Results 131 to 140 of about 4,690,509 (242)

Analysis of Person-organization Fit and Person-organization Misfit in Ernst & Young Indonesia [PDF]

open access: yes, 2013
Person-Organization Fit, commonly described as the resemblance of person's values and organization values, is one of the crucial factors in determining the success of an organization.
Wowor, K. (Kristin)
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Associations between person-environment fit and mental health - results from the population-based LIFE-Adult-Study

open access: yesBMC Public Health
Within occupational settings, mental health of employees can be affected by complex interactions between individuals and their work environment. The aim of this cross-sectional analysis was to investigate the association between person-environment fit ...
Franziska U. Jung   +13 more
doaj   +1 more source

Analisis Pengaruh Person-Organization Fit dan Person-Job fit terhadap Kinerja Karyawan [PDF]

open access: yes
Person-Organization fit has provided a deep understanding of increasing the fit between employees and the organization, retaining employees in the long term by increasing employee satisfaction and commitment to the company, as well as improving ...
Niken Permata Sari   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The relationship between perceived sufficiency of HRM practices, person-organization fit, person-job fit and anxiety

open access: yes, 2009
nsan Kaynakları Uygulamalarının Algılanan Yeterliliği, Kişi-Kurum Uyumu, Kişi-İş Uyumu, Kaygı ÖZET İNSAN KAYNAKLARI UYGULAMALARININ ALGILANAN YETERLİLİĞİ, KİŞİ-KURUM UYUMU, KİŞİ-İŞ UYUMU VE KAYGI ARASINDAKİ İLİŞKİLER Bu araştırmanın temel hedefi, İnsan ...
Yaşar, Neslihan
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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