Results 51 to 60 of about 2,565 (197)
Cardiopulmonary Arrest and Pulmonary Hypertension in an Infant with Pertussis Case Report
Case Reports in Infectious Diseases, Volume 2021, Issue 1, 2021., 2021 Pertussis is a vaccine‐preventable disease with an incidence that has been trending upwards in the United States over the last two decades. This is evident by an increase in the incidence from 10,100 cases in 1974 to a peak of >48,000 cases noted in the last decade.
Patrick Ovie Fueta +4 more
wiley +1 more source
Vaccines, 2023 There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present ethical concerns. The development of relevant in vitro assays is part of the solution.
Jason Szeto +17 more
doaj +1 more source
Changes in genetic diversity of the Bordetella pertussis population in Serbia between 1953 and 2011 [PDF]
Archives of Biological Sciences, 2014 Mass vaccination has significantly reduced the incidence of pertussis, however, the disease is re-emerging, even in some countries with high vaccination coverage. In Serbia, whole cell pertussis vaccine was introduced in 1957. To monitor changes
Plješa Tatjana +5 more
doaj +1 more source
DegP Chaperone Suppresses Toxic Inner Membrane Translocation Intermediates. [PDF]
PLoS ONE, 2016 The periplasm of Gram-negative bacteria includes a variety of molecular chaperones that shepherd the folding and targeting of secreted proteins. A central player of this quality control network is DegP, a protease also suggested to have a chaperone ...
Esther Braselmann +3 more
doaj +1 more source
Screening pertactin-specific antibodies and evaluating competitive epitope recognition by native mass spectrometry. [PDF]
Chem SciGadallah MI +6 more
europepmc +3 more sources
BMC Infectious Diseases, 2006 Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj +1 more source
Acellular pertussis vaccines and the role of pertactin and fimbriae
Expert Review of Vaccines, 2007 The introduction of acellular pertussis (Pa) vaccines in countries with a low uptake of whole-cell pertussis (Pw) vaccines has led to a dramatic reduction in pertussis disease. Diphtheria-tetanus-acellular pertussis (DTPa) vaccines have also ensured continued high level disease protection in these countries following the shift from Pw- to Pa-containing
Jan T, Poolman, Hans O, Hallander
openaire +2 more sources
Acta Crystallographica Section D, Volume 76, Issue 3, Page 193-208, March 2020., 2020 ALEPH characterizes the main‐chain geometry of small, noncontinuous fragments to flexibly annotate secondary structure, decompose folds, extract libraries and superpose fragments. Secondary and tertiary structure are described through networks of characteristic vectors, which are defined between the centroids of the Cα and carbonyl O atoms in a peptide.
Ana Medina +5 more
wiley +1 more source
Development and Validation of a Bordetella pertussis Whole‐Genome Screening Strategy
Journal of Immunology Research, Volume 2020, Issue 1, 2020., 2020 The immune response elicited by the protective whole‐cell pertussis (wP) versus the less‐protective acellular pertussis (aP) vaccine has been well characterized; however, important clinical problems remain unsolved, as the inability of the currently administered aP vaccine is resulting in the reemergence of clinical disease (i.e., whooping cough ...
Ricardo da Silva Antunes +10 more
wiley +1 more source
Diseases, 2019 Pertussis (“whooping cough”) is a re-emerging disease with increasing incidence among fully vaccinated individuals. We explored the genetic diversity of five Bordetella pertussis proteins used to generate the subunit vaccine across ancestral and newly ...
Haley Etskovitz +3 more
doaj +1 more source