Results 51 to 60 of about 3,408 (187)

Isolate-Based Surveillance of Bordetella pertussis, Austria, 2018–2020

Emerging Infectious Diseases, 2021
Pertussis is a vaccine-preventable disease, and its recent resurgence might be attributable to the emergence of strains that differ genetically from the vaccine strain.
Adriana Cabal, Daniela Schmid, Markus Hell, Ali Chakeri, Elisabeth Mustafa-Korninger, Alexandra Wojna, Anna Stöger, Johannes Möst, Eva Leitner, Patrick Hyden, Thomas Rattei, Adele Habington, Ursula Wiedermann, Franz Allerberger, Werner Ruppitsch   +14 more
doaj   +1 more source

Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics

mSphere, 2016
During 2010 and 2012, California and Vermont, respectively, experienced statewide epidemics of pertussis with differences seen in the demographic affected, case clinical presentation, and molecular epidemiology of the circulating strains.
Katherine E. Bowden, Michael R. Weigand, Yanhui Peng, Pamela K. Cassiday, Scott Sammons, Kristen Knipe, Lori A. Rowe, Vladimir Loparev, Mili Sheth, Keeley Weening, M. Lucia Tondella, Margaret M. Williams   +11 more
doaj   +1 more source

Pertactin-Negative Bordetella pertussis Strains: Evidence for a Possible Selective Advantage [PDF]

Clinical Infectious Diseases, 2014
A recent increase in Bordetella pertussis without the pertactin protein, an acellular vaccine immunogen, has been reported in the United States. Determining whether pertactin-deficient (PRN(-)) B. pertussis is evading vaccine-induced immunity or altering the severity of illness is needed.We retrospectively assessed for associations between pertactin ...
Stacey W, Martin, Lucia, Pawloski, Margaret, Williams, Keeley, Weening, Chas, DeBolt, Xuan, Qin, Laura, Reynolds, Cynthia, Kenyon, Gregory, Giambrone, Kathy, Kudish, Lisa, Miller, David, Selvage, Adria, Lee, Tami H, Skoff, Hajime, Kamiya, Pamela K, Cassiday, Maria L, Tondella, Thomas A, Clark   +17 more
openaire   +2 more sources

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015 [PDF]

Eurosurveillance, 2019
Introduction Pertussis outbreaks have occurred in several industrialised countries using acellular pertussis vaccines (ACVs) since the 1990s. High prevalence of pertactin (PRN)-deficient Bordetella pertussis isolates has been found in these countries. Aims
Barkoff, Alex-Mikael, Mertsola, Jussi, Pierard, Denis, Dalby, Tine, Høgh, Silje Vermedal, Guillot, Sophie, Stefanelli, Paola, van Gent, Marjolein, Berbers, Guy, Vestrheim, Didrik Frimann, Greve-Isdahl, Margrethe, Wehlin, Lena, Ljungman, Margaretha, Fry, Norman K., Markey, Kevin, He, Qiushui   +15 more
openaire   +6 more sources

Pertactin Is Required forBordetellaSpecies To Resist Neutrophil-Mediated Clearance [PDF]

Infection and Immunity, 2010
ABSTRACTPertactin (PRN) is an autotransporter protein produced by all members of theBordetella bronchisepticacluster, which includesB. pertussis,B. parapertussis, andB. bronchiseptica. It is a primary component of acellular pertussis vaccines, and anti-PRN antibody titers correlate with protection.In vitrostudies have suggested that PRN functions as an
Carol S, Inatsuka, Qian, Xu, Ivan, Vujkovic-Cvijin, Sandy, Wong, Scott, Stibitz, Jeff F, Miller, Peggy A, Cotter   +6 more
openaire   +2 more sources

Changes in Predominance of Pulsed-Field Gel Electrophoresis Profiles of Bordetella pertussis Isolates, United States, 2000–2012

Emerging Infectious Diseases, 2016
To clarify the characteristics of circulating Bordetella pertussis isolates, we used pulsed-field gel electrophoresis (PFGE) to analyze 5,262 isolates collected in the United States during 2000–2012.
Pamela K. Cassiday, Tami H. Skoff, Selina Jawahir, M. Lucia Tondella   +3 more
doaj   +1 more source

Fha Deficient Bordetella pertussis Isolates in Iran with 50 Years Whole Cell Pertussis Vaccination

Iranian Journal of Public Health, 2021
Background: Bordetella pertussis, a highly contagious respiratory. Notably, the resurgence of pertussis has recently been associated with the lacking production of vaccine virulence factors.
Samaneh Saedi, Azadeh Safarchi, Faranak Tayebzadeh Moghadam, Siamak Heidarzadeh, Vajihe Sadat Nikbin, Fereshteh Shahcheraghi   +5 more
doaj   +1 more source

isolates in Finland: Serotype and fimbrial expression [PDF]

, 2008
Background Bordetella pertussis causes whooping cough or pertussis in humans. It produces several virulence factors, of which the fimbriae are considered adhesins and elicit immune responses in the host. B.
Eriikka Heikkinen, Dorothy K Xing, Rose-Marie Olander, Jukka Hytonen, Matti K Viljanen, Jussi Mertsola, Qiushui He   +6 more
core   +1 more source

Acellular Pertussis Vaccine Components: Today and Tomorrow

Vaccines, 2020
Pertussis is a highly communicable acute respiratory infection caused by Bordetella pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks occur cyclically worldwide and effective vaccination strategies are needed
Kalyan K. Dewan, Bodo Linz, Susan E. DeRocco, Eric T. Harvill   +3 more
doaj   +1 more source

Acellular Pertussis Vaccine from Antigens of Freshly Isolated and Vaccine Strains of Bordetella pertussis with Different Genotypic Characteristics

Эпидемиология и вакцинопрофилактика, 2021
Relevance. The development of effective and safe vaccines for pertussis prevention remains an urgent public health challenge.Aim. To study the protective activity and safety of acellular pertussis vaccine (AcPV) containing a complex of protective ...
E. M. Zaitsev, I. G. Bazhanova, M. V. Britsina, N. U. Mertsalova, M. N. Ozeretskovskaya   +4 more
doaj   +1 more source