Libra (56131), Francesco Pappalardo (341561), Marzio Pennisi (341563), Salvatore Cavalieri (2576452)   +8 more
core   +1 more source

OSMAN ENGİN'İN "DEUTSCHLAND ALLEIN ZU HAUS" VE HATİCE AKYÜN'ÜN "EINMAL HANS MIT SCHARFER SOßE" ESERLERİNDE KALIP YARGILAR

Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi, 2019
Yabancı kavramı genel olarak başka bir milletten olan, bilinmeyen, henüz keşfedilmeyen ve hakkında bilgi sahip olunmayan olgular için kullanılmaktadır.
Derya Perk
doaj  

Klf5 suppresses pERK in mouse ESCs.

, 2018
(A) Schematic representation of Klf5 targeting vector to create Klf5-KO ESCs. (B) Expression of Klf5 protein in WT and Klf5-KO ESCs. Scale bar: 100 μm. (C) Western blot analysis of WT, Klf5 heterozygous, and Klf5-KO ESCs.
Satoru Takahashi (32871), Ken Matsumoto (47689), Hitoshi Niwa (7709), Masafumi Muratani (4760067), Hyojung Jeon (2550952), Masatsugu Ema (200616), Tsuyoshi Waku (2550955), Takuya Azami (2550946)   +7 more
core   +1 more source

Insulin transcription was up-regulated in P17 Perk^+/− mice.

, 2014
A. Gene expression levels of mouse islets relative to Perk+/+. Mice are postnatal 17 days. Shown are means ± SEM.
Elyse E. Munoz (575799), Barbara C. McGrath (210345), Douglas R. Cavener (210348), Rong Wang (59795), Siying Zhu (459098)   +4 more
core   +1 more source

Loss of TRIM29 mitigates viral myocarditis by attenuating PERK-driven ER stress response in male mice

Nature Communications
Viral myocarditis, an inflammatory disease of the myocardium, is a significant cause of sudden death in children and young adults. The current coronavirus disease 19 pandemic emphasizes the need to understand the pathogenesis mechanisms and potential ...
Junying Wang, Wenting Lu, Jerry Zhang, Yong Du, Mingli Fang, Ao Zhang, Gabriel Sungcad, Samantha Chon, Junji Xing   +8 more
doaj   +1 more source