Results 31 to 40 of about 2,457 (145)
Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
Pertussis is a vaccine‐preventable disease with an incidence that has been trending upwards in the United States over the last two decades. This is evident by an increase in the incidence from 10,100 cases in 1974 to a peak of >48,000 cases noted in the last decade.
Patrick Ovie Fueta +4 more
wiley +1 more source
Changes in genetic diversity of the Bordetella pertussis population in Serbia between 1953 and 2011 [PDF]
Mass vaccination has significantly reduced the incidence of pertussis, however, the disease is re-emerging, even in some countries with high vaccination coverage. In Serbia, whole cell pertussis vaccine was introduced in 1957. To monitor changes
Plješa Tatjana +5 more
doaj +1 more source
DegP Chaperone Suppresses Toxic Inner Membrane Translocation Intermediates. [PDF]
The periplasm of Gram-negative bacteria includes a variety of molecular chaperones that shepherd the folding and targeting of secreted proteins. A central player of this quality control network is DegP, a protease also suggested to have a chaperone ...
Esther Braselmann +3 more
doaj +1 more source
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj +1 more source
Crucial role of antibodies to pertactin in Bordetella pertussis immunity [PDF]
Pertussis, a serious infectious disease of the respiratory tract caused by Bordetella pertussis, is reemerging in vaccinated populations. Efforts to curtail this disease are hampered by limited insight into the basis of protective immunity ...
Hellwig, SMM +4 more
core +2 more sources
Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan
Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014–2016 (8%) was significantly lower than the frequency in 2005–2007 (41 ...
Yukihiro Hiramatsu +5 more
doaj +1 more source
Pertussis (“whooping cough”) is a re-emerging disease with increasing incidence among fully vaccinated individuals. We explored the genetic diversity of five Bordetella pertussis proteins used to generate the subunit vaccine across ancestral and newly ...
Haley Etskovitz +3 more
doaj +1 more source
ALEPH characterizes the main‐chain geometry of small, noncontinuous fragments to flexibly annotate secondary structure, decompose folds, extract libraries and superpose fragments. Secondary and tertiary structure are described through networks of characteristic vectors, which are defined between the centroids of the Cα and carbonyl O atoms in a peptide.
Ana Medina +5 more
wiley +1 more source
Goal. Study of the protective activity and safety of acellular pertussis vaccine (APV) using freshly isolated strain of B. pertussis. Materials and methods. Mice-hybrids F1 (CBAxC57Bl6). The B. pertussis strains: vaccine strains No. 305, No. 203, freshly
E. M. Zaitsev +2 more
doaj +1 more source
Development and Validation of a Bordetella pertussis Whole‐Genome Screening Strategy
The immune response elicited by the protective whole‐cell pertussis (wP) versus the less‐protective acellular pertussis (aP) vaccine has been well characterized; however, important clinical problems remain unsolved, as the inability of the currently administered aP vaccine is resulting in the reemergence of clinical disease (i.e., whooping cough ...
Ricardo da Silva Antunes +10 more
wiley +1 more source

