Changes in genetic diversity of the Bordetella pertussis population in Serbia between 1953 and 2011 [PDF]
Mass vaccination has significantly reduced the incidence of pertussis, however, the disease is re-emerging, even in some countries with high vaccination coverage. In Serbia, whole cell pertussis vaccine was introduced in 1957. To monitor changes
Plješa Tatjana +5 more
doaj +1 more source
Objective: To detect and characterize pertactin-negative Bordetella pertussis in Canada, especially for isolates collected in recent years. Methods: A total of 224 isolates from the years 1994–2013 were screened by Western immuno-blot for expression of ...
Raymond S.W. Tsang +8 more
doaj +1 more source
DegP Chaperone Suppresses Toxic Inner Membrane Translocation Intermediates. [PDF]
The periplasm of Gram-negative bacteria includes a variety of molecular chaperones that shepherd the folding and targeting of secreted proteins. A central player of this quality control network is DegP, a protease also suggested to have a chaperone ...
Esther Braselmann +3 more
doaj +1 more source
Increase in pertussis cases along with high prevalence of two emerging genotypes of Bordetella pertussis in Perú, 2012 [PDF]
As has occurred in many regions worldwide, in 2012 the incidence of pertussis increased in Perú. This epidemiologic situation has been associated with a waning vaccine-induced immunity and the adaptation of Bordetella pertussis to vaccine-induced ...
Bailon, H +3 more
core +3 more sources
Severe pertussis infection in infants less than 6 months of age: clinical manifestations and molecular characterization [PDF]
We conducted a study to determine the main traits of pertussis among unimmunized infants less than 6 months of age. From August 2012 to March 2015, 141 nasopharyngeal aspirates (NPAs) were collected from infants with respiratory symptoms attending 2
Buttinelli, Gabriele +12 more
core +1 more source
Bordetella parapertussis isolates not expressing pertactin circulating in France [PDF]
Surprisingly, most Bordetella parapertussis isolates collected in France since 2007 do not express pertactin, owing to mutations in the structural gene encoding this protein. We used a 454 pyrosequencing strategy to study and compare the genetics of two B.
Bouchez, Valérie +4 more
openaire +2 more sources
Crucial Role of Antibodies to Pertactin inBordetella pertussisImmunity [PDF]
Pertussis, a serious infectious disease of the respiratory tract caused by Bordetella pertussis, is reemerging in vaccinated populations. Efforts to curtail this disease are hampered by limited insight into the basis of protective immunity. Opsonophagocytosis was recently found to play a central role in cellular bactericidal activity against B ...
Hellwig, Sandra M. M. +4 more
openaire +6 more sources
Analysis of Bordetella pertussis populations in European countries with different vaccination policies. [PDF]
Despite the widespread use of pertussis vaccines during the last decades, pertussis has remained an endemic disease with frequent epidemic outbreaks. Currently two types of vaccines are used: whole-cell vaccines (WCVs) and recently developed acellular ...
Amersfoorth, S C M van +14 more
core +1 more source
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj +1 more source
Membrane vesicles derived from Bordetella bronchiseptica: Active constituent of a new vaccine against infections caused by this pathogen [PDF]
Bordetella bronchiseptica, a Gram-negative bacterium, causes chronic respiratory tract infections in a wide variety of mammalian hosts, including humans (albeit rarely).
Bartel, Erika Belén +5 more
core +2 more sources

