Results 41 to 50 of about 2,457 (145)

Isolate-Based Surveillance of Bordetella pertussis, Austria, 2018–2020

Emerging Infectious Diseases, 2021
Pertussis is a vaccine-preventable disease, and its recent resurgence might be attributable to the emergence of strains that differ genetically from the vaccine strain.
Adriana Cabal, Daniela Schmid, Markus Hell, Ali Chakeri, Elisabeth Mustafa-Korninger, Alexandra Wojna, Anna Stöger, Johannes Möst, Eva Leitner, Patrick Hyden, Thomas Rattei, Adele Habington, Ursula Wiedermann, Franz Allerberger, Werner Ruppitsch   +14 more
doaj   +1 more source

Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics

mSphere, 2016
During 2010 and 2012, California and Vermont, respectively, experienced statewide epidemics of pertussis with differences seen in the demographic affected, case clinical presentation, and molecular epidemiology of the circulating strains.
Katherine E. Bowden, Michael R. Weigand, Yanhui Peng, Pamela K. Cassiday, Scott Sammons, Kristen Knipe, Lori A. Rowe, Vladimir Loparev, Mili Sheth, Keeley Weening, M. Lucia Tondella, Margaret M. Williams   +11 more
doaj   +1 more source

Purification design and practice for pertactin, the third component of acellular pertussis vaccine, from Bordetella pertussis

, 2016
Development of acellular pertussis vaccine (aPV) requires purification of several components from Bordetella pertussis. While the components pertussis toxin (PT) and filamentous hemagglutinin (FHA) have been successfully purified, the third component ...
Li, Zenglan, Zhang, Songping, Li, Zhengjun, Zhang, Guifeng, Wang, Qi, Zhang, Yan, Ma, Guanghui, Su, Zhiguo, Liu, Yongdong, Luo, Jian   +9 more
core   +1 more source

Crucial role of antibodies to pertactin in Bordetella pertussis immunity [PDF]

, 2003
Pertussis, a serious infectious disease of the respiratory tract caused by Bordetella pertussis, is reemerging in vaccinated populations. Efforts to curtail this disease are hampered by limited insight into the basis of protective immunity ...
Rodríguez, María Eugenia, Mooi, Frits R., Hellwig, Sandra M. M., Berbers, Guy A. M., Winkel, Jan G. J. van de   +4 more
core   +1 more source

Changes in Predominance of Pulsed-Field Gel Electrophoresis Profiles of Bordetella pertussis Isolates, United States, 2000–2012

Emerging Infectious Diseases, 2016
To clarify the characteristics of circulating Bordetella pertussis isolates, we used pulsed-field gel electrophoresis (PFGE) to analyze 5,262 isolates collected in the United States during 2000–2012.
Pamela K. Cassiday, Tami H. Skoff, Selina Jawahir, M. Lucia Tondella   +3 more
doaj   +1 more source

Fha Deficient Bordetella pertussis Isolates in Iran with 50 Years Whole Cell Pertussis Vaccination

Iranian Journal of Public Health, 2021
Background: Bordetella pertussis, a highly contagious respiratory. Notably, the resurgence of pertussis has recently been associated with the lacking production of vaccine virulence factors.
Samaneh Saedi, Azadeh Safarchi, Faranak Tayebzadeh Moghadam, Siamak Heidarzadeh, Vajihe Sadat Nikbin, Fereshteh Shahcheraghi   +5 more
doaj   +1 more source

Acellular Pertussis Vaccine Components: Today and Tomorrow

Vaccines, 2020
Pertussis is a highly communicable acute respiratory infection caused by Bordetella pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks occur cyclically worldwide and effective vaccination strategies are needed
Kalyan K. Dewan, Bodo Linz, Susan E. DeRocco, Eric T. Harvill   +3 more
doaj   +1 more source

AF‐CALVADOS: AlphaFold‐guided simulations of multi‐domain proteins at the proteome level

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Deep‐learning methods have transformed our ability to predict the three‐dimensional structures of folded proteins from sequence, and coarse‐grained simulations have made it possible to study intrinsically disordered proteins at the proteome scale. More than half of human proteins, however, contain mixtures of disordered regions and one or more
Sören von Bülow, Kristoffer E. Johansson, Kresten Lindorff‐Larsen   +2 more
wiley   +1 more source

Pertactin-deficient isolates: evidence of increased circulation in Europe, 1998 to 2015. [PDF]

, 2019
IntroductionPertussis outbreaks have occurred in several industrialised countries using acellular pertussis vaccines (ACVs) since the 1990s.
Berbers, Guy, Markey, Kevin, Høgh, Silje Vermedal, Stefanelli, Paola, Wehlin, Lena, Vestrheim, Didrik, van Gent, Marjolein, Fry, Norman K., Mertsola, Jussi, Barkoff, Alex-Mikael, Pierard, Denis, Guillot, Sophie, Fry, Norman K, Dalby, Tine, Greve-Isdahl, Margrethe, Barkoff, Alex Mikael, Vestrheim, Didrik Frimann, He, Qiushui, Hoegh, Silje Vermedal, Ljungman, Margaretha   +19 more
core   +1 more source

Acellular Pertussis Vaccine from Antigens of Freshly Isolated and Vaccine Strains of Bordetella pertussis with Different Genotypic Characteristics

Эпидемиология и вакцинопрофилактика, 2021
Relevance. The development of effective and safe vaccines for pertussis prevention remains an urgent public health challenge.Aim. To study the protective activity and safety of acellular pertussis vaccine (AcPV) containing a complex of protective ...
E. M. Zaitsev, I. G. Bazhanova, M. V. Britsina, N. U. Mertsalova, M. N. Ozeretskovskaya   +4 more
doaj   +1 more source