Results 31 to 40 of about 2,457 (145)

Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report

open access: yesCase Reports in Infectious Diseases, Volume 2021, Issue 1, 2021., 2021
Pertussis is a vaccine‐preventable disease with an incidence that has been trending upwards in the United States over the last two decades. This is evident by an increase in the incidence from 10,100 cases in 1974 to a peak of >48,000 cases noted in the last decade.
Patrick Ovie Fueta   +4 more
wiley   +1 more source

Changes in genetic diversity of the Bordetella pertussis population in Serbia between 1953 and 2011 [PDF]

open access: yesArchives of Biological Sciences, 2014
Mass vaccination has significantly reduced the incidence of pertussis, however, the disease is re-emerging, even in some countries with high vaccination coverage. In Serbia, whole cell pertussis vaccine was introduced in 1957. To monitor changes
Plješa Tatjana   +5 more
doaj   +1 more source

DegP Chaperone Suppresses Toxic Inner Membrane Translocation Intermediates. [PDF]

open access: yesPLoS ONE, 2016
The periplasm of Gram-negative bacteria includes a variety of molecular chaperones that shepherd the folding and targeting of secreted proteins. A central player of this quality control network is DegP, a protease also suggested to have a chaperone ...
Esther Braselmann   +3 more
doaj   +1 more source

Analysis of Bordetella pertussis pertactin and pertussis toxin types from Queensland, Australia, 1999–2003

open access: yesBMC Infectious Diseases, 2006
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj   +1 more source

Crucial role of antibodies to pertactin in Bordetella pertussis immunity [PDF]

open access: yes, 2003
Pertussis, a serious infectious disease of the respiratory tract caused by Bordetella pertussis, is reemerging in vaccinated populations. Efforts to curtail this disease are hampered by limited insight into the basis of protective immunity ...
Hellwig, SMM   +4 more
core   +2 more sources

Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan

open access: yesEmerging Infectious Diseases, 2017
Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014–2016 (8%) was significantly lower than the frequency in 2005–2007 (41 ...
Yukihiro Hiramatsu   +5 more
doaj   +1 more source

Role of Evolutionary Selection Acting on Vaccine Antigens in the Re-Emergence of Bordetella Pertussis

open access: yesDiseases, 2019
Pertussis (“whooping cough”) is a re-emerging disease with increasing incidence among fully vaccinated individuals. We explored the genetic diversity of five Bordetella pertussis proteins used to generate the subunit vaccine across ancestral and newly ...
Haley Etskovitz   +3 more
doaj   +1 more source

ALEPH: a network‐oriented approach for the generation of fragment‐based libraries and for structure interpretation

open access: yesActa Crystallographica Section D, Volume 76, Issue 3, Page 193-208, March 2020., 2020
ALEPH characterizes the main‐chain geometry of small, noncontinuous fragments to flexibly annotate secondary structure, decompose folds, extract libraries and superpose fragments. Secondary and tertiary structure are described through networks of characteristic vectors, which are defined between the centroids of the Cα and carbonyl O atoms in a peptide.
Ana Medina   +5 more
wiley   +1 more source

Protective Activity and Safety of Acellular Pertussis Vaccine from Vaccine and Freshly Isolated Strain Bordetella pertussis

open access: yesЭпидемиология и вакцинопрофилактика, 2017
Goal. Study of the protective activity and safety of acellular pertussis vaccine (APV) using freshly isolated strain of B. pertussis. Materials and methods. Mice-hybrids F1 (CBAxC57Bl6). The B. pertussis strains: vaccine strains No. 305, No. 203, freshly
E. M. Zaitsev   +2 more
doaj   +1 more source

Development and Validation of a Bordetella pertussis Whole‐Genome Screening Strategy

open access: yesJournal of Immunology Research, Volume 2020, Issue 1, 2020., 2020
The immune response elicited by the protective whole‐cell pertussis (wP) versus the less‐protective acellular pertussis (aP) vaccine has been well characterized; however, important clinical problems remain unsolved, as the inability of the currently administered aP vaccine is resulting in the reemergence of clinical disease (i.e., whooping cough ...
Ricardo da Silva Antunes   +10 more
wiley   +1 more source

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