Results 61 to 70 of about 2,565 (197)

Simple Algorithm for Identification of Bordetella pertussis Pertactin Gene Variants [PDF]

Journal of Clinical Microbiology, 2004
ABSTRACT Studies performed in several countries have demonstrated the recent emergence and subsequent dominance of circulating Bordetella pertussis strains harboring pertactin and pertussis toxin variants not included in pertussis vaccines. Determination of the pertactin gene variants is commonly performed
Muyldermans, G, Pierard, D, Hoebekx, N, Advani, R, van Amersfoorth, S, de Schutter, I, Soetens, O, Eeckhout, L, Malfroot, A, Lauwers, S   +9 more
openaire   +4 more sources

Protective Activity and Safety of Acellular Pertussis Vaccine from Vaccine and Freshly Isolated Strain Bordetella pertussis

Эпидемиология и вакцинопрофилактика, 2017
Goal. Study of the protective activity and safety of acellular pertussis vaccine (APV) using freshly isolated strain of B. pertussis. Materials and methods. Mice-hybrids F1 (CBAxC57Bl6). The B. pertussis strains: vaccine strains No. 305, No. 203, freshly
E. M. Zaitsev, I. G. Bazhanova, M. V. Britsina   +2 more
doaj   +1 more source

Isolate-Based Surveillance of Bordetella pertussis, Austria, 2018–2020

Emerging Infectious Diseases, 2021
Pertussis is a vaccine-preventable disease, and its recent resurgence might be attributable to the emergence of strains that differ genetically from the vaccine strain.
Adriana Cabal, Daniela Schmid, Markus Hell, Ali Chakeri, Elisabeth Mustafa-Korninger, Alexandra Wojna, Anna Stöger, Johannes Möst, Eva Leitner, Patrick Hyden, Thomas Rattei, Adele Habington, Ursula Wiedermann, Franz Allerberger, Werner Ruppitsch   +14 more
doaj   +1 more source

Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics

mSphere, 2016
During 2010 and 2012, California and Vermont, respectively, experienced statewide epidemics of pertussis with differences seen in the demographic affected, case clinical presentation, and molecular epidemiology of the circulating strains.
Katherine E. Bowden, Michael R. Weigand, Yanhui Peng, Pamela K. Cassiday, Scott Sammons, Kristen Knipe, Lori A. Rowe, Vladimir Loparev, Mili Sheth, Keeley Weening, M. Lucia Tondella, Margaret M. Williams   +11 more
doaj   +1 more source

Appearance of Bordetella pertussis Strains Not Expressing the Vaccine Antigen Pertactin in Finland [PDF]

Clinical and Vaccine Immunology, 2012
Despite extensive vaccinations, resurgence of pertussis has been reported in many countries ([9][1]). Recently, emergence of Bordetella pertussis isolates not expressing the vaccine antigen pertactin (Prn) or pertussis toxin was described in France, where surveillance of the clinical isolates ...
Barkoff, A-M, Mertsola, J, Guillot, S, Guiso, N, Berbers, G, He, Q   +5 more
openaire   +5 more sources

Development of High-Throughput Serum Bactericidal Assays for Bordetella pertussis to Evaluate BPZE1

Vaccines
Background/Objectives: Pertussis, caused by Bordetella pertussis, remains a global health problem, despite high vaccine coverage. In countries with high acellular pertussis vaccine (aPV) coverage, pertactin-negative B.
Peter Goldstein, Tania Gensale, Shannon Harris, Tina M. Green, Stephanie Noviello, Keith Rubin, Camille Locht, Breeze Cavell, Andrew Gorringe, Luc Gagnon   +9 more
doaj   +1 more source

Changes in Predominance of Pulsed-Field Gel Electrophoresis Profiles of Bordetella pertussis Isolates, United States, 2000–2012

Emerging Infectious Diseases, 2016
To clarify the characteristics of circulating Bordetella pertussis isolates, we used pulsed-field gel electrophoresis (PFGE) to analyze 5,262 isolates collected in the United States during 2000–2012.
Pamela K. Cassiday, Tami H. Skoff, Selina Jawahir, M. Lucia Tondella   +3 more
doaj   +1 more source

Fha Deficient Bordetella pertussis Isolates in Iran with 50 Years Whole Cell Pertussis Vaccination

Iranian Journal of Public Health, 2021
Background: Bordetella pertussis, a highly contagious respiratory. Notably, the resurgence of pertussis has recently been associated with the lacking production of vaccine virulence factors.
Samaneh Saedi, Azadeh Safarchi, Faranak Tayebzadeh Moghadam, Siamak Heidarzadeh, Vajihe Sadat Nikbin, Fereshteh Shahcheraghi   +5 more
doaj   +1 more source

Acellular Pertussis Vaccine Components: Today and Tomorrow

Vaccines, 2020
Pertussis is a highly communicable acute respiratory infection caused by Bordetella pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks occur cyclically worldwide and effective vaccination strategies are needed
Kalyan K. Dewan, Bodo Linz, Susan E. DeRocco, Eric T. Harvill   +3 more
doaj   +1 more source

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges

Journal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling, Frédéric Auvray, Mathieu Epardaud, Éric Oswald, Priscilla Branchu   +4 more
wiley   +1 more source