Results 251 to 260 of about 358,024 (354)

Peroxisomes, PPARs, and Their Role in Macrophages. [PDF]

Cells
Pratama AM, Bömmel H, Wihadmadyatami H, Tjahjono Y, Ergün S, Bachhuka A, Karnati S.   +6 more
europepmc   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Fatty Liver in Fish: Metabolic Drivers, Molecular Pathways and Physiological Solutions. [PDF]

Animals (Basel)
Xie X, Zhang C, Zulfahmi I, Mbokane E, Cao Q.   +4 more
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Lipidomics analysis of phospholipid profiles and oxidative stability in pan-fried beef patties incorporating sacha inchi leaf extracts. [PDF]

Sci Rep
Harlina PW, Nawaz A, Sabrina SA, Nur'isma EA, Geng F, Shahzad R, Rafi M, Maritha V, Yudhistira B, Al-Baarri AN, Arifin HR, Subroto E, Lembong E, Yarlina VP.   +13 more
europepmc   +1 more source

Differential effects of apelin-13 on lipid peroxidation and DNA oxidation in doxorubicin-treated rats: A preliminary study

Katarzyna Matusik, Katarzyna Kamińska, Kaja Kasarełło, Agnieszka Cudnoch-Jędrzejewska   +3 more
openalex   +2 more sources

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Statistical and Multivariate Evaluation of Olive Oil Degradation During Long-Term Storage. [PDF]

Foods
Almeida ES, Silva DF, de Oliveira NS, Fernandes JS, Oliveira BCS, Monteiro S, Almeida FV, Braga JWB, Dias ACB.   +8 more
europepmc   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

The Effect of Borage Seed Oil (<i>Borago officinalis</i> L.) and Matcha Tea Powder (<i>Camellia sinensis</i> L.) on the Physicochemical Properties, Oxidative Stability, Color, and Tenderness of Vacuum-Packed Lamb Meatloaf During Storage. [PDF]

Foods
Latoch A, Libera J, Öncül N, Metli M.
europepmc   +1 more source